Reactome | phospho-Lnk [cytosol]

phospho-Lnk [cytosol]

Stable Identifier

R-DME-112184

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

p-Y629-SH2B2, A0A0B4LHY5

Locations in the PathwayBrowser

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Signal Transduction (Drosophila melanogaster)

- Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
  - Signaling by SCF-KIT (Drosophila melanogaster)
    - Regulation of KIT signaling (Drosophila melanogaster)
      - Phosphorylation of APS (Drosophila melanogaster)
        
        p-APS dimer:p-KIT complex [plasma membrane] (Drosophila melanogaster)
        
        p-APS dimer [cytosol] (Drosophila melanogaster)
        
        phospho-Lnk [cytosol] (Drosophila melanogaster)
      - Recruitment of CBL to KIT (Drosophila melanogaster)
        
        CBL:Grb2/p-APS:p-c-Kit complex [plasma membrane] (Drosophila melanogaster)
        
        Grb2:SOS:p-c-Kit/p-APS:p-c-Kit complex [plasma membrane] (Drosophila melanogaster)
        
        p-APS dimer:p-KIT complex [plasma membrane] (Drosophila melanogaster)
        
        p-APS dimer [cytosol] (Drosophila melanogaster)
        
        phospho-Lnk [cytosol] (Drosophila melanogaster)
        
        Grb2:SOS:p-c-Kit/p-APS:p-c-Kit complex [plasma membrane] (Drosophila melanogaster)
        
        p-APS dimer:p-KIT complex [plasma membrane] (Drosophila melanogaster)
        
        p-APS dimer [cytosol] (Drosophila melanogaster)
        
        phospho-Lnk [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:A0A0B4LHY5

Gene Names

Lnk

Reference Genes

BioGPS Gene:43130 Lnk

CTD Gene:43130 Lnk

ENSEMBL:FBgn0028717

FlyBase:FBgn0028717

KEGG:dme:Dmel_CG17367 Lnk

Monarch:43130 Lnk

NCBI Gene:43130 Lnk

UCSC:A0A0B4LHY5 Lnk

Reference Transcript

RefSeq:NM_001300607.1 Lnk

Other Identifiers

153697_at

1625898_s_at

43130

GO:0005068

GO:0005886

GO:0005938

GO:0007165

GO:0007169

GO:0008284

GO:0008286

GO:0014068

GO:0022414

GO:0030307

GO:0033500

GO:0035556

GO:0035591

GO:0040008

GO:0048010

GO:0051897

GO:0060090

GO:0060180

GO:0070328

GO:0070374

GO:1904263

GO:1904778

Participates

as a component of

p-APS dimer [cytosol] (Drosophila melanogaster)

Other forms of this molecule

Lnk [cytosol]

Inferred From

p-Y629-SH2B2 [cytosol] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 629 (in Homo sapiens)

Coordinate

629

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_001287536.1

ENSEMBL

FBpp0308304, FBtr0339160

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