Reactome | rps4 [cytosol]

rps4 [cytosol]

Stable Identifier

R-DDI-72375

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

cytosol

Synonyms

RPS4X, P51405

Locations in the PathwayBrowser

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Metabolism of RNA (Dictyostelium discoideum)

- Nonsense-Mediated Decay (NMD) (Dictyostelium discoideum)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Dictyostelium discoideum)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Dictyostelium discoideum)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        40S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rps4 [cytosol] (Dictyostelium discoideum)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        40S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rps4 [cytosol] (Dictyostelium discoideum)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Dictyostelium discoideum)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        40S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rps4 [cytosol] (Dictyostelium discoideum)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        40S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rps4 [cytosol] (Dictyostelium discoideum)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Dictyostelium discoideum)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Dictyostelium discoideum)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        40S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rps4 [cytosol] (Dictyostelium discoideum)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        40S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rps4 [cytosol] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:P51405

Gene Names

rps4

Reference Genes

BioGPS Gene:8618592 rps4

dictyBase:DDB_G0272825

ENSEMBL:DDB_G0272825

KEGG Gene (Dictyostelium discoideum):DDB_G0272825 rps4

Monarch:8618592 rps4

NCBI Gene:8618592 rps4

Reference Transcript

RefSeq:XM_639821.1 rps4

Participates

as a component of

40S ribosomal complex [cytosol] (Dictyostelium discoideum)

Other forms of this molecule

rps4 [nucleoplasm]

rps4 [cytosol]

Inferred From

RPS4X,RPS4Y1,RPS4Y2 [cytosol] (Homo sapiens)

RPS4Y1 [cytosol] (Homo sapiens)

RPS4X [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_644913.1

PRO

P51405

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