Reactome | RAB27B [cytosol]

RAB27B [cytosol]

Stable Identifier

R-CFA-8873786

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

GGC-RAB27B, E2R5L5

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - RAB geranylgeranylation (Canis familiaris)
    - RGGT geranylgeranylates RAB proteins (Canis familiaris)
      - CHMs:GGC-RABs:GDP [cytosol] (Canis familiaris)
        
        GGC-RABs:GDP [cytosol] (Canis familiaris)
        
        GGC-RABs [cytosol] (Canis familiaris)
        
        RAB27B [cytosol] (Canis familiaris)

Vesicle-mediated transport (Canis familiaris)

- Membrane Trafficking (Canis familiaris)
  - Rab regulation of trafficking (Canis familiaris)
    - RAB GEFs exchange GTP for GDP on RABs (Canis familiaris)
      - MADD exchanges GTP for GDP on RAB27 (Canis familiaris)
        
        GGC-RAB27:GDP:GDIs,CHMs [cytosol] (Canis familiaris)
        
        RAB27:GDP [cytosol] (Canis familiaris)
        
        GGC-RAB27B:GDP [cytosol] (Canis familiaris)
        
        RAB27B [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:E2R5L5

Gene Names

RAB27B

Reference Genes

ENSEMBL:ENSCAFG00000000145

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000000145 RAB27B

Other Identifiers

483974

CfaAffx.1192.1.S1_at

GO:0003674

GO:0003924

GO:0003925

GO:0005525

GO:0005575

GO:0005622

GO:0005737

GO:0005768

GO:0005770

GO:0005794

GO:0005795

GO:0006810

GO:0008092

GO:0008150

GO:0016020

GO:0016192

GO:0019003

GO:0019904

GO:0030140

GO:0030141

GO:0031410

GO:0031489

GO:0032402

GO:0032585

GO:0042470

GO:0043167

GO:0043226

GO:0043473

GO:0045921

GO:0071985

Participates

as a component of

GGC-RAB27B:GDP [cytosol] (Canis familiaris)

as a candidate of

GGC-RABs [cytosol] (Canis familiaris)

Other forms of this molecule

RAB27B [melanosome membrane]

RAB27B [cytosol]

RAB27B [plasma membrane]

RAB27B [platelet dense granule membrane]

Inferred From

GGC-RAB27B [cytosol] (Homo sapiens)

Modified Residues

Name

S-geranylgeranyl-L-cysteine at 216 (in Homo sapiens)

Coordinate

216

PsiMod Name

S-geranylgeranyl-L-cysteine [MOD:00113]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.

Name

S-geranylgeranyl-L-cysteine at 218 (in Homo sapiens)

Coordinate

218

PsiMod Name

S-geranylgeranyl-L-cysteine [MOD:00113]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.

Cross References

OpenTargets

ENSG00000041353

Ensembl

ENSCAFT00000000237, ENSCAFG00000000145, ENSCAFP00000000213

VGNC

45268

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