Reactome | RAB5B [cytosol]

RAB5B [cytosol]

Stable Identifier

R-CFA-8870434

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

GGC-RAB5B, E2QW69

Locations in the PathwayBrowser

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Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - RAB geranylgeranylation (Canis familiaris)
    - RGGT geranylgeranylates RAB proteins (Canis familiaris)
      - CHMs:GGC-RABs:GDP [cytosol] (Canis familiaris)
        
        GGC-RABs:GDP [cytosol] (Canis familiaris)
        
        GGC-RABs [cytosol] (Canis familiaris)
        
        RAB5B [cytosol] (Canis familiaris)

Vesicle-mediated transport (Canis familiaris)

- Membrane Trafficking (Canis familiaris)
  - Rab regulation of trafficking (Canis familiaris)
    - RAB GEFs exchange GTP for GDP on RABs (Canis familiaris)
      - RAB5 GEFs exchange GTP for GDP on RAB5 (Canis familiaris)
        
        GGC-RAB5:GDP:GDIs,CHMs [cytosol] (Canis familiaris)
        
        GGC-RAB5:GDP [cytosol] (Canis familiaris)
        
        GGC-RAB5 [cytosol] (Canis familiaris)
        
        RAB5B [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:E2QW69

Gene Names

RAB5B

Reference Genes

BioGPS Gene:474394 RAB5B

ENSEMBL:ENSCAFG00000000087

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000000087 RAB5B

KEGG Gene (Canis lupus familiaris):474394 RAB5B

Monarch:474394 RAB5B

NCBI Gene:474394 RAB5B

Reference Transcript

RefSeq:XM_531627.5 RAB5B

Other Identifiers

474394

Cfa.18078.1.S1_at

CfaAffx.1102.1.S1_at

GO:0003674

GO:0003924

GO:0005525

GO:0005575

GO:0005622

GO:0005737

GO:0005768

GO:0005769

GO:0005886

GO:0006810

GO:0006886

GO:0006897

GO:0007032

GO:0008150

GO:0012505

GO:0015031

GO:0016192

GO:0030100

GO:0030139

GO:0031410

GO:0043167

GO:0043226

GO:0070382

Participates

as a candidate of

Other forms of this molecule

RAB5B [clathrin-coated endocytic vesicle membrane]

RAB5B [early endosome membrane]

RAB5B [cytosol]

RAB5B [plasma membrane]

RAB5B [secretory granule membrane]

Inferred From

GGC-RAB5B [cytosol] (Homo sapiens)

Modified Residues

Name

S-geranylgeranyl-L-cysteine at 212 (in Homo sapiens)

Coordinate

212

PsiMod Name

S-geranylgeranyl-L-cysteine [MOD:00113]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.

Name

S-geranylgeranyl-L-cysteine at 213 (in Homo sapiens)

Coordinate

213

PsiMod Name

S-geranylgeranyl-L-cysteine [MOD:00113]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.

Cross References

RefSeq

XP_531627.2

OpenTargets

ENSG00000111540

Ensembl

ENSCAFG00000000087, ENSCAFP00000000123, ENSCAFT00000000142

VGNC

45292

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