Reactome | rgaA [cytosol]

rgaA [cytosol]

Stable Identifier

R-DDI-5625975

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

cytosol

Synonyms

IQGAP2, Q54K32

Locations in the PathwayBrowser

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Signal Transduction (Dictyostelium discoideum)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Dictyostelium discoideum)
  - Signaling by Rho GTPases (Dictyostelium discoideum)
    - RHO GTPase Effectors (Dictyostelium discoideum)
      - RHO GTPases activate IQGAPs (Dictyostelium discoideum)
        
        GTP-bound RAC1 and CDC42 bind IQGAPs (Dictyostelium discoideum)
        
        IQGAP [cytosol] (Dictyostelium discoideum)
        
        IQGAP2 dimer [cytosol] (Dictyostelium discoideum)
        
        rgaA [cytosol] (Dictyostelium discoideum)
        
        RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Dictyostelium discoideum)
        
        IQGAP [cytosol] (Dictyostelium discoideum)
        
        IQGAP2 dimer [cytosol] (Dictyostelium discoideum)
        
        rgaA [cytosol] (Dictyostelium discoideum)
        
        IQGAPs bind CALM1 (Dictyostelium discoideum)
        
        RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Dictyostelium discoideum)
        
        IQGAP [cytosol] (Dictyostelium discoideum)
        
        IQGAP2 dimer [cytosol] (Dictyostelium discoideum)
        
        rgaA [cytosol] (Dictyostelium discoideum)
        
        RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Dictyostelium discoideum)
        
        RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Dictyostelium discoideum)
        
        IQGAP [cytosol] (Dictyostelium discoideum)
        
        IQGAP2 dimer [cytosol] (Dictyostelium discoideum)
        
        rgaA [cytosol] (Dictyostelium discoideum)
        
        IQGAPs bind F-actin, which is inhibited by calmodulin (Dictyostelium discoideum)
        
        RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] (Dictyostelium discoideum)
        
        RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Dictyostelium discoideum)
        
        IQGAP [cytosol] (Dictyostelium discoideum)
        
        IQGAP2 dimer [cytosol] (Dictyostelium discoideum)
        
        rgaA [cytosol] (Dictyostelium discoideum)
        
        RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Dictyostelium discoideum)
        
        IQGAP [cytosol] (Dictyostelium discoideum)
        
        IQGAP2 dimer [cytosol] (Dictyostelium discoideum)
        
        rgaA [cytosol] (Dictyostelium discoideum)
        
        RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Dictyostelium discoideum)
        
        RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Dictyostelium discoideum)
        
        IQGAP [cytosol] (Dictyostelium discoideum)
        
        IQGAP2 dimer [cytosol] (Dictyostelium discoideum)
        
        rgaA [cytosol] (Dictyostelium discoideum)
    - RHO GTPase cycle (Dictyostelium discoideum)
      - RAC1 GTPase cycle (Dictyostelium discoideum)
        
        RAC1 binds effectors at the plasma membrane (Dictyostelium discoideum)
        
        RAC1 effectors [cytosol] (Dictyostelium discoideum)
        
        IQGAP2 dimer [cytosol] (Dictyostelium discoideum)
        
        rgaA [cytosol] (Dictyostelium discoideum)
        
        RAC1:GTP:RAC1 effectors [plasma membrane] (Dictyostelium discoideum)
        
        RAC1 effectors [cytosol] (Dictyostelium discoideum)
        
        IQGAP2 dimer [cytosol] (Dictyostelium discoideum)
        
        rgaA [cytosol] (Dictyostelium discoideum)
      - RHOG GTPase cycle (Dictyostelium discoideum)
        
        RHOG binds effectors at the plasma membrane (Dictyostelium discoideum)
        
        RHOG plasma membrane effectors [cytosol] (Dictyostelium discoideum)
        
        IQGAP2 dimer [cytosol] (Dictyostelium discoideum)
        
        rgaA [cytosol] (Dictyostelium discoideum)
        
        RHOG:GTP:RHOG plasma membrane effectors [plasma membrane] (Dictyostelium discoideum)
        
        RHOG plasma membrane effectors [cytosol] (Dictyostelium discoideum)
        
        IQGAP2 dimer [cytosol] (Dictyostelium discoideum)
        
        rgaA [cytosol] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:Q54K32

Gene Names

rgaA

Reference Genes

BioGPS Gene:8626227 rgaA

dictyBase:DDB_G0287585

ENSEMBL:DDB_G0287585

KEGG:ddi:DDB_G0287585 rgaA

Monarch:8626227 rgaA

NCBI Gene:8626227 rgaA

UCSC:Q54K32 rgaA

Reference Transcript

RefSeq:XM_632040.1 rgaA

Participates

as a component of

IQGAP2 dimer [cytosol] (Dictyostelium discoideum)

Other forms of this molecule

rgaA [plasma membrane]

rgaA [secretory granule membrane]

rgaA [cytosol]

Inferred From

IQGAP2 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_637132.1

PRO

Q54K32