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phospho-p-T286,T292-MAP2K1 [cytosol]
Stable Identifier
R-DME-112374
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
Q24324
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF-independent MAPK1/3 activation (Drosophila melanogaster)
MAPK3 (ERK1) activation (Drosophila melanogaster)
Inactivation of MAP2K1 by CDK1 (Drosophila melanogaster)
p-2T-MAP2K1 [cytosol] (Drosophila melanogaster)
phospho-p-T286,T292-MAP2K1 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q24324 Dsor1
Gene Names
Dsor1, CG15793
Chain
chain:1-396
Reference Genes
BioGPS Gene:31872 Dsor1
KEGG Gene (Drosophila melanogaster):Dmel_CG15793 Dsor1
Monarch:31872 Dsor1
NCBI Gene:31872 Dsor1
Reference Transcript
RefSeq:NM_078543.4 Dsor1
RefSeq:NM_001298115.1 Dsor1
Other Identifiers
154939_at
1626006_at
31872
GO:0000165
GO:0000166
GO:0000187
GO:0000278
GO:0000793
GO:0002376
GO:0004672
GO:0004674
GO:0004708
GO:0004713
GO:0005515
GO:0005524
GO:0005622
GO:0005634
GO:0005635
GO:0005694
GO:0005737
GO:0005829
GO:0006468
GO:0007095
GO:0007173
GO:0007298
GO:0007362
GO:0007430
GO:0007465
GO:0007623
GO:0008286
GO:0008293
GO:0008340
GO:0008543
GO:0009953
GO:0016301
GO:0016310
GO:0016740
GO:0018108
GO:0019900
GO:0022414
GO:0023052
GO:0030154
GO:0033314
GO:0036211
GO:0042386
GO:0042461
GO:0043226
GO:0045500
GO:0048010
GO:0048856
GO:0048870
GO:0051607
GO:0070371
GO:0071481
GO:0098542
GO:0106310
GO:0140096
Participates
as a member of
p-2T-MAP2K1 [cytosol] (Drosophila melanogaster)
Other forms of this molecule
DSOR1 [cytosol]
phospho-p-S,218, S222,T292 MAP2K1 [cytosol]
phospho-p-S,T-MAP2K2 [cytosol]
phospho-p-S218,S222,T286,T292-MAP2K1 [cytosol]
MAP2K1 [cytosol]
MAP2K2 [cytosol]
phospho-p-S222,S226-MAP2K2 [cytosol]
phospho-p-S218,S222-MAP2K1 [cytosol]
Inferred From
p-T286,T292-MAP2K1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 286 (in Homo sapiens)
Coordinate
286
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at 292 (in Homo sapiens)
Coordinate
292
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_511098.1
,
NP_001285044.1
Flybase
FBgn0010269
PRO
Q24324
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P11346 Raf
20
Phospho PHL [plasma membrane]
(R-DME-205859)
PHL [cytosol]
(R-DME-205713)
RAF1 [cytosol]
(R-DME-167205)
phospho-p-S338,Y340,Y341-RAF1 [cytosol]
(R-DME-5624465)
phospho-p-S338-RAF1 [cytosol]
(R-DME-5624469)
BRAF [cytosol]
(R-DME-167224)
phospho-hyperphosphorylated BRAF [plasma membrane]
(R-DME-5675199)
phospho-hyperphosphorylated RAF1 [plasma membrane]
(R-DME-5675193)
phospho-p-S299,S302,T452,T455,S576 ARAF [cytosol]
(R-DME-5672646)
phospho-p-S445,T599,S602,S729 BRAF [cytosol]
(R-DME-5672676)
phospho-p-S338,Y341,T491,S494,S621 RAF1 [cytosol]
(R-DME-5672664)
phospho-p-S445,S729-BRAF [cytosol]
(R-DME-5672673)
phospho-p-S445,T599,S602,S729 BRAF [plasma membrane]
(R-DME-5672679)
phospho-p-S299,S302,T452,T455,S576 ARAF [plasma membrane]
(R-DME-5672648)
phospho-p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane]
(R-DME-5672665)
phospho-p-S576 ARAF [cytosol]
(R-DME-5672681)
phospho-p-S621-RAF1 [cytosol]
(R-DME-206028)
phospho-p-S214,S576 ARAF [cytosol]
(R-DME-5672639)
phospho-p-S259,S621-RAF1 [cytosol]
(R-DME-109786)
phospho-p-S365,S445,S729 BRAF [cytosol]
(R-DME-5672667)
0.667
5
UniProt:P40417
8
MAPK1 [azurophil granule lumen]
(R-DME-6799225)
MAPK1 [extracellular region]
(R-DME-6806250)
MAPK1 [ficolin-1-rich granule lumen]
(R-DME-6800964)
phospho-p-T185-MAPK1 [cytosol]
(R-DME-9635773)
MAPK1 [nucleoplasm]
(R-DME-199960)
MAPK1 [cytosol]
(R-DME-59282)
phospho-p-T185,Y187-MAPK1 [cytosol]
(R-DME-109853)
phospho-p-T185,Y187-MAPK1 [nucleoplasm]
(R-DME-112354)
0.534
2
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