Reactome | NCKIPSD [cytosol]

NCKIPSD [cytosol]

Stable Identifier

R-DDI-2197671

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

cytosol

Synonyms

Q54C96

Locations in the PathwayBrowser

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Immune System (Dictyostelium discoideum)

- Innate Immune System (Dictyostelium discoideum)
  - Fcgamma receptor (FCGR) dependent phagocytosis (Dictyostelium discoideum)
    - Regulation of actin dynamics for phagocytic cup formation (Dictyostelium discoideum)
      - (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Dictyostelium discoideum)
        
        Mother filament:branching complex [cytosol] (Dictyostelium discoideum)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Dictyostelium discoideum)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Dictyostelium discoideum)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Dictyostelium discoideum)
        
        NCKIPSD [cytosol] (Dictyostelium discoideum)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Dictyostelium discoideum)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Dictyostelium discoideum)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Dictyostelium discoideum)
        
        NCKIPSD [cytosol] (Dictyostelium discoideum)
      - Detachment of WASP/WAVE (Dictyostelium discoideum)
        
        Mother filament:branching complex [cytosol] (Dictyostelium discoideum)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Dictyostelium discoideum)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Dictyostelium discoideum)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Dictyostelium discoideum)
        
        NCKIPSD [cytosol] (Dictyostelium discoideum)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Dictyostelium discoideum)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Dictyostelium discoideum)
        
        NCKIPSD [cytosol] (Dictyostelium discoideum)

Signal Transduction (Dictyostelium discoideum)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Dictyostelium discoideum)
  - Signaling by Rho GTPases (Dictyostelium discoideum)
    - RHO GTPase Effectors (Dictyostelium discoideum)
      - RHO GTPases Activate WASPs and WAVEs (Dictyostelium discoideum)
        
        (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Dictyostelium discoideum)
        
        Mother filament:branching complex [cytosol] (Dictyostelium discoideum)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Dictyostelium discoideum)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Dictyostelium discoideum)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Dictyostelium discoideum)
        
        NCKIPSD [cytosol] (Dictyostelium discoideum)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Dictyostelium discoideum)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Dictyostelium discoideum)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Dictyostelium discoideum)
        
        NCKIPSD [cytosol] (Dictyostelium discoideum)
        
        Detachment of WASP/WAVE (Dictyostelium discoideum)
        
        Mother filament:branching complex [cytosol] (Dictyostelium discoideum)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Dictyostelium discoideum)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Dictyostelium discoideum)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Dictyostelium discoideum)
        
        NCKIPSD [cytosol] (Dictyostelium discoideum)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Dictyostelium discoideum)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Dictyostelium discoideum)
        
        NCKIPSD [cytosol] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:Q54C96

Reference Genes

BioGPS Gene:8629048

dictyBase:DDB_G0293098

ENSEMBL:DDB_G0293098

KEGG:ddi:DDB_G0293098

Monarch:8629048

NCBI Gene:8629048

UCSC:Q54C96

Reference Transcript

RefSeq:XM_629321.1

Participates

as a component of

Inferred From

SH3 domain proteins [cytosol] (Homo sapiens)

NCKIPSD [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_629323.1