Reactome | ctsZ [COPII-coated ER to Golgi transport vesicle]

ctsZ [COPII-coated ER to Golgi transport vesicle]

Stable Identifier

R-DDI-5689727

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

COPII-coated ER to Golgi transport vesicle

Synonyms

(Glc)3(GlcNAc)2(Man)9-CTSZ, Q54R55

Locations in the PathwayBrowser

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Metabolism of proteins (Dictyostelium discoideum)

- Post-translational protein modification (Dictyostelium discoideum)
  - Asparagine N-linked glycosylation (Dictyostelium discoideum)
    - Transport to the Golgi and subsequent modification (Dictyostelium discoideum)
      - ER to Golgi Anterograde Transport (Dictyostelium discoideum)
        
        COPII-mediated vesicle transport (Dictyostelium discoideum)
        
        COPII coat binds TRAPPCII and RAB1:GDP (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        ctsZ [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        ctsZ [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        CSNK1D phosphorylates SEC23 (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        ctsZ [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Dictyostelium discoideum)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        ctsZ [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        Nucleotide exchange on RAB1 (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        ctsZ [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        ctsZ [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)

Vesicle-mediated transport (Dictyostelium discoideum)

- Membrane Trafficking (Dictyostelium discoideum)
  - ER to Golgi Anterograde Transport (Dictyostelium discoideum)
    - COPII-mediated vesicle transport (Dictyostelium discoideum)
      - COPII coat binds TRAPPCII and RAB1:GDP (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        ctsZ [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        ctsZ [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
      - CSNK1D phosphorylates SEC23 (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        ctsZ [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Dictyostelium discoideum)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        ctsZ [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
      - Nucleotide exchange on RAB1 (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        ctsZ [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)
        
        ctsZ [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:Q54R55

Gene Names

ctsZ

Reference Genes

BioGPS Gene:8624061 ctsZ

dictyBase:DDB_G0283401

ENSEMBL:DDB_G0283401

KEGG:ddi:DDB_G0283401 ctsZ

Monarch:8624061 ctsZ

NCBI Gene:8624061 ctsZ

UCSC:Q54R55 ctsZ

Reference Transcript

RefSeq:XM_633944.1 ctsZ

Participates

as a member of

glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Dictyostelium discoideum)

Other forms of this molecule

ctsZ [Golgi lumen]

ctsZ [lysosomal lumen]

ctsZ [endoplasmic reticulum lumen]

ctsZ [ficolin-1-rich granule lumen]

ctsZ [extracellular region]

ctsZ [specific granule lumen]

Inferred From

(Glc)3(GlcNAc)2(Man)9-CTSZ [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)

Modified Residues

Name

N4-(N-acetylamino)glucosyl-L-asparagine (N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue (ChEBI:59084)) at unknown position

Modification

N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-yl group (ChEBI:59084)

PsiMod Name

N4-(N-acetylamino)glucosyl-L-asparagine

PsiMod Definition

A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.

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