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p21 RAS:GDP [plasma membrane]
Stable Identifier
R-DME-109796
Type
Complex
Species
Drosophila melanogaster
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
NCAM signaling for neurite out-growth (Drosophila melanogaster)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Cytokine Signaling in Immune system (Drosophila melanogaster)
FLT3 Signaling (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
DAP12 interactions (Drosophila melanogaster)
DAP12 signaling (Drosophila melanogaster)
SOS mediated nucleotide exchange of RAS (SHC) (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Fc epsilon receptor (FCERI) signaling (Drosophila melanogaster)
FCERI mediated MAPK activation (Drosophila melanogaster)
SOS mediated nucleotide exchange of RAS (SHC) (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
Intrinsic nucleotide exchange on RAS (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
RAS GEFs promote RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
RAS processing (Drosophila melanogaster)
mature p21 RAS binds GDP (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Regulation of RAS by GAPs (Drosophila melanogaster)
RAS GAPs stimulate RAS GTPase activity (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (q) signalling events (Drosophila melanogaster)
Gastrin-CREB signalling pathway via PKC and MAPK (Drosophila melanogaster)
EGFR Transactivation by Gastrin (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Signaling by Non-Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by PTK6 (Drosophila melanogaster)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Drosophila melanogaster)
RASA1 stimulates RAS GTPase activity (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
ESR-mediated signaling (Drosophila melanogaster)
Extra-nuclear estrogen signaling (Drosophila melanogaster)
Estrogen-stimulated signaling through PRKCZ (Drosophila melanogaster)
PRKCZ recruits RAS in response to estrogen stimulation (Drosophila melanogaster)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Drosophila melanogaster)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by EGFR (Drosophila melanogaster)
GRB2 events in EGFR signaling (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
SHC1 events in EGFR signaling (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Signaling by ERBB2 (Drosophila melanogaster)
GRB2 events in ERBB2 signaling (Drosophila melanogaster)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Signaling by ERBB4 (Drosophila melanogaster)
SHC1 events in ERBB4 signaling (Drosophila melanogaster)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Signaling by FGFR (Drosophila melanogaster)
Signaling by FGFR1 (Drosophila melanogaster)
Downstream signaling of activated FGFR1 (Drosophila melanogaster)
FRS-mediated FGFR1 signaling (Drosophila melanogaster)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
SHC-mediated cascade:FGFR1 (Drosophila melanogaster)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Signaling by FGFR2 (Drosophila melanogaster)
Downstream signaling of activated FGFR2 (Drosophila melanogaster)
FRS-mediated FGFR2 signaling (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
SHC-mediated cascade:FGFR2 (Drosophila melanogaster)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Signaling by FGFR3 (Drosophila melanogaster)
Downstream signaling of activated FGFR3 (Drosophila melanogaster)
FRS-mediated FGFR3 signaling (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
SHC-mediated cascade:FGFR3 (Drosophila melanogaster)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Signaling by FGFR4 (Drosophila melanogaster)
Downstream signaling of activated FGFR4 (Drosophila melanogaster)
FRS-mediated FGFR4 signaling (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
SHC-mediated cascade:FGFR4 (Drosophila melanogaster)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Signaling by PDGF (Drosophila melanogaster)
Downstream signal transduction (Drosophila melanogaster)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
Signaling by SCF-KIT (Drosophila melanogaster)
Activation of RAS by p-KIT bound SOS1 (Drosophila melanogaster)
p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
GDP [cytosol]
mature p21 RAS [plasma membrane]
(Drosophila melanogaster)
Participates
as an input of
Activation of RAS by p-KIT bound SOS1 (Drosophila melanogaster)
SOS mediated nucleotide exchange of RAS (SHC) (Drosophila melanogaster)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
PRKCZ recruits RAS in response to estrogen stimulation (Drosophila melanogaster)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Drosophila melanogaster)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Drosophila melanogaster)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Drosophila melanogaster)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Drosophila melanogaster)
Intrinsic nucleotide exchange on RAS (Drosophila melanogaster)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Drosophila melanogaster)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Drosophila melanogaster)
RAS GEFs promote RAS nucleotide exchange (Drosophila melanogaster)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Drosophila melanogaster)
as a component of
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
as an output of
RASA1 stimulates RAS GTPase activity (Drosophila melanogaster)
RAS GAPs stimulate RAS GTPase activity (Drosophila melanogaster)
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Drosophila melanogaster)
mature p21 RAS binds GDP (Drosophila melanogaster)
Inferred From
p21 RAS:GDP [plasma membrane]
(Homo sapiens)
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