Reactome | rpl23 [cytosol]

rpl23 [cytosol]

Stable Identifier

R-DDI-72430

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

cytosol

Synonyms

RPL23, Q54G86

Locations in the PathwayBrowser

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Metabolism of RNA (Dictyostelium discoideum)

- Nonsense-Mediated Decay (NMD) (Dictyostelium discoideum)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Dictyostelium discoideum)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Dictyostelium discoideum)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        60S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rpl23 [cytosol] (Dictyostelium discoideum)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        60S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rpl23 [cytosol] (Dictyostelium discoideum)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Dictyostelium discoideum)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        60S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rpl23 [cytosol] (Dictyostelium discoideum)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        60S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rpl23 [cytosol] (Dictyostelium discoideum)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Dictyostelium discoideum)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Dictyostelium discoideum)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        60S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rpl23 [cytosol] (Dictyostelium discoideum)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        60S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rpl23 [cytosol] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:Q54G86

Gene Names

rpl23

Reference Genes

BioGPS Gene:8627602 rpl23

dictyBase:DDB_G0290315

ENSEMBL:DDB_G0290315

KEGG Gene (Dictyostelium discoideum):DDB_G0290315 rpl23

Monarch:8627602 rpl23

NCBI Gene:8627602 rpl23

Reference Transcript

RefSeq:XM_630705.1 rpl23

Participates

as a component of

Inferred From

RPL23 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_635797.1

PRO

Q54G86

PDB

5ANB, 6QKL, 5ANC, 5AN9

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