Reactome | RAB3A [cytosol]

RAB3A [cytosol]

Stable Identifier

R-CFA-8870429

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

GGC-RAB3A, A0A5F4D1A7

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - RAB geranylgeranylation (Canis familiaris)
    - RGGT geranylgeranylates RAB proteins (Canis familiaris)
      - CHMs:GGC-RABs:GDP [cytosol] (Canis familiaris)
        
        GGC-RABs:GDP [cytosol] (Canis familiaris)
        
        GGC-RABs [cytosol] (Canis familiaris)
        
        RAB3A [cytosol] (Canis familiaris)

Vesicle-mediated transport (Canis familiaris)

- Membrane Trafficking (Canis familiaris)
  - Rab regulation of trafficking (Canis familiaris)
    - RAB GEFs exchange GTP for GDP on RABs (Canis familiaris)
      - RAB3 GEFs exchange GTP for GDP on RAB3A (Canis familiaris)
        
        GGC-RAB3A:GDP:GDIs,CHMs [cytosol] (Canis familiaris)
        
        GGC-RAB3A:GDP [cytosol] (Canis familiaris)
        
        RAB3A [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A5F4D1A7

Gene Names

RAB3A

Reference Genes

BioGPS Gene:484826 RAB3A

ENSEMBL:ENSCAFG00000014945

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000014945 RAB3A

KEGG Gene (Canis lupus familiaris):484826 RAB3A

Monarch:484826 RAB3A

NCBI Gene:484826 RAB3A

Reference Transcript

RefSeq:XM_541942.5 RAB3A

Other Identifiers

484826

CfaAffx.22999.1.S1_s_at

GO:0000003

GO:0000166

GO:0000902

GO:0001669

GO:0001778

GO:0003016

GO:0003674

GO:0003924

GO:0005525

GO:0005575

GO:0005622

GO:0005737

GO:0005768

GO:0005886

GO:0006810

GO:0006886

GO:0006887

GO:0006950

GO:0007005

GO:0007009

GO:0007267

GO:0007274

GO:0007409

GO:0008021

GO:0008092

GO:0008150

GO:0009791

GO:0015031

GO:0016020

GO:0016079

GO:0016188

GO:0016192

GO:0017156

GO:0017157

GO:0021700

GO:0030154

GO:0030324

GO:0030742

GO:0031410

GO:0031489

GO:0031630

GO:0032418

GO:0034330

GO:0043167

GO:0043195

GO:0043226

GO:0045055

GO:0048172

GO:0048471

GO:0048489

GO:0048786

GO:0048790

GO:0048856

GO:0050877

GO:0050975

GO:0051602

GO:0060478

GO:0061024

GO:0061670

GO:0097091

GO:0098993

GO:1903307

GO:1905684

Participates

as a component of

GGC-RAB3A:GDP [cytosol] (Canis familiaris)

as a member of

GGC-RABs [cytosol] (Canis familiaris)

Other forms of this molecule

RAB3A [secretory granule membrane]

RAB3A [cytosol]

RAB3A [secretory granule membrane]

RAB3A [clathrin-sculpted acetylcholine transport vesicle membrane]

RAB3A [clathrin-sculpted glutamate transport vesicle membrane]

RAB3A [clathrin-sculpted monoamine transport vesicle membrane]

RAB3A [plasma membrane]

RAB3A [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]

Inferred From

GGC-RAB3A [cytosol] (Homo sapiens)

Modified Residues

Name

S-geranylgeranyl-L-cysteine at 218 (in Homo sapiens)

Coordinate

218

PsiMod Name

S-geranylgeranyl-L-cysteine [MOD:00113]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.

Name

S-geranylgeranyl-L-cysteine at 220 (in Homo sapiens)

Coordinate

220

PsiMod Name

S-geranylgeranyl-L-cysteine [MOD:00113]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.

Cross References

RefSeq

XP_541942.2

OpenTargets

ENSG00000105649

Ensembl

ENSCAFT00000075086, ENSCAFP00000059521, ENSCAFG00000014945

VGNC

45282