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3a [endoplasmic reticulum lumen]
Stable Identifier
R-COV-9694584
Type
Protein [EntityWithAccessionedSequence]
Species
Severe acute respiratory syndrome coronavirus 2
Compartment
endoplasmic reticulum lumen
Synonyms
P0DTC3
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
Late SARS-CoV-2 Infection Events (Homo sapiens)
Translation of Structural Proteins (Homo sapiens)
Maturation of protein 3a (Homo sapiens)
3a translocates to the ERGIC (Homo sapiens)
3a [endoplasmic reticulum lumen] (Severe acute respiratory syndrome coronavirus 2)
mRNA3 is translated to protein 3a (Homo sapiens)
3a [endoplasmic reticulum lumen] (Severe acute respiratory syndrome coronavirus 2)
External Reference Information
External Reference
UniProt:P0DTC3 3a
Gene Names
3a
Chain
chain:1-275
Participates
as an output of
mRNA3 is translated to protein 3a (Homo sapiens)
as an input of
3a translocates to the ERGIC (Homo sapiens)
Other forms of this molecule
O-glycosyl 3a [virion membrane]
O-glycosyl 3a [endocytic vesicle membrane]
O-glycosyl 3a [endoplasmic reticulum-Golgi intermediate compartment membrane]
GalNAc-O-3a [endoplasmic reticulum-Golgi intermediate compartment]
3a [endoplasmic reticulum-Golgi intermediate compartment]
O-glycosyl 3a [endolysosome membrane]
O-glycosyl 3a [plasma membrane]
O-glycosyl 3a [extracellular region]
Disease
Name
Identifier
Synonyms
COVID-19
DOID:0080600
2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection
Cross References
PDB
8EQJ
,
7KJR
,
8EQT
,
8T5P
,
8EQU
,
6XDC
,
8T5Q
Interactors (44)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96JC1 VPS39
1
VPS39 [endosome membrane]
(R-HSA-2197806)
0.956
19
UniProt:Q96S66 CLCC1
0.875
9
UniProt:Q9H270 VPS11
1
VPS11 [endosome membrane]
(R-HSA-2197802)
0.823
7
UniProt:Q9Y673 ALG5
1
ALG5 [endoplasmic reticulum membrane]
(R-HSA-532211)
0.738
4
UniProt:P09601 HMOX1
4
HMOX1 [nucleoplasm]
(R-HSA-9708567)
HMOX1 [mitochondrial outer membrane]
(R-HSA-9708524)
HMOX1 [endoplasmic reticulum membrane]
(R-HSA-189395)
HMOX1 [cytosol]
(R-HSA-9609901)
0.738
4
UniProt:P0DTC3 3a
9
O-glycosyl 3a [virion membrane]
(R-COV-9694395)
O-glycosyl 3a [endocytic vesicle membrane]
(R-COV-9694729)
O-glycosyl 3a [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9694386)
GalNAc-O-3a [endoplasmic reticulum-Golgi intermediate compartment]
(R-COV-9694658)
3a [endoplasmic reticulum-Golgi intermediate compartment]
(R-COV-9694716)
3a [endoplasmic reticulum lumen]
(R-COV-9694584)
O-glycosyl 3a [endolysosome membrane]
(R-COV-9754541)
O-glycosyl 3a [plasma membrane]
(R-COV-9694433)
O-glycosyl 3a [extracellular region]
(R-COV-9694387)
0.716
4
UniProt:P49754 VPS41
1
VPS41 [endosome membrane]
(R-HSA-2197800)
0.695
4
UniProt:Q9UH99 SUN2
1
SUN2 [nuclear envelope]
(R-HSA-912382)
0.659
3
UniProt:Q8NBJ7 SUMF2
1
SUMF2 [endoplasmic reticulum lumen]
(R-HSA-1614305)
0.659
3
UniProt:Q8N6S5 AR6P6
0.643
3
UniProt:Q8IWR1 TRI59
0.643
3
UniProt:Q01518 CAP1
3
CAP1 [cytosol]
(R-HSA-350758)
CAP1 [extracellular region]
(R-HSA-350746)
CAP1 [azurophil granule lumen]
(R-HSA-6798752)
0.613
3
UniProt:P51809 VAMP7
6
VAMP7 [late endosome membrane]
(R-HSA-2193120)
VAMP7 [lysosomal membrane]
(R-HSA-376342)
VAMP7 [plasma membrane]
(R-HSA-376361)
VAMP7 [Golgi membrane]
(R-HSA-266197)
VAMP7 [cytoplasmic vesicle membrane]
(R-HSA-376336)
VAMP7 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869135)
0.602
4
UniProt:Q9P2Y5 UVRAG
2
UVRAG [cytosol]
(R-HSA-5668884)
UVRAG [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-9730510)
0.602
6
UniProt:Q12846 STX4
4
STX4 [phagocytic vesicle membrane]
(R-HSA-2029044)
STX4 [plasma membrane]
(R-HSA-181519)
STX4 [cytosol]
(R-HSA-114505)
p-STX4 [cytosol]
(R-HSA-114681)
0.602
4
UniProt:Q8NBS9 TXNDC5
4
TXNDC5 [Golgi lumen]
(R-HSA-434325)
TXNDC5 [lysosomal lumen]
(R-HSA-429813)
TXNDC5 [extracellular region]
(R-HSA-6806246)
TXNDC5 [azurophil granule lumen]
(R-HSA-6799367)
0.547
2
UniProt:Q96HE7 ERO1A
1
ERO1L [endoplasmic reticulum lumen]
(R-HSA-265076)
0.547
2
UniProt:P07205 PGK2
1
PGK2 [cytosol]
(R-HSA-6807622)
0.547
2
UniProt:P50454 SERPINH1
1
SERPINH1 [endoplasmic reticulum lumen]
(R-HSA-2127480)
0.547
2
UniProt:P35609 ACTN2
3
ACTN2 [cytosol]
(R-HSA-390562)
ACTN2 [platelet alpha granule lumen]
(R-HSA-349727)
ACTN2 [extracellular region]
(R-HSA-349725)
0.547
2
UniProt:Q92545 TM131
0.547
2
UniProt:Q9H0V9 LMAN2L
3
LMAN2L [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5689834)
LMAN2L [ER to Golgi transport vesicle membrane]
(R-HSA-5689832)
LMAN2L [endoplasmic reticulum membrane]
(R-HSA-5689469)
0.547
2
UniProt:P16422 EPCAM
1
EPCAM [plasma membrane]
(R-HSA-375068)
0.527
2
UniProt:O75976 CPD
3
CPD [Golgi membrane]
(R-HSA-432675)
CPD [cytoplasmic vesicle membrane]
(R-HSA-432671)
CPD [plasma membrane]
(R-HSA-9715182)
0.527
2
UniProt:P04439 HLA-A
9
K48polyUb-HLA-A A-2 [endoplasmic reticulum membrane]
(R-HSA-8943073)
HLA-A A-3 [endoplasmic reticulum membrane]
(R-HSA-8943090)
HLA class I histocompatibility antigen, A-3 alpha chain precursor [phagocytic vesicle membrane]
(R-HSA-1236740)
HLA class I histocompatibility antigen, A-3 alpha chain precursor [recycling endosome membrane]
(R-HSA-8863889)
HLA class I histocompatibility antigen, A-3 alpha chain precursor [early endosome membrane]
(R-HSA-1236826)
HLA class I histocompatibility antigen, A-3 alpha chain precursor [plasma membrane]
(R-HSA-197642)
HLA class I histocompatibility antigen, A-3 alpha chain precursor [Golgi membrane]
(R-HSA-983376)
HLA class I histocompatibility antigen, A-3 alpha chain precursor [ER to Golgi transport vesicle membrane]
(R-HSA-983347)
HLA class I histocompatibility antigen, A-3 alpha chain precursor [lumenal side of endoplasmic reticulum membrane]
(R-HSA-983100)
0.527
2
UniProt:P30519 HMOX2
3
HMOX2 [plasma membrane]
(R-HSA-6799676)
HMOX2 [specific granule membrane]
(R-HSA-6799628)
HMOX2 [endoplasmic reticulum membrane]
(R-HSA-189391)
0.527
2
UniProt:Q9UNN8 PROCR
2
PROCR(18-?) [extracellular region]
(R-HSA-5610109)
PROCR [plasma membrane]
(R-HSA-5591027)
0.527
2
UniProt:P61106 RAB14
7
GGC-RAB14 [cytoplasmic vesicle membrane]
(R-HSA-1445086)
GGC-RAB14 [recycling endosome membrane]
(R-HSA-8876593)
GGC-RAB14 [cytosol]
(R-HSA-8873763)
RAB14 [cytosol]
(R-HSA-8873701)
RAB14 [early endosome membrane]
(R-HSA-8871372)
RAB14 [plasma membrane]
(R-HSA-6806438)
RAB14 [tertiary granule membrane]
(R-HSA-6800407)
0.527
2
UniProt:Q9Y617 PSAT1
1
PXLP-K200-PSAT1 [cytosol]
(R-HSA-977330)
0.527
2
UniProt:Q9NRX4 PHP14
0.527
2
UniProt:P51153 RAB13
4
GGC-RAB13 [cytoplasmic vesicle membrane]
(R-HSA-1445110)
GGC-RAB13 [cell junction]
(R-HSA-8876591)
GGC-RAB13 [cytosol]
(R-HSA-8873767)
RAB13 [cytosol]
(R-HSA-8873674)
0.527
2
UniProt:Q15005 SPCS2
1
SPCS2 [endoplasmic reticulum membrane]
(R-HSA-264996)
0.527
2
UniProt:Q9Y4P3 TBL2
0.527
2
UniProt:P0DTD8 NS7B
0.519
3
UniProt:Q8NAF0 ZN579
0.499
2
UniProt:P0DTD1-PRO_0000449632 REP
0.488
2
UniProt:Q9P253 VPS18
1
VPS18 [endosome membrane]
(R-HSA-2197799)
0.483
2
UniProt:Q8NHV4 NEDD1
1
NEDD1 [cytosol]
(R-HSA-379267)
0.483
2
UniProt:Q9H269 VPS16
1
VPS16 [endosome membrane]
(R-HSA-2197803)
0.483
2
UniProt:Q12913 PTPRJ
2
PTPRJ [plasma membrane]
(R-HSA-6785269)
PTPRJ [specific granule membrane]
(R-HSA-6799570)
0.483
2
UniProt:P42765 ACAA2
1
ACAA2 [mitochondrial matrix]
(R-HSA-8874752)
0.482
2
UniProt:Q9H3K2 GHITM
0.482
2
UniProt:Q96GS4 BORC6
0.463
2
UniProt:Q9GZU1 MCOLN1
2
MCOLN1 [plasma membrane]
(R-HSA-3211764)
MCOLN1 [endosome membrane]
(R-HSA-917803)
0.463
2
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