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About
What is Reactome ?
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Release Calendar
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Our Logo
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Digital Preservation
Contact us
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p21 RAS:GTP [plasma membrane]
Stable Identifier
R-DME-109783
Type
Complex
Species
Drosophila melanogaster
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
NCAM signaling for neurite out-growth (Drosophila melanogaster)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Cytokine Signaling in Immune system (Drosophila melanogaster)
FLT3 Signaling (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
C-type lectin receptors (CLRs) (Drosophila melanogaster)
CD209 (DC-SIGN) signaling (Drosophila melanogaster)
PAK phosphorylates p21 RAF1 on S338 (Drosophila melanogaster)
p21 RAS:GTP:RAF1 [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:p-S338-RAF1 [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
RAF1 binds p21 RAS:GTP (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:RAF1 [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
SFKs phosphorylates RAF1 on Y340,Y341 (Drosophila melanogaster)
p21 RAS:GTP:p-S338,Y340,Y341-RAF1 [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:p-S338-RAF1 [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
DAP12 interactions (Drosophila melanogaster)
DAP12 signaling (Drosophila melanogaster)
SOS mediated nucleotide exchange of RAS (SHC) (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Fc epsilon receptor (FCERI) signaling (Drosophila melanogaster)
FCERI mediated MAPK activation (Drosophila melanogaster)
SOS mediated nucleotide exchange of RAS (SHC) (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
Intrinsic nucleotide exchange on RAS (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
MAP2K and MAPK activation (Drosophila melanogaster)
Dissociation of RAS:RAF complex (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Dual mechanism MAPK inhibitors bind MAPKs (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
MAP2Ks and MAPKs bind to the activated RAF complex (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
MAP2Ks phosphorylate MAPKs (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
RAF phosphorylates MAP2K dimer (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Negative regulation of MAPK pathway (Drosophila melanogaster)
BRAP autoubiquitinates (Drosophila melanogaster)
p21 RAS:GTP:BRAP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:ub-BRAP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
BRAP binds RAS:GTP (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:BRAP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
PEBP1 binds activated RAF1 (Drosophila melanogaster)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
PP2A dephosphorylates RAF1 (Drosophila melanogaster)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
PP5 dephosphorylates RAF1 S338 (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
RAF activation (Drosophila melanogaster)
"Activator" RAF:YWHAB dimer binds RAS:GTP (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Phosphorylation of RAF (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Raf dimer inhibitors bind RAF heterodimers (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
RAS GEFs promote RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
RAS:GTP binds PI3K (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:PI3K [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Regulation of RAS by GAPs (Drosophila melanogaster)
RAS GAPs bind RAS:GTP (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:RAS GAPs [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
RAS GAPs stimulate RAS GTPase activity (Drosophila melanogaster)
p21 RAS:GTP:RAS GAPs [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (q) signalling events (Drosophila melanogaster)
Gastrin-CREB signalling pathway via PKC and MAPK (Drosophila melanogaster)
EGFR Transactivation by Gastrin (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Signaling by Non-Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by PTK6 (Drosophila melanogaster)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Drosophila melanogaster)
RASA1 binds RAS:GTP (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:RASA1 [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
RASA1 stimulates RAS GTPase activity (Drosophila melanogaster)
p21 RAS:GTP:RASA1 [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
ESR-mediated signaling (Drosophila melanogaster)
Extra-nuclear estrogen signaling (Drosophila melanogaster)
Estrogen-stimulated signaling through PRKCZ (Drosophila melanogaster)
ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Drosophila melanogaster)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Drosophila melanogaster)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by EGFR (Drosophila melanogaster)
GRB2 events in EGFR signaling (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
SHC1 events in EGFR signaling (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Signaling by ERBB2 (Drosophila melanogaster)
GRB2 events in ERBB2 signaling (Drosophila melanogaster)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Signaling by ERBB4 (Drosophila melanogaster)
SHC1 events in ERBB4 signaling (Drosophila melanogaster)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Signaling by FGFR (Drosophila melanogaster)
Signaling by FGFR1 (Drosophila melanogaster)
Downstream signaling of activated FGFR1 (Drosophila melanogaster)
FRS-mediated FGFR1 signaling (Drosophila melanogaster)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
SHC-mediated cascade:FGFR1 (Drosophila melanogaster)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Signaling by FGFR2 (Drosophila melanogaster)
Downstream signaling of activated FGFR2 (Drosophila melanogaster)
FRS-mediated FGFR2 signaling (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
SHC-mediated cascade:FGFR2 (Drosophila melanogaster)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Signaling by FGFR3 (Drosophila melanogaster)
Downstream signaling of activated FGFR3 (Drosophila melanogaster)
FRS-mediated FGFR3 signaling (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
SHC-mediated cascade:FGFR3 (Drosophila melanogaster)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Signaling by FGFR4 (Drosophila melanogaster)
Downstream signaling of activated FGFR4 (Drosophila melanogaster)
FRS-mediated FGFR4 signaling (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
SHC-mediated cascade:FGFR4 (Drosophila melanogaster)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Signaling by NTRKs (Drosophila melanogaster)
Signaling by NTRK1 (TRKA) (Drosophila melanogaster)
Signalling to ERKs (Drosophila melanogaster)
Signalling to RAS (Drosophila melanogaster)
p38MAPK events (Drosophila melanogaster)
Ral-GDS binds to Ras-GTP (Drosophila melanogaster)
Ras-GTP:RalGDS complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Signaling by PDGF (Drosophila melanogaster)
Downstream signal transduction (Drosophila melanogaster)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Signaling by SCF-KIT (Drosophila melanogaster)
Activation of RAS by p-KIT bound SOS1 (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VEGFR2 mediated cell proliferation (Drosophila melanogaster)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Drosophila melanogaster)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
GTP [cytosol]
mature p21 RAS [plasma membrane]
(Drosophila melanogaster)
Participates
as a component of
p21 RAS:GTP:p-S338,Y340,Y341-RAF1 [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:p-S338-RAF1 [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:RAF1 [plasma membrane] (Drosophila melanogaster)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:BRAP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:ub-BRAP [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:RAS GAPs [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:PI3K [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:RASA1 [plasma membrane] (Drosophila melanogaster)
Ras-GTP:RalGDS complex [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
as an input of
RAF1 binds p21 RAS:GTP (Drosophila melanogaster)
"Activator" RAF:YWHAB dimer binds RAS:GTP (Drosophila melanogaster)
BRAP binds RAS:GTP (Drosophila melanogaster)
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Drosophila melanogaster)
RAS GAPs bind RAS:GTP (Drosophila melanogaster)
RAS:GTP binds PI3K (Drosophila melanogaster)
RASA1 binds RAS:GTP (Drosophila melanogaster)
Ral-GDS binds to Ras-GTP (Drosophila melanogaster)
as an output of
Activation of RAS by p-KIT bound SOS1 (Drosophila melanogaster)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Drosophila melanogaster)
SOS mediated nucleotide exchange of RAS (SHC) (Drosophila melanogaster)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Drosophila melanogaster)
RAS GEFs promote RAS nucleotide exchange (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Drosophila melanogaster)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Drosophila melanogaster)
Intrinsic nucleotide exchange on RAS (Drosophila melanogaster)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Drosophila melanogaster)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Drosophila melanogaster)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Inferred From
p21 RAS:GTP [plasma membrane]
(Homo sapiens)
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