Reactome | mybL [nucleoplasm]

mybL [nucleoplasm]

Stable Identifier

R-DDI-83729

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

nucleoplasm

Synonyms

SNAPC4, Q54NA6

Locations in the PathwayBrowser

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Gene expression (Transcription) (Dictyostelium discoideum)

- RNA Polymerase II Transcription (Dictyostelium discoideum)
  - RNA polymerase II transcribes snRNA genes (Dictyostelium discoideum)
    - CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Dictyostelium discoideum)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        SNAPc [nucleoplasm] (Dictyostelium discoideum)
        
        mybL [nucleoplasm] (Dictyostelium discoideum)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        SNAPc [nucleoplasm] (Dictyostelium discoideum)
        
        mybL [nucleoplasm] (Dictyostelium discoideum)
    - Integrator complex processes the 3' end of snRNA (Dictyostelium discoideum)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        SNAPc [nucleoplasm] (Dictyostelium discoideum)
        
        mybL [nucleoplasm] (Dictyostelium discoideum)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        SNAPc [nucleoplasm] (Dictyostelium discoideum)
        
        mybL [nucleoplasm] (Dictyostelium discoideum)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Dictyostelium discoideum)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        SNAPc [nucleoplasm] (Dictyostelium discoideum)
        
        mybL [nucleoplasm] (Dictyostelium discoideum)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        SNAPc [nucleoplasm] (Dictyostelium discoideum)
        
        mybL [nucleoplasm] (Dictyostelium discoideum)
    - RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Dictyostelium discoideum)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        SNAPc [nucleoplasm] (Dictyostelium discoideum)
        
        mybL [nucleoplasm] (Dictyostelium discoideum)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Dictyostelium discoideum)
        
        SNAPc [nucleoplasm] (Dictyostelium discoideum)
        
        mybL [nucleoplasm] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:Q54NA6

Gene Names

mybL

Reference Genes

BioGPS Gene:8625082 mybL

dictyBase:DDB_G0285373

ENSEMBL:DDB_G0285373

KEGG Gene (Dictyostelium discoideum):DDB_G0285373 mybL

Monarch:8625082 mybL

NCBI Gene:8625082 mybL

Reference Transcript

RefSeq:XM_633182.1 mybL

Participates

as a component of

SNAPc [nucleoplasm] (Dictyostelium discoideum)

Inferred From

SNAPC4 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_638274.1

PRO

Q54NA6