Reactome | p-8S-N [cytosol]

p-8S-N [cytosol]

Stable Identifier

R-COV-9729335

Type

Protein [EntityWithAccessionedSequence]

Species

Severe acute respiratory syndrome coronavirus 2

Compartment

cytosol

Synonyms

p-S176,180,184,188,194,202,206,T198-N

Locations in the PathwayBrowser for interactor UniProt:O43818 RRP9

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Literature References

PubMed ID	Title	Journal	Year
33997890	Variable posttranslational modifications of severe acute respiratory syndrome coronavirus 2 nucleocapsid protein Supekar, NT, Shajahan, A, Gleinich, AS, Rouhani, DS, Heiss, C, Chapla, DG, Moremen, KW, Azadi, P	Glycobiology	2021
19106108	Glycogen synthase kinase-3 regulates the phosphorylation of severe acute respiratory syndrome coronavirus nucleocapsid protein and viral replication Wu, CH, Yeh, SH, Tsay, YG, Shieh, YH, Kao, CL, Chen, YS, Wang, SH, Kuo, TJ, Chen, DS, Chen, PJ	J. Biol. Chem.	2009

External Reference Information

External Reference

UniProt:P0DTC9 N

Gene Names

Chain

chain:1-419

Reference Genes

BioGPS Gene:43740575 N

Monarch:43740575 N

NCBI Gene:43740575 N

UCSC:P0DTC9 N

Reference Transcript

RefSeq:NC_045512.2 E

Participates

as an output of

GSK3 phosphorylates nucleoprotein (Homo sapiens)

as an input of

CSNK1A1 phosphorylates nucleoprotein (Homo sapiens)

Other forms of this molecule

SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]

SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]

ADPr-p-11S,2T-metR95,177-N [cytosol]

p-11S,2T-metR95,177-N [cytosol]

p-11S,2T-N [cytosol]

p-8S,2T-N [cytosol]

p-S188,206-N [cytosol]

N [cytosol]

SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]

N [plasma membrane]

SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]

SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]

Modified Residues

Name

O-phospho-L-serine at 188

Coordinate

188

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at 206

Coordinate

206

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at 176

Coordinate

176

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at 180

Coordinate

180

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at 184

Coordinate

184

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at 194

Coordinate

194

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-threonine at 198

Coordinate

198

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Name

O-phospho-L-serine at 202

Coordinate

202

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Disease

Name	Identifier	Synonyms
COVID-19	DOID:0080600	2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection

Cross References

RefSeq

YP_009724397.2

Mondo

0100096

PDB

8IQJ, 7LGD, 8J6X, 7SD4, 8IV3, 7YLD, 7YLB, 8W6W, 9F2G, 7XX1, 7QIK, 7QIP, 7KGP, 7KGR, 7WZO, 7UXZ, 7VBE, 7CDZ, 7UW3, 7LTU, 7KGO, 7KGQ, 6YUN, 7VNU, 6M3M, 8TH1, 7CR5, 6ZCO, 7O35, 9EWH, 7XWX, 7F2B, 7ZIT, 7LUX, 7PKU, 7O36, 8TFD, 7LV2, 8DNT, 7XWZ, 7N0R, 8X1H, 6YI3, 9EZB, 9F83, 7STS, 7STR, 6VYO, 9F2H, 7CE0, 9EVY, 7WKJ, 7KGT, 9EXB, 7KGS, 6WJI, 7XXK, 7F2E, 7DE1, 8TH5, 7VBD, 7VBF, 6WKP, 7SUE, 7SUO, 7N0I, 7R98, 6WZQ, 7O05, 9F2I, 7UXX, 7LUZ, 7N3D, 9F5J, 9CJ6, 9F5L, 7N3C, 9F7C, 7ACT, 7ACS, 9F7A, 6WZO, 7C22, 9FBG

Interactors (199)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC9 N	13	SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729340) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9729341) ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729275) p-11S,2T-metR95,177-N [cytosol] (R-COV-9729308) p-11S,2T-N [cytosol] (R-COV-9729264) p-8S,2T-N [cytosol] (R-COV-9729277) p-8S-N [cytosol] (R-COV-9729335) p-S188,206-N [cytosol] (R-COV-9729324) N [cytosol] (R-COV-9694300) SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol] (R-COV-9756489) N [plasma membrane] (R-COV-9694356) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus] (R-COV-9729339) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane] (R-COV-9729325)	0.994	105
UniProt:Q13283 G3BP1	1	G3BP1 [cytosol] (R-HSA-9729517)	0.984	71
UniProt:Q9UN86 G3BP2	1	G3BP2 [cytosol] (R-HSA-9729507)	0.969	37
IntAct:EBI-26871880 GENOMIC			0.948	38
UniProt:Q9HCE1 MOV10	1	MOV10 [cytosol] (R-HSA-427772)	0.911	11
UniProt:Q9NR30 DDX21	1	DDX21 [nucleoplasm] (R-HSA-5250652)	0.874	12
UniProt:Q14258 TRIM25	2	TRIM25 [nucleoplasm] (R-HSA-5653667) TRIM25 [cytosol] (R-HSA-918186)	0.86	13
UniProt:P19525 EIF2AK2	5	EIF2AK2 [cytosol] (R-HSA-168699) p-EIF2AK2 [cytosol] (R-HSA-9833834) ISG15-EIF2AK2 [cytosol] (R-HSA-9833968) SUMO-EIF2AK2 [cytosol] (R-HSA-9834829) p-EIF2AK2 [nucleoplasm] (R-HSA-9836332)	0.822	8
UniProt:P11940 PABPC1	1	PABPC1 [cytosol] (R-HSA-156803)	0.798	5
UniProt:Q6PKG0 LARP1	1	LARP1 [cytosol] (R-HSA-9760421)	0.788	5
UniProt:O95786 RIGI	4	DDX58 [cytosol] (R-HSA-168917) K63polyUb-DDX58 [cytosol] (R-HSA-918191) K48polyUb-DDX58 [cytosol] (R-HSA-3080568) PolyUb-DDX58 [cytosol] (R-HSA-6782770)	0.786	15
UniProt:O75569 PRKRA	2	p-S246,S287-PRKRA [cytosol] (R-HSA-9834791) PRKRA [cytosol] (R-HSA-2399897)	0.778	8
UniProt:Q9HC36 MRM3	1	RNMTL1 [mitochondrial matrix] (R-HSA-6793067)	0.768	5
UniProt:Q9NX58 LYAR			0.765	6
UniProt:P52630 STAT2	4	p-Y690-STAT2 [cytosol] (R-HSA-909683) STAT2 [cytosol] (R-HSA-882029) p-Y690-STAT2 [nucleoplasm] (R-HSA-909673) p-Y-STAT2 [cytosol] (R-HSA-8987235)	0.76	7
UniProt:Q14444 CAPR1			0.744	5
UniProt:P0DTD1-PRO_0000449621 REP			0.741	15
UniProt:P38159 RBMX	2	RBMX [cytosol] (R-HSA-9715135) RBMX [nucleoplasm] (R-HSA-71939)	0.725	4
UniProt:Q13151 HNRNPA0	1	HNRNPA0 [nucleoplasm] (R-HSA-71925)	0.725	4
UniProt:Q1KMD3 HNRL2			0.725	4
UniProt:Q13310 PABP4			0.725	4
UniProt:P16403 H1-2	1	HIST1H1C [nucleoplasm] (R-HSA-211237)	0.725	4
UniProt:P22087 FBL	1	FBL [nucleoplasm] (R-HSA-6790638)	0.725	6
UniProt:O60506 HNRPQ			0.725	4
UniProt:O43390 HNRNPR	1	HNRNPR [nucleoplasm] (R-HSA-71951)	0.725	5
UniProt:Q8NCA5 FA98A			0.725	5
UniProt:Q6NZI2 CAVIN1	2	PTRF [nucleoplasm] (R-HSA-74981) CAVIN1 [plasma membrane] (R-HSA-9714278)	0.725	5
UniProt:Q9NW13 RBM28	1	RBM28 [nucleoplasm] (R-HSA-6791192)	0.725	4
UniProt:Q96SB4 SRPK1	2	SRPK1 [cytosol] (R-HSA-9729349) SRPK1 [nucleoplasm] (R-HSA-9821984)	0.713	3
UniProt:P62937 PPIA	5	PPIA [extracellular region] (R-HSA-173646) PPIA [secretory granule lumen] (R-HSA-6801400) PPIA [ficolin-1-rich granule lumen] (R-HSA-6801391) PPIA [cytosol] (R-HSA-173123) PPIA [extracellular exosome] (R-HSA-6801538)	0.713	3
UniProt:P10412 H1-4	1	HIST1H1E [nucleoplasm] (R-HSA-211251)	0.708	5
UniProt:P42224 STAT1	8	STAT1 [cytosol] (R-HSA-629622) p-Y701-STAT1 [nucleoplasm] (R-HSA-6788624) p-Y701-STAT1 [cytosol] (R-HSA-8951202) p-Y701-STAT1 [nucleoplasm] (R-HSA-8985905) p-STAT1 [cytosol] (R-HSA-8950418) p-STAT1 [nucleoplasm] (R-HSA-8987140) p-Y701-STAT1 [cytosol] (R-HSA-3132766) p-Y701,S727-STAT1 [cytosol] (R-HSA-9850842)	0.706	6
IntAct:EBI-26608251 NC			0.705	15
UniProt:P62899 RPL31	1	RPL31 [cytosol] (R-HSA-72454)	0.702	6
UniProt:P62753 RPS6	4	RPS6 [cytosol] (R-HSA-72381) p-5S-RPS6 [cytosol] (R-HSA-165727) 3OHR147-RPS6 [cytosol] (R-HSA-9629876) RPS6 [nucleoplasm] (R-HSA-6790606)	0.702	6
UniProt:Q15014 MORF4L2	1	MORF4L2 [nucleoplasm] (R-HSA-3322945)	0.697	5
UniProt:Q15633 TARBP2	2	p-TARBP2 [cytosol] (R-HSA-9835348) TARBP2 [cytosol] (R-HSA-203864)	0.697	5
UniProt:O15145 ARPC3	1	ARPC3 [cytosol] (R-HSA-200812)	0.696	5
UniProt:Q13895 BYSL	2	BYSL [nucleoplasm] (R-HSA-6791526) BYSL [cytosol] (R-HSA-6791518)	0.696	5
IntAct:EBI-26982027 T6			0.695	6
IntAct:EBI-26982037 T10			0.695	7
ChEBI:15422 ATP			0.689	6
ChEBI:84491 POLY(I			0.682	3
UniProt:P0DTC5 M	10	M [plasma membrane] (R-COV-9755780) N-glycan M [virion membrane] (R-COV-9694385) M [virion membrane] (R-COV-9694320) M [endocytic vesicle membrane] (R-COV-9694563) N-glycan M [endocytic vesicle membrane] (R-COV-9694738) M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694439) N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694446) M [endoplasmic reticulum membrane] (R-COV-9767620) nascent M [endoplasmic reticulum lumen] (R-COV-9694279) N-glycan M [endoplasmic reticulum membrane] (R-COV-9694684)	0.674	6
UniProt:Q96HA8 NTAQ1			0.666	4
UniProt:P57764 GSDMD	13	GSDMD(1-275) [cytosol] (R-HSA-9647641) GSDMD [cytosol] (R-HSA-6801577) GSDMD(1-87) [cytosol] (R-HSA-9686099) GSDMD(88-484) [cytosol] (R-HSA-9686133) dithiocarb-C191-GSDMD(1-275) [cytosol] (R-HSA-9693317) GSDMD(269-484) [cytosol] (R-HSA-9710116) GSDMD(1-268) [cytosol] (R-HSA-9710104) GSDMD(276-484) [cytosol] (R-HSA-9647672) S-(2-succinyl)-C191-GSDMD [cytosol] (R-HSA-9716198) GSDMD [tertiary granule lumen] (R-HSA-6801501) GSDMD [extracellular region] (R-HSA-6801576) GSDMD [specific granule lumen] (R-HSA-6801468) GSDMD [ficolin-1-rich granule lumen] (R-HSA-6801498)	0.659	13
UniProt:O76021 RL1D1			0.643	3
UniProt:Q92522 H1X			0.643	4
UniProt:P62701 RPS4X	2	RPS4X [cytosol] (R-HSA-72375) RPS4X [nucleoplasm] (R-HSA-6798713)	0.643	5
UniProt:Q07020 RPL18	1	RPL18 [cytosol] (R-HSA-72420)	0.643	3
UniProt:Q99729 ROAA			0.643	3
UniProt:Q08211 DHX9	3	DHX9 [cytosol] (R-HSA-847700) p-DHX9 [cytosol] (R-HSA-9836168) DHX9 [nucleoplasm] (R-HSA-53517)	0.643	4
UniProt:Q6P158 DHX57			0.643	3
UniProt:P22626 HNRNPA2B1	2	HNRNPA2B1 [nucleoplasm] (R-HSA-71929) HNRNPA2B1 [extracellular exosome] (R-HSA-8950304)	0.643	3
UniProt:Q8TAD8 SNIP1	1	SNIP1 [nucleoplasm] (R-HSA-3222315)	0.643	3
UniProt:Q9Y3C1 NOP16			0.643	4
UniProt:Q92900 UPF1	2	UPF1 [cytosol] (R-HSA-927734) p-4S-UPF1 [cytosol] (R-HSA-927856)	0.643	3
UniProt:P62750 RPL23A	1	RPL23A [cytosol] (R-HSA-72432)	0.643	4
UniProt:P51991 HNRNPA3	1	HNRNPA3 [nucleoplasm] (R-HSA-71931)	0.643	3
UniProt:P18621 RPL17	1	RPL17 [cytosol] (R-HSA-72418)	0.643	4
UniProt:P46776 RPL27A	3	RPL27A [cytosol] (R-HSA-72442) RPL27A [nucleoplasm] (R-HSA-9630984) 3OHH39-RPL27A [nucleoplasm] (R-HSA-9630970)	0.643	3
UniProt:Q8TDD1 DDX54			0.643	3
UniProt:Q9Y3U8 RPL36	1	RPL36 [cytosol] (R-HSA-72464)	0.643	3
UniProt:Q9NZB2 F120A			0.643	3
UniProt:P62241 RPS8	2	RPS8 [cytosol] (R-HSA-72385) RPS8 [nucleoplasm] (R-HSA-6791203)	0.643	4
UniProt:P09651 HNRNPA1	2	HNRNPA1 [nucleoplasm] (R-HSA-71927) HNRNPA1 [cytosol] (R-HSA-9727902)	0.643	4
UniProt:P67870 CSNK2B	5	CSNK2B [cytosol] (R-HSA-201693) CSNK2B [nucleoplasm] (R-HSA-6805067) CSNK2B [secretory granule lumen] (R-HSA-6801319) CSNK2B [extracellular region] (R-HSA-6806508) CSNK2B [ficolin-1-rich granule lumen] (R-HSA-6801290)	0.643	3
UniProt:P62847 RPS24	2	RPS24 [cytosol] (R-HSA-72355) RPS24 [nucleoplasm] (R-HSA-6791186)	0.643	4
UniProt:Q00839 HNRNPU	1	HNRNPU [nucleoplasm] (R-HSA-71953)	0.643	5
UniProt:P46087 NOP2	1	NOP2 [nucleoplasm] (R-HSA-6790922)	0.643	3
UniProt:P46781 RPS9	2	RPS9 [cytosol] (R-HSA-72387) RPS9 [nucleoplasm] (R-HSA-6790663)	0.643	4
UniProt:P62244 RPS15A	2	RPS15A [cytosol] (R-HSA-72345) RPS15A [nucleoplasm] (R-HSA-6791191)	0.643	3
Poly(U)			0.642	4
UniProt:Q96P20 NLRP3	2	NLRP3 [cytosol] (R-HSA-561189) K63polyUb-NLRP3 [cytosol] (R-HSA-6783288)	0.628	18
IntAct:EBI-26870604 5'-400			0.62	5
IntAct:EBI-26902561 30-BP RNA VIRAL OLIGO, ORF8 REGION			0.615	11
UniProt:Q92499 DDX1	1	DDX1 [nucleoplasm] (R-HSA-5696771)	0.602	3
UniProt:Q9UBU8 MORF4L1	1	MORF4L1 [nucleoplasm] (R-HSA-3321982)	0.601	4
UniProt:Q08426 EHHADH	2	EHHADH [peroxisomal matrix] (R-HSA-400155) EHHADH [cytosol] (R-HSA-9033147)	0.601	4
UniProt:O60763 USO1	5	USO1 [transport vesicle] (R-HSA-6808817) USO1 [ER to Golgi transport vesicle membrane] (R-HSA-2311338) USO1 [Golgi membrane] (R-HSA-2167936) USO1 [microtubule organizing center] (R-HSA-9646385) USO1 [cytosol] (R-HSA-5685737)	0.601	4
UniProt:Q07866 KLC1	3	KLC1 [cytosol] (R-HSA-983284) KLC1(1-420)-ALK(1058-1620) fusion [cytosol] (R-HSA-9711968) KLC1(1-420)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9711978)	0.601	4
UniProt:P54727 RAD23B	2	RAD23B [cytosol] (R-HSA-8850589) RAD23B [nucleoplasm] (R-HSA-62590)	0.601	4
UniProt:Q16543 CDC37	1	CDC37 [cytosol] (R-HSA-1221609)	0.601	4
UniProt:Q9H0B6 KLC2	1	KLC2 [cytosol] (R-HSA-983191)	0.601	4
UniProt:P78563 ADARB1	1	ADARB1 [nucleoplasm] (R-HSA-62915)	0.601	4
IntAct:EBI-26982064 T20			0.598	3
UniProt:O15118 NPC1	1	NPC1 [lysosomal membrane] (R-HSA-5216153)	0.591	3
UniProt:P78362 SRPK2	1	SRPK2 [cytosol] (R-HSA-9729332)	0.59	2
UniProt:P49841 GSK3B	5	GSK3B [nucleoplasm] (R-HSA-2022823) GSK3B [cytosol] (R-HSA-2997551) p-S9-GSK3B [cytosol] (R-HSA-3149577) GSK3B [endoplasmic reticulum lumen] (R-HSA-9931408) GSK3B del304-316 [cytosol] (R-HSA-5339682)	0.59	3
UniProt:O14908 GIPC1	1	GIPC1 [cytoplasm] (R-HSA-9839329)	0.589	2
UniProt:Q8IUC4 RHPN2	1	RHPN2 [cytosol] (R-HSA-5667007)	0.589	2
UniProt:O14920 IKBKB	3	IKBKB [cytosol] (R-HSA-168114) p-S177,S181-IKBKB [cytosol] (R-HSA-202506) IKBKB Q432Pfs*62 [cytosol] (R-HSA-9628518)	0.581	7
IntAct:EBI-26608149 17MER			0.569	5
IntAct:EBI-27028509 20-NT SSRNA			0.558	2
IntAct:EBI-26981901 GTGT			0.558	2
UniProt:P26022 PTX3	3	PTX3 [specific granule lumen] (R-HSA-6799620) PTX3 [extracellular region] (R-HSA-6806290) PTX3 [tertiary granule lumen] (R-HSA-6800932)	0.558	2
UniProt:P37840 SNCA	5	SNCA [cytosol] (R-HSA-5658500) p-S129-SNCA [cytosol] (R-HSA-9836432) Ub-SNCA [cytosol] (R-HSA-5660754) SNCA [extracellular region] (R-HSA-976954) SNCA A30P [cytosol] (R-HSA-5658569)	0.558	2
UniProt:Q9NSK0 KLC4	1	KLC4 [cytosol] (R-HSA-983244)	0.556	3
UniProt:Q14241 ELOA	1	TCEB3 [nucleoplasm] (R-HSA-112421)	0.556	3
UniProt:O15226 NKRF			0.556	3
UniProt:O43318 MAP3K7	10	p-T184,T187-MAP3K7 [cytosol] (R-HSA-202527) MAP3K7 [cytosol] (R-HSA-168156) p-T184,T187-MAP3K7 [endosome membrane] (R-HSA-450332) MAP3K7 [endosome membrane] (R-HSA-450315) p-MAP3K7 [cytosol] (R-HSA-168163) K63polyUb-34,158-TAK1 [cytosol] (R-HSA-5607643) K63polyUb-34,158-p-T178,184,187,S192-TAK1 [cytosol] (R-HSA-5607649) p-T187-MAP3K7 [cytosol] (R-HSA-206014) MAP3K7 [plasma membrane] (R-HSA-9012677) PolyUb-MAP3K7 [cytosol] (R-HSA-6782968)	0.556	4
UniProt:Q93008 USP9X	1	USP9X [cytosol] (R-HSA-870499)	0.556	3
UniProt:P0DTC4 E	9	Ub-3xPalmC-E [virion membrane] (R-COV-9698416) Ub-3xPalmC-E [endocytic vesicle membrane] (R-COV-9698422) Ub-3xPalmC-E [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9698420) Ub-3xPalmC-E [Golgi membrane] (R-COV-9694687) Ub-3xPalmC-E [endoplasmic reticulum membrane] (R-COV-9694465) Ub-3xPalmC-E [endoplasmic reticulum lumen] (R-COV-9694423) 3xPalmC-E [endoplasmic reticulum lumen] (R-COV-9694305) nascent E [endoplasmic reticulum lumen] (R-COV-9694312) N-glycan E [endoplasmic reticulum lumen] (R-COV-9694754)	0.553	3
ChEBI:156271 GALLOCATECHIN GALLATE			0.544	2
UniProt:P61289 PSME3	1	PSME3 [cytosol] (R-HSA-68816)	0.544	3
UniProt:P26196 DDX6	1	DDX6 [cytosol] (R-HSA-430032)	0.537	5
UniProt:Q99848 EBNA1BP2	1	EBNA1BP2 [nucleoplasm] (R-HSA-8869325)	0.527	2
UniProt:Q9NWT1 PK1IP			0.527	2
UniProt:Q5SSJ5 HP1B3			0.527	2
UniProt:Q13823 NOG2			0.527	2
UniProt:Q14692 BMS1	1	BMS1 [nucleoplasm] (R-HSA-6790720)	0.527	3
UniProt:Q9ULW3 ABT1			0.527	3
UniProt:Q96E39 RMXL1			0.527	3
UniProt:Q9Y3I0 RTCB	1	RTCB [nucleoplasm] (R-HSA-5696792)	0.527	2
UniProt:P19784 CSNK2A2	2	CSNK2A2 [cytosol] (R-HSA-201721) CSNK2A2 [nucleoplasm] (R-HSA-6805065)	0.527	2
UniProt:P42766 RPL35	1	RPL35 [cytosol] (R-HSA-72460)	0.527	2
UniProt:Q9NVP1 DDX18			0.527	3
UniProt:P32969 RPL9	1	RPL9 [cytosol] (R-HSA-72492)	0.527	2
UniProt:Q14694 USP10	3	USP10 [nucleoplasm] (R-HSA-3222218) K63polyUb-USP10 [cytosol] (R-HSA-6782986) USP10 [cytosol] (R-HSA-6782974)	0.527	3
UniProt:Q9GZL7 WDR12	1	WDR12 [nucleoplasm] (R-HSA-6791215)	0.527	2
UniProt:Q5T280 SPOUT			0.527	2
UniProt:Q9BRP8 PYM1			0.527	3
UniProt:P46013 KI67			0.527	3
UniProt:P83731 RPL24	1	RPL24 [cytosol] (R-HSA-72434)	0.527	2
UniProt:P62841 RPS15	2	RPS15 [cytosol] (R-HSA-72335) RPS15 [nucleoplasm] (R-HSA-6798706)	0.527	3
UniProt:Q12906 ILF3	3	ILF3 [cytosol] (R-HSA-450564) p-T188,T315-ILF3 [cytosol] (R-HSA-9836381) ILF3 [nucleoplasm] (R-HSA-9760401)	0.527	3
UniProt:Q9NUQ6 SPS2L			0.527	2
UniProt:P27635 RPL10	1	RPL10 [cytosol] (R-HSA-72402)	0.527	3
UniProt:Q8IY37 DHX37	1	DHX37 [nucleoplasm] (R-HSA-6790668)	0.527	2
UniProt:Q9UGR2 Z3H7B			0.527	3
UniProt:Q9NV31 IMP3	1	IMP3 [nucleoplasm] (R-HSA-6790664)	0.527	2
UniProt:Q9H7H0 MET17			0.527	3
UniProt:Q9H6F5 CCD86			0.527	2
UniProt:Q9NQZ2 UTP3	1	UTP3 [nucleoplasm] (R-HSA-6790637)	0.527	2
UniProt:P16402 H1-3	1	HIST1H1D [nucleoplasm] (R-HSA-211241)	0.527	2
UniProt:Q15050 RRS1			0.527	2
UniProt:O00566 MPHOSPH10	1	MPHOSPH10 [nucleoplasm] (R-HSA-6790661)	0.527	2
UniProt:Q8N7H5 PAF1	1	PAF1 [nucleoplasm] (R-HSA-8866689)	0.527	3
UniProt:O00567 NOP56	2	NOP56 [nucleoplasm] (R-HSA-6790696) NOP56 [cytosol] (R-HSA-391293)	0.527	3
UniProt:P35268 RPL22	1	RPL22 [cytosol] (R-HSA-72428)	0.527	2
UniProt:Q9BVJ6 UTP14A	1	UTP14A [nucleoplasm] (R-HSA-6790695)	0.527	2
UniProt:Q9NUD5 ZCHC3			0.527	2
UniProt:O75683 SURF6			0.527	2
UniProt:Q6PK04 CC137			0.527	3
UniProt:Q9UII4 HERC5	1	HERC5 [cytosol] (R-HSA-936553)	0.527	3
UniProt:Q9UKM9 RALY			0.527	2
UniProt:P61254 RPL26	1	RPL26 [cytosol] (R-HSA-72436)	0.527	3
UniProt:Q9UL40 ZN346			0.527	4
UniProt:Q9UN81 LORF1			0.527	2
UniProt:P84098 RPL19	1	RPL19 [cytosol] (R-HSA-72424)	0.527	3
UniProt:O43818 RRP9	1	RRP9 [nucleoplasm] (R-HSA-6790682)	0.527	2
UniProt:Q9Y6M1 IGF2BP2	1	IGF2BP2 [cytosol] (R-HSA-428302)	0.527	2
UniProt:P26368 U2AF2	2	U2AF2 [nucleoplasm] (R-HSA-71987) 5OHK15,276-U2AF2 [nucleoplasm] (R-HSA-9630011)	0.527	2
UniProt:Q52LJ0 FAM98B	1	FAM98B [nucleoplasm] (R-HSA-5696804)	0.527	2
UniProt:Q9UNX4 WDR3	1	WDR3 [nucleoplasm] (R-HSA-6790724)	0.527	2
UniProt:A0AV96 RBM47			0.527	2
UniProt:Q9BQ75 CMS1			0.527	2
UniProt:O95810 CAVN2			0.527	2
UniProt:P08708 RPS17	2	RPS17 [cytosol] (R-HSA-72339) RPS17 [nucleoplasm] (R-HSA-6798719)	0.527	3
UniProt:P46783 RPS10	3	RPS10 [cytosol] (R-HSA-72325) K63polyUb-K138,K139-RPS10 [cytosol] (R-HSA-9948298) RPS10 [nucleoplasm] (R-HSA-6798733)	0.527	2
UniProt:Q9H7B2 RPF2			0.527	2
UniProt:Q7L2E3 DHX30			0.527	2
UniProt:Q9H0A0 NAT10	1	NAT10 [nucleoplasm] (R-HSA-6791008)	0.527	2
UniProt:Q9Y224 RTRAF	1	C14orf166 [nucleoplasm] (R-HSA-5696803)	0.527	2
UniProt:Q659C4 LAR1B			0.527	2
UniProt:Q9H0S4 DDX47	1	DDX47 [nucleoplasm] (R-HSA-6790605)	0.527	2
UniProt:Q9UNX3 RPL26L1	1	RPL26L1 [cytosol] (R-HSA-72438)	0.527	3
UniProt:Q3KQU3 MA7D1			0.527	3
UniProt:Q96BK5 PINX1			0.527	3
UniProt:Q9Y5J1 UTP18	1	UTP18 [nucleoplasm] (R-HSA-6790645)	0.527	2
UniProt:P40429 RPL13A	2	RPL13A [cytosol] (R-HSA-72412) p-RPL13A [cytosol] (R-HSA-156829)	0.527	2
UniProt:Q14137 BOP1	1	BOP1 [nucleoplasm] (R-HSA-6791206)	0.527	4
UniProt:Q9NY12 GAR1	1	GAR1 [nucleoplasm] (R-HSA-6790707)	0.527	2
UniProt:Q9H2U1 DHX36	1	DHX36 [cytosol] (R-HSA-3134862)	0.527	2
UniProt:P62277 RPS13	2	RPS13 [cytosol] (R-HSA-72331) RPS13 [nucleoplasm] (R-HSA-6791198)	0.527	4
UniProt:P62280 RPS11	2	RPS11 [cytosol] (R-HSA-72327) RPS11 [nucleoplasm] (R-HSA-6791212)	0.527	4
UniProt:Q15717 ELAVL1	6	ELAVL1 [nucleoplasm] (R-HSA-450601) p-S158,S221-ELAVL1 [nucleoplasm] (R-HSA-450576) p-S221,S318-ELAVL1 [nucleoplasm] (R-HSA-450532) ELAVL1 [cytosol] (R-HSA-450582) p-S221,S318-ELAVL1 [cytosol] (R-HSA-450448) p-S158,S221-ELAVL1 [cytosol] (R-HSA-450376)	0.527	2
UniProt:O14979 HNRNPDL	1	HNRNPDL [cytosol] (R-HSA-8950323)	0.527	2
UniProt:Q01780 EXOSC10	2	EXOSC10 [nucleoplasm] (R-HSA-6791547) EXOSC10 [nucleolus] (R-HSA-9935809)	0.527	2
UniProt:Q9H6S0 YTHDC2	1	YTHDC2 [nucleoplasm] (R-HSA-9935827)	0.527	3
UniProt:Q9NY61 AATF	1	AATF [cytosol] (R-HSA-205071)	0.527	2
UniProt:Q8WVM0 TFB1M	1	TFB1M [mitochondrial matrix] (R-HSA-1592207)	0.527	2
UniProt:P38646 HSPA9	6	HSPA9 [mitochondrial matrix] (R-HSA-8878802) HSPA9 [mitochondrial inner membrane] (R-HSA-1252206) HSPA9(1-679) [cytosol] (R-HSA-1267964) HSPA9(1-679) [mitochondrial intermembrane space] (R-HSA-1267968) HSPA9 [nucleoplasm] (R-HSA-5252128) HSPA9 [cytosol] (R-HSA-5251993)	0.527	3
UniProt:P11142 HSPA8	10	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.527	3
UniProt:P07910 HNRNPC	3	HNRNPC [nucleoplasm] (R-HSA-71933) SUMO1-K250-HNRNPC [nucleoplasm] (R-HSA-4570543) HNRNPC [cytosol] (R-HSA-9715136)	0.527	2
UniProt:Q12905 ILF2	5	ILF2 [cytosol] (R-HSA-9836392) ILF2 [tertiary granule lumen] (R-HSA-6800995) ILF2 [extracellular region] (R-HSA-6799684) ILF2 [specific granule lumen] (R-HSA-6799611) ILF2 [ficolin-1-rich granule lumen] (R-HSA-6801001)	0.527	3
UniProt:P11021 HSPA5	7	HSPA5 [lumenal side of endoplasmic reticulum membrane] (R-HSA-985498) HSPA5 [endoplasmic reticulum membrane] (R-HSA-351315) HSPA5 [endoplasmic reticulum lumen] (R-HSA-387190) HSPA5 [nucleoplasm] (R-HSA-5252042) HSPA5 [cytosol] (R-HSA-5252115) HSPA5 [plasma membrane] (R-HSA-9922467) HSPA5 [extracellular region] (R-HSA-351322)	0.527	3
UniProt:Q8IY81 FTSJ3	1	FTSJ3 [nucleoplasm] (R-HSA-6791507)	0.527	2
UniProt:O60832 DKC1	1	DKC1 [nucleoplasm] (R-HSA-163102)	0.527	3
UniProt:P61247 RPS3A	2	RPS3A [cytosol] (R-HSA-72373) RPS3A [nucleoplasm] (R-HSA-6791182)	0.527	4
UniProt:Q99873 PRMT1	2	PRMT1 [cytosol] (R-HSA-9632173) PRMT1 [nucleoplasm] (R-HSA-3215140)	0.525	3
IntAct:EBI-26855570 N1541			0.524	3
IntAct:EBI-26967810 55-NT			0.522	3
IntAct:EBI-27159111 S2M			0.522	3
IntAct:EBI-26430259 AUUAAAG			0.522	2
IntAct:EBI-26870678 PS-318			0.464	3
IntAct:EBI-26855521 A85 RNA OLIGO			0.464	2
IntAct:EBI-26855120 H20			0.464	4
UniProt:Q9BYX4 IFIH1	3	IFIH1 [cytosol] (R-HSA-913536) K48polyUb-IFIH1 [cytosol] (R-HSA-3080557) PolyUb-IFIH1 [cytosol] (R-HSA-6782812)	0.463	2

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