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tor [cytosol]
Stable Identifier
R-DDI-165662
Type
Protein [EntityWithAccessionedSequence]
Species
Dictyostelium discoideum
Compartment
cytosol
Synonyms
MTOR, Q86C65
Locations in the PathwayBrowser
Expand all
Autophagy (Dictyostelium discoideum)
Macroautophagy (Dictyostelium discoideum)
Active MTORC1 binds the ULK1 complex (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
Active MTORC1 phosphorylates ULK1 (Dictyostelium discoideum)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
MTORC1 dissociates from ULK complex (Dictyostelium discoideum)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
Rheb in the MTORC1 complex hydrolyses GTP (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Dictyostelium discoideum)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
Cellular responses to stimuli (Dictyostelium discoideum)
Cellular responses to stress (Dictyostelium discoideum)
Cellular response to starvation (Dictyostelium discoideum)
Amino acids regulate mTORC1 (Dictyostelium discoideum)
RRAGA,B hydrolyzes GTP (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
mTORC1 binds RHEB:GTP (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
Gene expression (Transcription) (Dictyostelium discoideum)
RNA Polymerase II Transcription (Dictyostelium discoideum)
Generic Transcription Pathway (Dictyostelium discoideum)
Transcriptional Regulation by TP53 (Dictyostelium discoideum)
Regulation of TP53 Activity (Dictyostelium discoideum)
Regulation of TP53 Expression and Degradation (Dictyostelium discoideum)
Regulation of TP53 Degradation (Dictyostelium discoideum)
TORC2 complex phosphorylates SGK1 (Dictyostelium discoideum)
TORC2 complex [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
TP53 Regulates Metabolic Genes (Dictyostelium discoideum)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
Immune System (Dictyostelium discoideum)
Adaptive Immune System (Dictyostelium discoideum)
Costimulation by the CD28 family (Dictyostelium discoideum)
CD28 co-stimulation (Dictyostelium discoideum)
CD28 dependent PI3K/Akt signaling (Dictyostelium discoideum)
TORC2 (mTOR) phosphorylates AKT at S473 (Dictyostelium discoideum)
TORC2 complex [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
Signal Transduction (Dictyostelium discoideum)
Intracellular signaling by second messengers (Dictyostelium discoideum)
PIP3 activates AKT signaling (Dictyostelium discoideum)
PTEN Regulation (Dictyostelium discoideum)
Regulation of PTEN gene transcription (Dictyostelium discoideum)
MAF1 translocates to the nucleus (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
mTORC1 phosphorylates MAF1 (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
TORC2 (mTOR) phosphorylates AKT at S473 (Dictyostelium discoideum)
TORC2 complex [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
TORC2 complex phosphorylates SGK1 (Dictyostelium discoideum)
TORC2 complex [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
MTOR signalling (Dictyostelium discoideum)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Dictyostelium discoideum)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
Energy dependent regulation of mTOR by LKB1-AMPK (Dictyostelium discoideum)
AMPK phosphorylates Raptor in the mTORC1 complex (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
Formation of active mTORC1 complex (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
mTORC1 phosphorylates AKT1S1 (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
mTORC1-mediated signalling (Dictyostelium discoideum)
Phosphorylation of 4E-BP1 by activated mTORC1 (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
Signaling by Receptor Tyrosine Kinases (Dictyostelium discoideum)
Signaling by VEGF (Dictyostelium discoideum)
VEGFA-VEGFR2 Pathway (Dictyostelium discoideum)
VEGFR2 mediated vascular permeability (Dictyostelium discoideum)
TORC2 (mTOR) phosphorylates AKT at S473 (Dictyostelium discoideum)
TORC2 complex [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
tor [cytosol] (Dictyostelium discoideum)
External Reference Information
External Reference
UniProt:Q86C65
Gene Names
tor
Reference Genes
BioGPS Gene:8623240 tor
dictyBase:DDB_G0281569
ENSEMBL:DDB_G0281569
KEGG Gene (Dictyostelium discoideum):DDB_G0281569 tor
Monarch:8623240 tor
NCBI Gene:8623240 tor
Reference Transcript
RefSeq:XM_635537.1 tor
Participates
as a component of
TORC2 complex [cytosol] (Dictyostelium discoideum)
mTORC1 [cytosol] (Dictyostelium discoideum)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Dictyostelium discoideum)
Other forms of this molecule
tor [nucleoplasm]
Inferred From
MTOR [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_640629.1
PRO
Q86C65
© 2024
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