Reactome | RAPGEF1 [cytosol]

RAPGEF1 [cytosol]

Stable Identifier

R-CFA-913472

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

RAPGEF1, A0A8I3P5F5

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:A0A8I3P5F5

Gene Names

RAPGEF1

Reference Genes

ENSEMBL:ENSCAFG00845018101.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845018101.1 RAPGEF1

Other Identifiers

491286

CfaAffx.30457.1.S1_s_at

GO:0001568

GO:0005085

GO:0007155

GO:0007264

GO:0007265

GO:0023052

GO:0043226

GO:0043231

GO:0043491

GO:0046580

GO:0048008

GO:0048856

GO:0051898

GO:0060070

GO:0061351

GO:0070371

GO:0070373

GO:0090090

GO:0098609

GO:0098772

GO:2000178

Participates

as a component of

p-CRKL:RAPGEF1 [cytosol] (Canis familiaris)
p(Y700,731,774)-CBL:CRK:RAPGEF1 [cytosol] (Canis familiaris)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] (Canis familiaris)
PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] (Canis familiaris)
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane] (Canis familiaris)

as a candidate of

RAC3 effectors [cytosol] (Canis familiaris)

as an input of

CBL:CRKL binds RAPGEF1 (Canis familiaris)
RAPGEF1 binds CRK,CRKL (Canis familiaris)
p130Cas and C3G bind PDGFR bound Crk (Canis familiaris)
p-FRS2:CRKL binds C3G (Canis familiaris)

Inferred From

RAPGEF1 [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000107263

Ensembl

ENSCAFP00845025208, ENSCAFG00845018101, ENSCAFT00845032249