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About
What is Reactome ?
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Team
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Digital Preservation
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CDC42 [plasma membrane]
Stable Identifier
R-DDI-449545
Type
Protein [EntityWithAccessionedSequence]
Species
Dictyostelium discoideum
Compartment
plasma membrane
Synonyms
Q9GPS0
Locations in the PathwayBrowser
Expand all
Immune System (Dictyostelium discoideum)
Adaptive Immune System (Dictyostelium discoideum)
Costimulation by the CD28 family (Dictyostelium discoideum)
CD28 co-stimulation (Dictyostelium discoideum)
CD28 dependent Vav1 pathway (Dictyostelium discoideum)
Activation of PAKs by RAC1 and CDC42 (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
Innate Immune System (Dictyostelium discoideum)
Fcgamma receptor (FCGR) dependent phagocytosis (Dictyostelium discoideum)
Regulation of actin dynamics for phagocytic cup formation (Dictyostelium discoideum)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Dictyostelium discoideum)
Mother filament:branching complex [cytosol] (Dictyostelium discoideum)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Dictyostelium discoideum)
WAVE2, WASP, N-WASP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Dictyostelium discoideum)
WAVE2, WASP, N-WASP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
Autophosphorylation of PAK1 (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
Detachment of WASP/WAVE (Dictyostelium discoideum)
Mother filament:branching complex [cytosol] (Dictyostelium discoideum)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Dictyostelium discoideum)
WAVE2, WASP, N-WASP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
WAVE2, WASP, N-WASP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RAC1 and CDC42 activate PAK1 (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
Signal Transduction (Dictyostelium discoideum)
MAPK family signaling cascades (Dictyostelium discoideum)
MAPK6/MAPK4 signaling (Dictyostelium discoideum)
Activation of PAKs by RAC1 and CDC42 (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
Autophosphorylation of PAK1,2,3 (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Dictyostelium discoideum)
Signaling by Rho GTPases (Dictyostelium discoideum)
RHO GTPase Effectors (Dictyostelium discoideum)
RHO GTPases Activate WASPs and WAVEs (Dictyostelium discoideum)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Dictyostelium discoideum)
Mother filament:branching complex [cytosol] (Dictyostelium discoideum)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Dictyostelium discoideum)
WAVE2, WASP, N-WASP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Dictyostelium discoideum)
WAVE2, WASP, N-WASP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
Detachment of WASP/WAVE (Dictyostelium discoideum)
Mother filament:branching complex [cytosol] (Dictyostelium discoideum)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Dictyostelium discoideum)
WAVE2, WASP, N-WASP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
WAVE2, WASP, N-WASP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RHO GTPases activate IQGAPs (Dictyostelium discoideum)
GTP-bound RAC1 and CDC42 bind IQGAPs (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
IQGAP1 binds CLIP1 and microtubules (Dictyostelium discoideum)
RAC1,CDC42:GTP:IQGAP1 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] (Dictyostelium discoideum)
RAC1,CDC42:GTP:IQGAP1 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
IQGAPs bind CALM1 (Dictyostelium discoideum)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Dictyostelium discoideum)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
IQGAPs bind F-actin, which is inhibited by calmodulin (Dictyostelium discoideum)
RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] (Dictyostelium discoideum)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Dictyostelium discoideum)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RHO GTPases activate PAKs (Dictyostelium discoideum)
Autophosphorylation of PAK1,2,3 (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RAC1 and CDC42 activate PAK1 (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RAC1 and CDC42 activate PAK2 (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RAC1 and CDC42 activate PAK3 (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RHO GTPase cycle (Dictyostelium discoideum)
CDC42 GTPase cycle (Dictyostelium discoideum)
CDC42 GAPs stimulate CDC42 GTPase activity (Dictyostelium discoideum)
CDC42:GDP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
CDC42 GDIs block activation of CDC42 (Dictyostelium discoideum)
CDC42:GDP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
CDC42 GEFs activate CDC42 (Dictyostelium discoideum)
CDC42:GDP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
CDC42 translocates to the endoplasmic reticulum membrane (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RHOG GTPase cycle (Dictyostelium discoideum)
RHOG binds effectors at the plasma membrane (Dictyostelium discoideum)
RHOG plasma membrane effectors [cytosol] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RHOG:GTP:RHOG plasma membrane effectors [plasma membrane] (Dictyostelium discoideum)
RHOG plasma membrane effectors [cytosol] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RHOQ GTPase cycle (Dictyostelium discoideum)
RHOQ binds effectors at the plasma membrane (Dictyostelium discoideum)
RHOQ effectors [cytosol] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RHOQ:GTP:RHOQ effectors [plasma membrane] (Dictyostelium discoideum)
RHOQ effectors [cytosol] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RHOU GTPase cycle (Dictyostelium discoideum)
RHOU binds effectors at the plasma membrane (Dictyostelium discoideum)
RHOU effectors [cytosol] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RHOU:GTP:RHOU effectors [plasma membrane] (Dictyostelium discoideum)
RHOU effectors [cytosol] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RHOV GTPase cycle (Dictyostelium discoideum)
RHOV binds effectors at the plasma membrane (Dictyostelium discoideum)
RHOV effectors [cytosol] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
RHOV:GTP:RHOV effectors [plasma membrane] (Dictyostelium discoideum)
RHOV effectors [cytosol] (Dictyostelium discoideum)
CDC42 [plasma membrane] (Dictyostelium discoideum)
External Reference Information
External Reference
UniProt:Q9GPS0
Reference Genes
BioGPS Gene:8617301
dictyBase:DDB_G0269178
ENSEMBL:DDB_G0269178
KEGG Gene (Dictyostelium discoideum):DDB_G0269178
Monarch:8617301
NCBI Gene:8617301
Reference Transcript
RefSeq:XM_641254.1
Participates
as a candidate of
RHOV effectors [cytosol] (Dictyostelium discoideum)
RHOQ effectors [cytosol] (Dictyostelium discoideum)
RHOG plasma membrane effectors [cytosol] (Dictyostelium discoideum)
RHOJ effectors [cytosol] (Dictyostelium discoideum)
RHOU effectors [cytosol] (Dictyostelium discoideum)
as a component of
CDC42:GDP [plasma membrane] (Dictyostelium discoideum)
CDC42-GDP [plasma membrane] (Dictyostelium discoideum)
CDC42:GTP [plasma membrane] (Dictyostelium discoideum)
Other forms of this molecule
RHOV [plasma membrane]
RHOJ [plasma membrane]
phospho-p-Y254-RHOU [endosome membrane]
phospho-p-Y254-RHOU [plasma membrane]
RHOU [plasma membrane]
RHOQ [plasma membrane]
RHOQ [Golgi-associated vesicle membrane]
CDC42 [endoplasmic reticulum membrane]
CDC42 [cytosol]
Inferred From
CDC42 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
XP_646346.1
PRO
Q9GPS0
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