Reactome | phospho-p-T286,T292-MAP2K1 [cytosol]

phospho-p-T286,T292-MAP2K1 [cytosol]

Stable Identifier

R-DME-112374

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

Q24324

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q24324 Dsor1

Gene Names

Dsor1, CG15793

Chain

chain:1-396

Reference Genes

BioGPS Gene:31872 Dsor1

KEGG Gene (Drosophila melanogaster):Dmel_CG15793 Dsor1

Monarch:31872 Dsor1

NCBI Gene:31872 Dsor1

Reference Transcript

Other Identifiers

154939_at

1626006_at

31872

GO:0000165

GO:0000166

GO:0000187

GO:0000278

GO:0000793

GO:0002376

GO:0004672

GO:0004674

GO:0004708

GO:0004713

GO:0005515

GO:0005524

GO:0005622

GO:0005634

GO:0005635

GO:0005694

GO:0005737

GO:0005829

GO:0006468

GO:0007095

GO:0007173

GO:0007298

GO:0007362

GO:0007430

GO:0007465

GO:0007623

GO:0008286

GO:0008293

GO:0008340

GO:0008543

GO:0009953

GO:0016301

GO:0016310

GO:0016740

GO:0018108

GO:0019900

GO:0022414

GO:0023052

GO:0030154

GO:0033314

GO:0036211

GO:0042386

GO:0042461

GO:0043226

GO:0045500

GO:0048010

GO:0048856

GO:0048870

GO:0051607

GO:0070371

GO:0071481

GO:0098542

GO:0106310

GO:0140096

Participates

as a member of

p-2T-MAP2K1 [cytosol] (Drosophila melanogaster)

Other forms of this molecule

DSOR1 [cytosol]

phospho-p-S,218, S222,T292 MAP2K1 [cytosol]

phospho-p-S,T-MAP2K2 [cytosol]

phospho-p-S218,S222,T286,T292-MAP2K1 [cytosol]

MAP2K1 [cytosol]

MAP2K2 [cytosol]

phospho-p-S222,S226-MAP2K2 [cytosol]

phospho-p-S218,S222-MAP2K1 [cytosol]

Inferred From

p-T286,T292-MAP2K1 [cytosol] (Homo sapiens)

Modified Residues

Name

O-phospho-L-threonine at 286 (in Homo sapiens)

Coordinate

286

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Name

O-phospho-L-threonine at 292 (in Homo sapiens)

Coordinate

292

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

NP_511098.1, NP_001285044.1

Flybase

FBgn0010269

PRO

Q24324

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P11346 Raf	20	Phospho PHL [plasma membrane] (R-DME-205859) PHL [cytosol] (R-DME-205713) RAF1 [cytosol] (R-DME-167205) phospho-p-S338,Y340,Y341-RAF1 [cytosol] (R-DME-5624465) phospho-p-S338-RAF1 [cytosol] (R-DME-5624469) BRAF [cytosol] (R-DME-167224) phospho-hyperphosphorylated BRAF [plasma membrane] (R-DME-5675199) phospho-hyperphosphorylated RAF1 [plasma membrane] (R-DME-5675193) phospho-p-S299,S302,T452,T455,S576 ARAF [cytosol] (R-DME-5672646) phospho-p-S445,T599,S602,S729 BRAF [cytosol] (R-DME-5672676) phospho-p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (R-DME-5672664) phospho-p-S445,S729-BRAF [cytosol] (R-DME-5672673) phospho-p-S445,T599,S602,S729 BRAF [plasma membrane] (R-DME-5672679) phospho-p-S299,S302,T452,T455,S576 ARAF [plasma membrane] (R-DME-5672648) phospho-p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane] (R-DME-5672665) phospho-p-S576 ARAF [cytosol] (R-DME-5672681) phospho-p-S621-RAF1 [cytosol] (R-DME-206028) phospho-p-S214,S576 ARAF [cytosol] (R-DME-5672639) phospho-p-S259,S621-RAF1 [cytosol] (R-DME-109786) phospho-p-S365,S445,S729 BRAF [cytosol] (R-DME-5672667)	0.667	5
UniProt:P40417	8	MAPK1 [azurophil granule lumen] (R-DME-6799225) MAPK1 [extracellular region] (R-DME-6806250) MAPK1 [ficolin-1-rich granule lumen] (R-DME-6800964) phospho-p-T185-MAPK1 [cytosol] (R-DME-9635773) MAPK1 [nucleoplasm] (R-DME-199960) MAPK1 [cytosol] (R-DME-59282) phospho-p-T185,Y187-MAPK1 [cytosol] (R-DME-109853) phospho-p-T185,Y187-MAPK1 [nucleoplasm] (R-DME-112354)	0.534	2

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