O-glycosyl 3a [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier
R-COV-9694386
Type
Protein [EntityWithAccessionedSequence]
Species
Severe acute respiratory syndrome coronavirus 2
Compartment
Synonyms
P0DTC3
Locations in the PathwayBrowser for interactor UniProt:Q9H270 VPS11
General

SARS-CoV-2 mRNA2 open reading frame has a length of 3,822 nt and encodes the 1,273 aa spike preprotein (Wu et al, 2020).

Literature References
PubMed ID Title Journal Year
16474139 Glycosylation of the severe acute respiratory syndrome coronavirus triple-spanning membrane proteins 3a and M

Oostra, M, de Haan, CA, de Groot, RJ, Rottier, PJ

J. Virol. 2006
External Reference Information
External Reference
Gene Names
3a
Chain
chain:1-275
Reference Transcript
Participates
Other forms of this molecule
Inferred From
Modified Residues
Name
O-glycosyl-L-threonine at unknown position
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O3-glycosylthreonine.
Disease
Name Identifier Synonyms
COVID-19 DOID:0080600 2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection
Cross References
GlyGen
PDB
Interactors (17)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q96JC1 VPS39      0.916 13
 UniProt:Q96S66 CLCC1      0.725 4
 UniProt:Q8IWR1 TRI59      0.643 3
 UniProt:Q9H270 VPS11      0.643 3
 UniProt:P09601 HMOX1  4 0.643 3
 UniProt:Q8N6S5 AR6P6      0.643 3
 UniProt:Q9Y673 ALG5  1 0.643 3
 UniProt:P49754 VPS41      0.623 3
 UniProt:P61106 RAB14  7 0.527 2
 UniProt:Q9UH99 SUN2  1 0.527 2
 UniProt:O75976 CPD  3 0.527 2
 UniProt:P30519 HMOX2  3 0.527 2
 UniProt:Q9Y4P3 TBL2      0.527 2
 UniProt:P51153 RAB13  4 0.527 2
 UniProt:Q8NBJ7 SUMF2  1 0.527 2
 UniProt:Q9UNN8 PROCR  2 0.527 2
 UniProt:P0DTD1-PRO_0000449632 REP      0.488 2
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