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About
What is Reactome ?
News
Team
Scientific Advisory Board
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Editorial Calendar
Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
DOIs
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ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
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Analysis Data
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Integrin alpha2bbeta3 [plasma membrane]
Stable Identifier
R-DME-114514
Type
Complex
Species
Drosophila melanogaster
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Drosophila melanogaster)
ECM proteoglycans (Drosophila melanogaster)
VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3 (Drosophila melanogaster)
Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
VTN:Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin cell surface interactions (Drosophila melanogaster)
Interaction of integrin alphaIIb beta 3 with THBS1 (Thrombospondin-1) (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIbbeta3:THBS1 [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Interaction of integrin alphaIIbbeta3 with von Willebrand factor (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIbbeta3:VWF multimer [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Hemostasis (Drosophila melanogaster)
Platelet activation, signaling and aggregation (Drosophila melanogaster)
Platelet Aggregation (Plug Formation) (Drosophila melanogaster)
Integrin signaling (Drosophila melanogaster)
Activated integrin alphaIIb beta3 binds SHC1 (Drosophila melanogaster)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Autophosphorylation of SRC (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:SRC [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Clustering of Integrin alphaIIb beta3 complexes (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Dephosphorylation of inactive SRC by PTPB1 (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:Inactive (p-Y530)-SRC [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:SRC [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3 activation (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Interaction of integrin alphaIIb beta3 with Fibrinogen (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Release of CSK from SRC (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:Inactive (p-Y530)-SRC [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Drosophila melanogaster)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
SHC1 dissociates from integrin alphaIIb beta3 (Drosophila melanogaster)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
SYK activation by SRC (Drosophila melanogaster)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
SYK binds to integrin alphaIIb beta3 (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Response to elevated platelet cytosolic Ca2+ (Drosophila melanogaster)
Platelet degranulation (Drosophila melanogaster)
Surface deployment of platelet alpha granule membrane components (Drosophila melanogaster)
Platelet alpha granule membrane components that are released on degranulation [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Integrin signaling (Drosophila melanogaster)
Activated integrin alphaIIb beta3 binds SHC1 (Drosophila melanogaster)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Autophosphorylation of SRC (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:SRC [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Clustering of Integrin alphaIIb beta3 complexes (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Dephosphorylation of inactive SRC by PTPB1 (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:Inactive (p-Y530)-SRC [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:SRC [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3 activation (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Interaction of integrin alphaIIb beta3 with Fibrinogen (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Release of CSK from SRC (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:Inactive (p-Y530)-SRC [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Drosophila melanogaster)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
SHC1 dissociates from integrin alphaIIb beta3 (Drosophila melanogaster)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
SYK activation by SRC (Drosophila melanogaster)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
SYK binds to integrin alphaIIb beta3 (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Drosophila melanogaster)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
MAP2K and MAPK activation (Drosophila melanogaster)
Dissociation of RAS:RAF complex (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Dual mechanism MAPK inhibitors bind MAPKs (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
MAP2Ks and MAPKs bind to the activated RAF complex (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
MAP2Ks phosphorylate MAPKs (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
RAF phosphorylates MAP2K dimer (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Focal Adhesion/Focal contacts [plasma membrane] (Drosophila melanogaster)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Drosophila melanogaster)
Focal complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
Integrin alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Homologues of ITGB3 [plasma membrane]
(Drosophila melanogaster)
if [plasma membrane]
(Drosophila melanogaster)
Participates
as a component of
Integrin alphaIIb beta3:Inactive (p-Y530)-SRC [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:SRC [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIbbeta3:THBS1 [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIbbeta3:VWF multimer [plasma membrane] (Drosophila melanogaster)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Drosophila melanogaster)
as an input of
Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding (Drosophila melanogaster)
Interaction of integrin alphaIIb beta 3 with THBS1 (Thrombospondin-1) (Drosophila melanogaster)
Interaction of integrin alphaIIbbeta3 with von Willebrand factor (Drosophila melanogaster)
as a member of
Platelet alpha granule membrane components that are released on degranulation [plasma membrane] (Drosophila melanogaster)
Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Drosophila melanogaster)
Integrins [plasma membrane] (Drosophila melanogaster)
Inferred From
Integrin alpha2bbeta3 [plasma membrane]
(Homo sapiens)
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