IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5

Stable Identifier
R-CFA-8986985
Type
Reaction [omitted]
Species
Canis familiaris
Compartment
Synonyms
STAT1 is phosphorylated by IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 activated receptor complex, STAT1 is phosphorylated after IL29-IL29 receptor interaction
Locations in the PathwayBrowser
General
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This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Participants
Participates
Catalyst Activity

transmembrane receptor protein tyrosine kinase activity of IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1,STAT2, STAT3, STAT4, STAT5 [plasma membrane]

Inferred From
Created
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