Reactome | KCNJ15 [plasma membrane]

KCNJ15 [plasma membrane]

Stable Identifier

R-CFA-975292

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

KCNJ15, A0A8I3S6Y7

Locations in the PathwayBrowser

Expand all

Neuronal System (Canis familiaris)

- Potassium Channels (Canis familiaris)
  - Inwardly rectifying K+ channels (Canis familiaris)
    - G protein gated Potassium channels (Canis familiaris)
      - Activation of G protein gated Potassium channels (Canis familiaris)
        
        Activation of GIRK/Kir3 Channels (Canis familiaris)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Canis familiaris)
        
        Kir heterotetramers [plasma membrane] (Canis familiaris)
        
        Kir4.2:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)
        
        KCNJ15 [plasma membrane] (Canis familiaris)
        
        Kir heterotetramers [plasma membrane] (Canis familiaris)
        
        Kir4.2:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)
        
        KCNJ15 [plasma membrane] (Canis familiaris)
        
        Binding of Gbeta/gamma to GIRK/Kir3 channels (Canis familiaris)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Canis familiaris)
        
        Kir heterotetramers [plasma membrane] (Canis familiaris)
        
        Kir4.2:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)
        
        KCNJ15 [plasma membrane] (Canis familiaris)
        
        Kir heterotetramers [plasma membrane] (Canis familiaris)
        
        Kir4.2:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)
        
        KCNJ15 [plasma membrane] (Canis familiaris)
- Transmission across Chemical Synapses (Canis familiaris)
  - Neurotransmitter receptors and postsynaptic signal transmission (Canis familiaris)
    - GABA receptor activation (Canis familiaris)
      - GABA B receptor activation (Canis familiaris)
        
        Activation of GABAB receptors (Canis familiaris)
        
        Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits (Canis familiaris)
        
        Activation of GIRK/Kir3 Channels (Canis familiaris)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Canis familiaris)
        
        Kir heterotetramers [plasma membrane] (Canis familiaris)
        
        Kir4.2:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)
        
        KCNJ15 [plasma membrane] (Canis familiaris)
        
        Kir heterotetramers [plasma membrane] (Canis familiaris)
        
        Kir4.2:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)
        
        KCNJ15 [plasma membrane] (Canis familiaris)
        
        Binding of Gbeta/gamma to GIRK/Kir3 channels (Canis familiaris)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Canis familiaris)
        
        Kir heterotetramers [plasma membrane] (Canis familiaris)
        
        Kir4.2:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)
        
        KCNJ15 [plasma membrane] (Canis familiaris)
        
        Kir heterotetramers [plasma membrane] (Canis familiaris)
        
        Kir4.2:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)
        
        KCNJ15 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3S6Y7

Gene Names

KCNJ15

Reference Genes

BioGPS Gene:487759 KCNJ15

ENSEMBL:ENSCAFG00845028983.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845028983.1 KCNJ15

KEGG Gene (Canis lupus familiaris):487759 KCNJ15

Monarch:487759 KCNJ15

NCBI Gene:487759 KCNJ15

Reference Transcript

Other Identifiers

487759

CfaAffx.15401.1.S1_at

GO:0005215

GO:0005242

GO:0006813

GO:0016020

Participates

as a component of

Kir4.2:Kir5.1 heterotetramer [plasma membrane] (Canis familiaris)

Inferred From

KCNJ15 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_013965296.1, XP_013965306.1, XP_013965302.1, XP_013965303.1, XP_544884.2, XP_013965307.1, XP_013965300.1, XP_013965304.1, XP_013965298.1, XP_013965297.1, XP_013965301.1, XP_005638967.1, XP_013965305.1

OpenTargets

ENSG00000157551

Ensembl

ENSCAFT00845051250, ENSCAFP00845040195, ENSCAFG00845028983