Reactome | 9b [cytosol]

9b [cytosol]

Stable Identifier

R-COV-9694649

Type

Protein [EntityWithAccessionedSequence]

Species

Severe acute respiratory syndrome coronavirus 2

Compartment

cytosol

Synonyms

P0DTD2

Locations in the PathwayBrowser for interactor UniProt:Q9P0L2 MARK1

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External Reference Information

External Reference

UniProt:P0DTD2 9b

Gene Names

Chain

chain:1-97

Participates

as an input of

as an output of

mRNA9 is translated to protein 9b (Homo sapiens)

as a component of

9b homodimer [cytosol] (Severe acute respiratory syndrome coronavirus 2)

Other forms of this molecule

p-S53-9b [cytosol]

9b [mitochondrial outer membrane]

Inferred From

9b [cytosol] (Human SARS coronavirus)

Disease

Name	Identifier	Synonyms
COVID-19	DOID:0080600	2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection

Cross References

PDB

7DHG, 7KDT, 6Z4U, 7YE7, 7YE8

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O94826 TOMM70	2	PolyUb-TOMM70A [mitochondrial outer membrane] (R-HSA-6783033) TOMM70 [mitochondrial outer membrane] (R-HSA-1252129)	0.976	28
UniProt:P0DTD2 9b	3	p-S53-9b [cytosol] (R-COV-9758478) 9b [cytosol] (R-COV-9694649) 9b [mitochondrial outer membrane] (R-COV-9709803)	0.779	5
UniProt:Q9UKA9 PTBP2			0.527	2
UniProt:Q9H773 DCTPP1	1	DCTPP1 [cytosol] (R-HSA-6786263)	0.527	2
UniProt:Q9P0L2 MARK1			0.527	2
UniProt:Q9H2P9 DPH5	1	DPH5 [cytosol] (R-HSA-5358485)	0.527	2
UniProt:O75534 CSDE1			0.527	2
UniProt:P0DMV8 HSPA1A	4	HSPA1A [nucleoplasm] (R-HSA-6792605) HSPA1A [cytosol] (R-HSA-6792602) HSPA1A [extracellular region] (R-HSA-6805872) HSPA1A [ficolin-1-rich granule lumen] (R-HSA-6801496)	0.527	2
UniProt:P27448 MARK3	1	MARK3 [cytosol] (R-HSA-5672591)	0.527	2
UniProt:O14745 NHRF1			0.527	2
UniProt:Q7KZI7 MARK2			0.527	2
UniProt:Q9UL15 BAG5	1	BAG5 [cytosol] (R-HSA-5255453)	0.527	2
UniProt:O43633 CHMP2A	2	CHMP2A [cytosol] (R-HSA-917734) CHMP2A [endosome membrane] (R-HSA-9631172)	0.527	2
UniProt:P0DTD1-PRO_0000449625 REP			0.488	2
UniProt:Q7Z434 MAVS	2	MAVS [mitochondrial outer membrane] (R-HSA-913730) K48polyUb-MAVS [mitochondrial outer membrane] (R-HSA-983463)	0.463	2
UniProt:Q9Y6K9 IKBKG	12	IKBKG D406V [cytosol] (R-HSA-5262943) IKBKG L153R [cytosol] (R-HSA-5262879) IKBKG E391* [cytosol] (R-HSA-5262924) IKBKG C417R [cytosol] (R-HSA-5262858) IKBKG R173G [cytosol] (R-HSA-5262966) IKBKG R175P [cytosol] (R-HSA-5262916) IKBKG 420Wext447 [cytosol] (R-HSA-5262978) monoSUMO1-K277,K309-IKBKG [nucleoplasm] (R-HSA-4755449) IKBKG [nucleoplasm] (R-HSA-4755413) K63polyUb-IKBKG [cytosol] (R-HSA-202530) Ub-285-IKBKG [cytosol] (R-HSA-741397) IKBKG [cytosol] (R-HSA-168108)	0.463	3
UniProt:Q9BYX4 IFIH1	3	IFIH1 [cytosol] (R-HSA-913536) K48polyUb-IFIH1 [cytosol] (R-HSA-3080557) PolyUb-IFIH1 [cytosol] (R-HSA-6782812)	0.463	2
UniProt:O95786 RIGI	4	PolyUb-DDX58 [cytosol] (R-HSA-6782770) K48polyUb-DDX58 [cytosol] (R-HSA-3080568) K63polyUb-DDX58 [cytosol] (R-HSA-918191) DDX58 [cytosol] (R-HSA-168917)	0.463	2
UniProt:Q86WV6 STING1	5	K63polyUb-STING [cytoplasmic vesicle membrane] (R-HSA-3248021) K63polyUb-STING [endoplasmic reticulum membrane] (R-HSA-3134805) TMEM173 [plasma membrane] (R-HSA-6804815) TMEM173 [secretory granule membrane] (R-HSA-6804798) STING [endoplasmic reticulum membrane] (R-HSA-1834940)	0.463	2
UniProt:Q9UHD2 TBK1	5	pS-172,K48polyUb-TBK1 [cytosol] (R-HSA-3249397) p-TBK1 [cytosol] (R-HSA-9008705) K63polyUb-K30,K401-TBK1 [cytosol] (R-HSA-9730430) TBK1 [cytosol] (R-HSA-166267) p-S172-TBK1 [cytosol] (R-HSA-168379)	0.463	2

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