high-mannose N-glycan-PALM-Spike [endoplasmic reticulum lumen]

Stable Identifier
R-COV-9696917
Type
Protein [EntityWithAccessionedSequence]
Species
Severe acute respiratory syndrome coronavirus 2
Compartment
Locations in the PathwayBrowser for interactor UniProt:Q8IUN9 CLEC10A
Literature References
PubMed ID Title Journal Year
32366695 Site-specific glycan analysis of the SARS-CoV-2 spike

Watanabe, Y, Allen, JD, Wrapp, D, McLellan, JS, Crispin, M

Science 2020
External Reference Information
External Reference
Gene Names
S, 2
Chain
signal peptide:1-12, chain:13-1273, chain:13-685, chain:686-1273, chain:816-1273
Reference Transcript
Participates
Other forms of this molecule
Modified Residues
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 1074
Coordinate
1074
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 1098
Coordinate
1098
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 1134
Coordinate
1134
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 1158
Coordinate
1158
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 1173
Coordinate
1173
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 1194
Coordinate
1194
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 122
Coordinate
122
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 149
Coordinate
149
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 165
Coordinate
165
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 17
Coordinate
17
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 282
Coordinate
282
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 331
Coordinate
331
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 343
Coordinate
343
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 603
Coordinate
603
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 61
Coordinate
61
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 616
Coordinate
616
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 657
Coordinate
657
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 709
Coordinate
709
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 717
Coordinate
717
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 74
Coordinate
74
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at 801
Coordinate
801
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
N4-(N-acetylamino)glucosyl-L-asparagine (Man(9) N-glycan group) at 234
Coordinate
234
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Name
palmitoylated-L-cysteine at unknown position
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to a palmitoylated-L-cysteine, such as N-palmitoyl-L-cysteine or S-palmitoyl-L-cysteine.
Disease
Name Identifier Synonyms
COVID-19 DOID:0080600 2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection
Cross References
GlyGen
PDB
7A5R, 7KXK, 7CN9, 7DPM, 7L5B, 7JVC, 6YM0, 7C8J, 7DK7, 7BYR, 7C2L, 7CHC, 6ZOW, 6ZP1, 7LD1, 6ZDG, 7L02, 7KSG, 7CM4, 7K8Y, 7A95, 6X2C, 7CAK, 6LVN, 7KN6, 6ZLR, 7DMU, 7ND9, 6XC4, 7JMP, 7A98, 7C01, 7KEC, 7KLW, 7BEH, 7KGK, 6XS6, 7A5S, 7DK3, 7CDI, 7KKL, 6ZER, 7KDG, 7KJ2, 7DCC, 7BEL, 7KMB, 7BZ5, 7L7F, 6WPS, 6M0J, 7L06, 7JZN, 7KML, 7KDL, 6XEY, 6ZHD, 7DF3, 6ZDH, 7L7K, 7K43, 7ND5, 6YOR, 6LXT, 7JV2, 7CWN, 7CAN, 7NDA, 6XE1, 6XM0, 6X79, 7C8D, 6ZGI, 7KXJ, 6VXX, 7BEJ, 7CHB, 7DK6, 7KMI, 7K8T, 7CHH, 7KJ5, 6Z43, 7KS9, 7BEP, 6XKQ, 7LCN, 7ND3, 6YZ5, 6X2A, 7KLH, 7L2C, 7KN5, 7CAI, 7KE7, 7A97, 7ND8, 7CWL, 7BWJ, 7B17, 7KGJ, 7DDN, 7BEK, 7A29, 7KKK, 7D30, 7JVB, 7KNI, 6ZCZ, 7CJF, 7KDK, 6ZP0, 6ZH9, 6VYB, 7JJJ, 7JZM, 7KMK, 7L3N, 7A4N, 7K8X, 6X2B, 6YZ7, 7A94, 7NEH, 6XDG, 7KE8, 7ND4, 6XC3, 7CWM, 7DDD, 7JMO, 6X6P, 6YLA, 7CT5, 6XLU, 6ZGG, 7NDC, 7JWY, 7BEI, 6XM5, 7KNE, 6ZB5, 7DK5, 7K9Z, 7KMH, 7C8W, 6XKP, 7K8V, 6X29, 6ZP7, 6XF6, 7CAC, 7KE6, 7DD2, 6XR8, 7A92, 7KMZ, 6ZXN, 7A96, 7CH4, 7ND7, 7CWS, 6ZGE, 7JV6, 7NDD, 6VW1, 7KNH, 7JX3, 7A25, 7CWU, 7JJI, 7JVA, 7LOP, 6XCN, 7KJ4, 7KDJ, 7BEO, 6VSB, 7D2Z, 7CHF, 7K8S, 6ZOZ, 7K8W, 7JZL, 7DD8, 6ZBP, 7A93, 6Z2M, 7KLG, 7CAH, 6XRA, 6XC2, 6Z97, 7KEB, 7CH5, 7L0N, 6XM3, 7NDB, 6ZB4, 7CDJ, 7KDH, 6XCM, 6XKL, 7BEM, 6ZP2, 6ZWV, 6ZOX, 7C8V, 6XF5, 7CAB, 7K8U, 7JW0, 6M17, 7DCX, 7A91, 7DF4, 7K8Z, 6LZG, 7KE4, 7KE9, 6ZFO, 7KN7, 7K45, 6XC7, 7JMW, 7KZB, 6XM4, 7DK4, 6M1V, 7JJC, 7AD1, 7K4N, 7KJ3, 6W41, 7K8M, 7BEN, 7CHE, 7KMG, 6ZOY, 7KDI, 6ZP5, 6WPT, 7K90, 7KL9, 7KMS, 7L09, 7ND6, 7JWB, 7JZU, 7KEA, 7KNB, 7JV4, 7CWO
Interactors (30)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9BYF1 ACE2  5 0.996 161
 UniProt:P0DTC2 S  16 0.982 47
 UniProt:P09958 FURIN  4 0.854 5
 UniProt:Q9NNX6 CD209  1 0.766 6
 UniProt:Q9C0B5 ZDHC5      0.725 5
 UniProt:Q7Z5G4 GOLGA7  3 0.725 5
 UniProt:Q9H2X3 CLC4M      0.71 5
 UniProt:Q96D42 HAVR1      0.667 7
 UniProt:P30530 AXL  2 0.655 9
 UniProt:P35613 BSG  2 0.652 7
 IntAct:EBI-26657218 PEPTIDE      0.645 7
 UniProt:P11021 HSPA5  6 0.644 6
 UniProt:O14786 NRP1  1 0.639 9
 UniProt:Q8IUN9 CLEC10A  1 0.623 4
 ChEBI:28304 HEPARIN      0.623 5
 UniProt:Q96LC7 SIGLEC10  1 0.623 2
 UniProt:P07711 CTSL  8 0.623 3
 cholesterol [ChEBI:16113]  20 0.558 5
 lipopolysaccharide [ChEBI:16412]  5 0.558 3
 UniProt:Q8IUN9-2 CLEC10A      0.558 3
 UniProt:Q61830 Mrc1  4 0.558 2
 UniProt:P35247 SFTPD  4 0.544 3
 UniProt:P00533 EGFR  59 0.537 4
 UniProt:P01130 LDLR  4 0.537 4
 IntAct:EBI-26657222 PEPTIDE      0.525 2
 IntAct:EBI-26657225 PEPTIDE      0.525 2
 linoleic acid [ChEBI:17351]  6 0.522 2
 UniProt:P0DTD1-PRO_0000449625 REP      0.488 2
 UniProt:P0DTD1-PRO_0000449627 REP      0.488 2
 UniProt:P0DTD1-PRO_0000449628 REP      0.488 2
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