Ub-3xPalmC-E [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier
R-COV-9698420
Type
Protein [EntityWithAccessionedSequence]
Species
Severe acute respiratory syndrome coronavirus 2
Compartment
endoplasmic reticulum-Golgi intermediate compartment membrane
Synonyms
P0DTC4
Locations in the PathwayBrowser
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General
SARS-CoV-2 mRNA2 open reading frame has a length of 3,822 nt and encodes the 1,273 aa spike preprotein (Wu et al, 2020).
External Reference Information
External Reference
UniProt:P0DTC4 E
Gene Names
E, 4
Chain
chain:1-75
Participates
as a component of
Other forms of this molecule
N-glycan E [endoplasmic reticulum lumen]
nascent E [endoplasmic reticulum lumen]
3xPalmC-E [endoplasmic reticulum lumen]
Ub-3xPalmC-E [endoplasmic reticulum lumen]
Ub-3xPalmC-E [endoplasmic reticulum membrane]
Ub-3xPalmC-E [Golgi membrane]
Ub-3xPalmC-E [endocytic vesicle membrane]
Ub-3xPalmC-E [virion membrane]
Inferred From
Ub-3xPalmC-E [Golgi membrane] (Human SARS coronavirus)
Modified Residues
Name
palmitoylated-L-cysteine at 40
Coordinate
40
PsiMod Name
palmitoylated-L-cysteine
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to a palmitoylated-L-cysteine, such as N-palmitoyl-L-cysteine or S-palmitoyl-L-cysteine.
Name
palmitoylated-L-cysteine at 43
Coordinate
43
PsiMod Name
palmitoylated-L-cysteine
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to a palmitoylated-L-cysteine, such as N-palmitoyl-L-cysteine or S-palmitoyl-L-cysteine.
Name
palmitoylated-L-cysteine at 44
Coordinate
44
PsiMod Name
palmitoylated-L-cysteine
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to a palmitoylated-L-cysteine, such as N-palmitoyl-L-cysteine or S-palmitoyl-L-cysteine.
Name
ubiquitinylated lysine at 63
Coordinate
63
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Disease
Name Identifier Synonyms
COVID-19 DOID:0080600 2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection
Cross References
PDB
Interactors (21)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q8N3R9 MPP5  2 0.798 6
 UniProt:P0DTC4 E  9 0.767 6
 UniProt:P0DTC5 M  10 0.674 5
 UniProt:Q86VM9 ZCH18      0.659 3
 UniProt:P61165 TM258      0.556 3
 UniProt:O75360 PROP1      0.556 3
 UniProt:O95429 BAG4  3 0.556 3
 UniProt:P0DTC9 N  13 0.553 3
 UniProt:Q07021-PRO_0000018590 C1QBP      0.544 2
 UniProt:P05023 ATP1A1  1 0.527 2
 UniProt:O00203 AP3B1  4 0.527 2
 UniProt:Q8IWA5 SLC44A2  2 0.527 2
 UniProt:P16615 ATP2A2  2 0.527 2
 UniProt:P25440 BRD2  1 0.527 2
 UniProt:Q9P035 HACD3  1 0.527 2
 UniProt:O60885 BRD4  1 0.527 2
 UniProt:Q6UX04 CWC27  1 0.527 2
 UniProt:P0DTD8 NS7B      0.519 5
 UniProt:Q96BA8 CREB3L1  7 0.488 2
 UniProt:P12268 IMPDH2  4 0.482 2
 UniProt:P62805 H4C1  17 0.482 2
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