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Active mTORC1 complex [lysosomal membrane]
Stable Identifier
R-DDI-165678
Type
Complex
Species
Dictyostelium discoideum
Compartment
lysosomal membrane
Locations in the PathwayBrowser
Expand all
Autophagy (Dictyostelium discoideum)
Macroautophagy (Dictyostelium discoideum)
Active MTORC1 binds the ULK1 complex (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
Active MTORC1 phosphorylates ULK1 (Dictyostelium discoideum)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
Rheb in the MTORC1 complex hydrolyses GTP (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Dictyostelium discoideum)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
Gene expression (Transcription) (Dictyostelium discoideum)
RNA Polymerase II Transcription (Dictyostelium discoideum)
Generic Transcription Pathway (Dictyostelium discoideum)
Transcriptional Regulation by TP53 (Dictyostelium discoideum)
TP53 Regulates Metabolic Genes (Dictyostelium discoideum)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
Signal Transduction (Dictyostelium discoideum)
Intracellular signaling by second messengers (Dictyostelium discoideum)
PIP3 activates AKT signaling (Dictyostelium discoideum)
PTEN Regulation (Dictyostelium discoideum)
Regulation of PTEN gene transcription (Dictyostelium discoideum)
MAF1 translocates to the nucleus (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 phosphorylates MAF1 (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
MTOR signalling (Dictyostelium discoideum)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Dictyostelium discoideum)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
Energy dependent regulation of mTOR by LKB1-AMPK (Dictyostelium discoideum)
AMPK phosphorylates Raptor in the mTORC1 complex (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
Formation of active mTORC1 complex (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 phosphorylates AKT1S1 (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1-mediated signalling (Dictyostelium discoideum)
Phosphorylation of 4E-BP1 by activated mTORC1 (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane] (Dictyostelium discoideum)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane]
(Dictyostelium discoideum)
RHEB:GTP [lysosomal membrane]
(Dictyostelium discoideum)
Participates
as an input of
AMPK phosphorylates Raptor in the mTORC1 complex (Dictyostelium discoideum)
Rheb in the MTORC1 complex hydrolyses GTP (Dictyostelium discoideum)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Dictyostelium discoideum)
Active MTORC1 binds the ULK1 complex (Dictyostelium discoideum)
as a component of
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Dictyostelium discoideum)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Dictyostelium discoideum)
as an output of
Formation of active mTORC1 complex (Dictyostelium discoideum)
This entity regulates
Negatively
MAF1 translocates to the nucleus
(Dictyostelium discoideum)
Inferred From
Active mTORC1 complex [lysosomal membrane]
(Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane]
(Homo sapiens)
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