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TCEA1 [nucleoplasm]
Stable Identifier
R-DDI-65748
Type
Protein [EntityWithAccessionedSequence]
Species
Dictyostelium discoideum
Compartment
nucleoplasm
Synonyms
Q54YG9
Locations in the PathwayBrowser
Expand all
DNA Repair (Dictyostelium discoideum)
Nucleotide Excision Repair (Dictyostelium discoideum)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Dictyostelium discoideum)
Dual incision in TC-NER (Dictyostelium discoideum)
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Dictyostelium discoideum)
TC-NER incision complex [nucleoplasm] (Dictyostelium discoideum)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Dictyostelium discoideum)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Dictyostelium discoideum)
TC-NER incision complex [nucleoplasm] (Dictyostelium discoideum)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Dictyostelium discoideum)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Dictyostelium discoideum)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Dictyostelium discoideum)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
ERCC2-facilitated RNA Pol II backtracking in TC-NER (Dictyostelium discoideum)
TC-NER pre-incision complex [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
ERCC3-facilitated RNA Pol II backtracking in TC-NER (Dictyostelium discoideum)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
Formation of TC-NER Pre-Incision Complex (Dictyostelium discoideum)
UVSSA:USP7 deubiquitinates ERCC6 (Dictyostelium discoideum)
TC-NER pre-incision complex [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
Gap-filling DNA repair synthesis and ligation in TC-NER (Dictyostelium discoideum)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Dictyostelium discoideum)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Dictyostelium discoideum)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
Gene expression (Transcription) (Dictyostelium discoideum)
RNA Polymerase II Transcription (Dictyostelium discoideum)
Generic Transcription Pathway (Dictyostelium discoideum)
Transcriptional Regulation by TP53 (Dictyostelium discoideum)
TP53 Regulates Transcription of DNA Repair Genes (Dictyostelium discoideum)
CCNK:CDK12 binds RNA Pol II at DNA repair genes (Dictyostelium discoideum)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Dictyostelium discoideum)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Dictyostelium discoideum)
CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes [nucleoplasm] (Dictyostelium discoideum)
CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Dictyostelium discoideum)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Dictyostelium discoideum)
TCEA1 [nucleoplasm] (Dictyostelium discoideum)
External Reference Information
External Reference
UniProt:Q54YG9
Reference Genes
BioGPS Gene:8621441
dictyBase:DDB_G0278241
ENSEMBL:DDB_G0278241
KEGG:ddi:DDB_G0278241
Monarch:8621441
NCBI Gene:8621441
UCSC:Q54YG9
Reference Transcript
RefSeq:XM_637141.1
Participates
as a component of
Elongation complex [nucleoplasm] (Dictyostelium discoideum)
TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Dictyostelium discoideum)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Dictyostelium discoideum)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Dictyostelium discoideum)
TC-NER pre-incision complex [nucleoplasm] (Dictyostelium discoideum)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Dictyostelium discoideum)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Dictyostelium discoideum)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Dictyostelium discoideum)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Dictyostelium discoideum)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Dictyostelium discoideum)
CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Dictyostelium discoideum)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Dictyostelium discoideum)
Inferred From
TCEA1 [nucleoplasm]
(Homo sapiens)
Cross References
PRO
Q54YG9
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