Reactome | WWP2 [cytosol]

WWP2 [cytosol]

Stable Identifier

R-DDI-6807279

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

cytosol

Synonyms

C7G034

Locations in the PathwayBrowser

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Signal Transduction (Dictyostelium discoideum)

- Intracellular signaling by second messengers (Dictyostelium discoideum)
  - PIP3 activates AKT signaling (Dictyostelium discoideum)
    - PTEN Regulation (Dictyostelium discoideum)
      - Regulation of PTEN stability and activity (Dictyostelium discoideum)
        
        NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Dictyostelium discoideum)
        
        NEDD4,STUB1,WWP2 and XIAP [cytosol] (Dictyostelium discoideum)
        
        Homologues of WWP2 [cytosol] (Dictyostelium discoideum)
        
        WWP2 [cytosol] (Dictyostelium discoideum)
- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Dictyostelium discoideum)
  - Signaling by Rho GTPases (Dictyostelium discoideum)
    - RHO GTPase cycle (Dictyostelium discoideum)
      - RHOQ GTPase cycle (Dictyostelium discoideum)
        
        RHOQ binds effectors at the plasma membrane (Dictyostelium discoideum)
        
        RHOQ effectors [cytosol] (Dictyostelium discoideum)
        
        Homologues of WWP2 [cytosol] (Dictyostelium discoideum)
        
        WWP2 [cytosol] (Dictyostelium discoideum)
        
        RHOQ:GTP:RHOQ effectors [plasma membrane] (Dictyostelium discoideum)
        
        RHOQ effectors [cytosol] (Dictyostelium discoideum)
        
        Homologues of WWP2 [cytosol] (Dictyostelium discoideum)
        
        WWP2 [cytosol] (Dictyostelium discoideum)
      - RHOU GTPase cycle (Dictyostelium discoideum)
        
        RHOU binds effectors at the plasma membrane (Dictyostelium discoideum)
        
        RHOU effectors [cytosol] (Dictyostelium discoideum)
        
        Homologues of WWP2 [cytosol] (Dictyostelium discoideum)
        
        WWP2 [cytosol] (Dictyostelium discoideum)
        
        RHOU:GTP:RHOU effectors [plasma membrane] (Dictyostelium discoideum)
        
        RHOU effectors [cytosol] (Dictyostelium discoideum)
        
        Homologues of WWP2 [cytosol] (Dictyostelium discoideum)
        
        WWP2 [cytosol] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:C7G034

Reference Genes

BioGPS Gene:8624873

dictyBase:DDB_G0285063

ENSEMBL:DDB_G0285063

KEGG:ddi:DDB_G0285063

Monarch:8624873

NCBI Gene:8624873

UCSC:C7G034

Reference Transcript

RefSeq:XM_002649091.1

Participates

as a member of

Homologues of WWP2 [cytosol] (Dictyostelium discoideum)

Other forms of this molecule

HUWE1 [ficolin-1-rich granule lumen]

HUWE1 [extracellular region]

HUWE1 [secretory granule lumen]

HUWE1 [cytosol]

NEDD4 [cytosol]

HECW2 [cytosol]

AREL1 [cytosol]

HACE1 [cytosol]

WWP1 [cytosol]

SMURF1 [cytosol]

SMURF2 [cytosol]

NEDD4L [cytosol]

ITCH [cytosol]

Inferred From

WWP2 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_002649137.1

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