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About
What is Reactome ?
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Digital Preservation
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RBX1 [cytosol]
Stable Identifier
R-DDI-180582
Type
Protein [EntityWithAccessionedSequence]
Species
Dictyostelium discoideum
Compartment
cytosol
Synonyms
Q54K33
Locations in the PathwayBrowser
Expand all
Cell Cycle (Dictyostelium discoideum)
Cell Cycle, Mitotic (Dictyostelium discoideum)
Mitotic G2-G2/M phases (Dictyostelium discoideum)
G2/M Transition (Dictyostelium discoideum)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Dictyostelium discoideum)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Dictyostelium discoideum)
SCF-FBXL7:PolyUb-AURKA [cytosol] (Dictyostelium discoideum)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SCF-FBXL7 ubiquitinates AURKA (Dictyostelium discoideum)
SCF-FBXL7:AURKA [cytosol] (Dictyostelium discoideum)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SCF-FBXL7:PolyUb-AURKA [cytosol] (Dictyostelium discoideum)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SCF:FBXL7 binds AURKA (Dictyostelium discoideum)
SCF-FBXL7:AURKA [cytosol] (Dictyostelium discoideum)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
Cellular responses to stimuli (Dictyostelium discoideum)
Cellular responses to stress (Dictyostelium discoideum)
Cellular response to chemical stress (Dictyostelium discoideum)
KEAP1-NFE2L2 pathway (Dictyostelium discoideum)
CUL3:RBX1 ubiquitinates KEAP1 (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SESN1,2:ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
ub-KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
NFE2L2 inducers:KEAP1:CUL3:RBX1:NFE2L2 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
MAP1LC3B binds KEAP1 and SQSTM1 (Dictyostelium discoideum)
MAP1LC3B:SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
ub-KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
ub-KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
NFE2L2 inducers:KEAP1:CUL3:RBX1:NFE2L2 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
RBX1:CUL3 dissociates from forming autophagosome (Dictyostelium discoideum)
MAP1LC3B:SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
ub-KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SESN1,SESN1 bind SQSTM1 and KEAP1 (Dictyostelium discoideum)
SESN1,2:ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Dictyostelium discoideum)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Dictyostelium discoideum)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
Immune System (Dictyostelium discoideum)
Adaptive Immune System (Dictyostelium discoideum)
Class I MHC mediated antigen processing & presentation (Dictyostelium discoideum)
Antigen processing: Ubiquitination & Proteasome degradation (Dictyostelium discoideum)
Interaction of E3 with substrate and E2-Ub complex (Dictyostelium discoideum)
Ag-substrate:E3:E2:Ub [cytosol] (Dictyostelium discoideum)
E3 ligases in proteasomal degradation [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
E3 ligases in proteasomal degradation [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
Polyubiquitination of substrate (Dictyostelium discoideum)
E3 ligases in proteasomal degradation [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
E3:K48-polyubiquitinated substrate [cytosol] (Dictyostelium discoideum)
E3 ligases in proteasomal degradation [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
E3:Ub:substrate [cytosol] (Dictyostelium discoideum)
E3 ligases in proteasomal degradation [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
Release of E3 from polyubiquitinated substrate (Dictyostelium discoideum)
E3 ligases in proteasomal degradation [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
E3:K48-polyubiquitinated substrate [cytosol] (Dictyostelium discoideum)
E3 ligases in proteasomal degradation [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
Transfer of Ub from E2 to substrate and release of E2 (Dictyostelium discoideum)
Ag-substrate:E3:E2:Ub [cytosol] (Dictyostelium discoideum)
E3 ligases in proteasomal degradation [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
E3 ligases in proteasomal degradation [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
E3:Ub:substrate [cytosol] (Dictyostelium discoideum)
E3 ligases in proteasomal degradation [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
Metabolism of proteins (Dictyostelium discoideum)
Post-translational protein modification (Dictyostelium discoideum)
Neddylation (Dictyostelium discoideum)
AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Dictyostelium discoideum)
CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Dictyostelium discoideum)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Dictyostelium discoideum)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Dictyostelium discoideum)
NEDD8-CRL1 E3 ligase complex [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Dictyostelium discoideum)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Dictyostelium discoideum)
CRL2 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Dictyostelium discoideum)
CRL2 E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Dictyostelium discoideum)
NEDD8-CRL2 E3 ligase complex [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Dictyostelium discoideum)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Dictyostelium discoideum)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Dictyostelium discoideum)
NEDD8-CUL3:RBX1:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
CAND1 binds cytosolic CRL E3 ubiquitin ligases (Dictyostelium discoideum)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Dictyostelium discoideum)
CRL E3 ubiquitin ligases [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
CRL E3 ubiquitin ligases [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Dictyostelium discoideum)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Dictyostelium discoideum)
CRL E3 ubiquitin ligases [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Dictyostelium discoideum)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Dictyostelium discoideum)
CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Dictyostelium discoideum)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Dictyostelium discoideum)
CRL2 E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Dictyostelium discoideum)
NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Dictyostelium discoideum)
NEDD8-CRL1 E3 ligase complex [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Dictyostelium discoideum)
NEDD8-CRL2 E3 ligase complex [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Dictyostelium discoideum)
NEDD8-CUL3:RBX1:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
NFE2L2 inducers:KEAP1:CUL3:RBX1:NFE2L2 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Dictyostelium discoideum)
CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Dictyostelium discoideum)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Dictyostelium discoideum)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Dictyostelium discoideum)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Dictyostelium discoideum)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Dictyostelium discoideum)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Dictyostelium discoideum)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Dictyostelium discoideum)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 (Dictyostelium discoideum)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:UBXN7 [cytosol] (Dictyostelium discoideum)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
Signal Transduction (Dictyostelium discoideum)
MAPK family signaling cascades (Dictyostelium discoideum)
MAPK1/MAPK3 signaling (Dictyostelium discoideum)
RAF/MAP kinase cascade (Dictyostelium discoideum)
Regulation of RAS by GAPs (Dictyostelium discoideum)
KBTBD7:CUL3:RBX1 ubiquitinates NF1 (Dictyostelium discoideum)
KBTBD7:CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
Signaling by WNT (Dictyostelium discoideum)
TCF dependent signaling in response to WNT (Dictyostelium discoideum)
Degradation of DVL (Dictyostelium discoideum)
DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Dictyostelium discoideum)
DVL:CUL3:KLHL12:RBX1 [cytosol] (Dictyostelium discoideum)
CUL3:KLHL12:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
ub-DVL:CUL3:KLHL12:RBX1 [cytosol] (Dictyostelium discoideum)
CUL3:KLHL12:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
Ubiquitinated DVL is degraded by the proteasome (Dictyostelium discoideum)
CUL3:KLHL12:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
ub-DVL:CUL3:KLHL12:RBX1 [cytosol] (Dictyostelium discoideum)
CUL3:KLHL12:RBX1 [cytosol] (Dictyostelium discoideum)
RBX1 [cytosol] (Dictyostelium discoideum)
External Reference Information
External Reference
UniProt:Q54K33
Reference Genes
BioGPS Gene:8626226
dictyBase:DDB_G0287629
ENSEMBL:DDB_G0287629
KEGG Gene (Dictyostelium discoideum):DDB_G0287629
Monarch:8626226
NCBI Gene:8626226
Reference Transcript
RefSeq:XM_632039.1
Participates
as a component of
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Dictyostelium discoideum)
NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
CUL9:RBX1 [cytosol] (Dictyostelium discoideum)
CRL2 E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
NEDD8-CRL1 E3 ligase complex [cytosol] (Dictyostelium discoideum)
NEDD8-CUL3:RBX1:BTB [cytosol] (Dictyostelium discoideum)
NEDD8-CRL2 E3 ligase complex [cytosol] (Dictyostelium discoideum)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
ub-KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Dictyostelium discoideum)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Dictyostelium discoideum)
CUL3:KLHL12:RBX1 [cytosol] (Dictyostelium discoideum)
KBTBD7:CUL3:RBX1 [cytosol] (Dictyostelium discoideum)
SCF E3 ubiquitin ligase [cytosol] (Dictyostelium discoideum)
RBX1:CUL3:BTB [cytosol] (Dictyostelium discoideum)
Other forms of this molecule
RBX1 [nucleoplasm]
RNF7 (RBX2) [cytosol]
Inferred From
RBX1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_637131.1
PRO
Q54K33
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