Reactome | rbm8A [cytosol]

rbm8A [cytosol]

Stable Identifier

R-DDI-162462

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

cytosol

Synonyms

RBM8A, Q54ME8

Locations in the PathwayBrowser

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Metabolism of RNA (Dictyostelium discoideum)

- Nonsense-Mediated Decay (NMD) (Dictyostelium discoideum)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Dictyostelium discoideum)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Dictyostelium discoideum)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Dictyostelium discoideum)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Dictyostelium discoideum)
        
        Magoh-Y14 complex [cytosol] (Dictyostelium discoideum)
        
        rbm8A [cytosol] (Dictyostelium discoideum)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Dictyostelium discoideum)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Dictyostelium discoideum)
        
        Magoh-Y14 complex [cytosol] (Dictyostelium discoideum)
        
        rbm8A [cytosol] (Dictyostelium discoideum)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Dictyostelium discoideum)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Dictyostelium discoideum)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Dictyostelium discoideum)
        
        Magoh-Y14 complex [cytosol] (Dictyostelium discoideum)
        
        rbm8A [cytosol] (Dictyostelium discoideum)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Dictyostelium discoideum)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Dictyostelium discoideum)
        
        Magoh-Y14 complex [cytosol] (Dictyostelium discoideum)
        
        rbm8A [cytosol] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:Q54ME8

Gene Names

rbm8A

Reference Genes

BioGPS Gene:8625394 rbm8A

dictyBase:DDB_G0286007

ENSEMBL:DDB_G0286007

KEGG Gene (Dictyostelium discoideum):DDB_G0286007 rbm8A

Monarch:8625394 rbm8A

NCBI Gene:8625394 rbm8A

Reference Transcript

RefSeq:XM_632849.1 rbm8A

Participates

as a component of

Magoh-Y14 complex [cytosol] (Dictyostelium discoideum)

Other forms of this molecule

rbm8A [nucleoplasm]

Inferred From

RBM8A [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_637941.1

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