Autophosphorylation of DINR

Stable Identifier
R-DME-110440
Type
Reaction [transition]
Species
Drosophila melanogaster
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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Autophosphorylation of DINR
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Binding of a DILP to DINR induces a conformational change leading to autophosphorylation.
Literature References
PubMed ID Title Journal Year
7628438 The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential.

Frasch, M, Schlessinger, J, Tabarini, D, Azpiazu, N, Fernandez, R

EMBO J 1995
Participants
Input
Output
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as an event of
Catalyst Activity

transmembrane receptor protein tyrosine kinase activity of DILP:DINR [plasma membrane]

Physical Entity
DILP:DINR [plasma membrane] (Drosophila melanogaster)
Activity
transmembrane receptor protein tyrosine kinase activity (GO:0004714)
Authored
Jassal, B  (2004-02-11)
Created
Jassal, B  (2004-02-11)
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