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UBI-P63E 12 [cytosol]
Stable Identifier
R-DME-1221561
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
ubiquitin 12
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Circadian Clock pathway (Drosophila melanogaster)
Degradation of CRY (Drosophila melanogaster)
Cytosolic CRY is degraded by the 26S proteasome (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
UBI-P63E:CRY:JET [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
Cytosolic JET binds to CRY, facilitating its ubiquitination (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
UBI-P63E:CRY:JET [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
Degradation of PER (Drosophila melanogaster)
Cytosolic PER is degraded by the 26S proteasome (Drosophila melanogaster)
SLMB:UBI-P63E:Phospho (multi-site 1) PER:DCO [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
SLMB binds phosphorylated cytosolic PER, facilitating its ubiquitination (Drosophila melanogaster)
SLMB:UBI-P63E:Phospho (multi-site 1) PER:DCO [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
Degradation of TIM (Drosophila melanogaster)
Cytosolic TIM is degraded by the 26S proteasome (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
UBI-P63E:TIM:JET [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
JET binds cytosolic TIM, facilitating its ubiquitination (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
UBI-P63E:TIM:JET [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
Hedgehog pathway (Drosophila melanogaster)
N-HH ligand not bound to PTC receptor complex (Drosophila melanogaster)
Ubiquitination and proteolysis of phosphorylated CI (Drosophila melanogaster)
SLMB binds to and ubiquitinates phosphorylated CI (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF:COS:Phospho (16 sites) CI:UBI-P63E:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
Ubiquitinated and phosphorylated CI is partially degraded by the proteasome complex (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF:COS:Phospho (16 sites) CI:UBI-P63E:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
Imd pathway (Drosophila melanogaster)
Activation of the IkappaB kinase complex, KEY:IRD5 dimer:KEY (Drosophila melanogaster)
Activated TAK1 kinase is autophosphorylated (Drosophila melanogaster)
UEV1A:BEN:IAP2:UBI-P63E:TAB2:Phospho TAK1 [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
UEV1A:BEN:IAP2:UBI-P63E:TAB2:TAK1 [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
Activated phosphorylated TAK1 kinase phosphorylates and activates IRD5 (Drosophila melanogaster)
UEV1A:BEN:IAP2:UBI-P63E:TAB2:Phospho TAK1 [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
HEP is phosphorylated and activated by Phospho TAK1:TAB2 kinase complex (Drosophila melanogaster)
UEV1A:BEN:IAP2:UBI-P63E:TAB2:Phospho TAK1 [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
IAP2:BEN:UEV1A E3 ligase complex auto-ubiquitinates (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
UEV1A:BEN:IAP2:UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
TAB2 binds to ubiquitinated IAP2:BEN:UEV1A E3 ligase complex and activates TAK1 kinase (Drosophila melanogaster)
UEV1A:BEN:IAP2:UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
UEV1A:BEN:IAP2:UBI-P63E:TAB2:TAK1 [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
Wingless pathway (Drosophila melanogaster)
WG ligand not bound to FZ receptors (Drosophila melanogaster)
Ubiquitination and degradation of phosphorylated ARM (Drosophila melanogaster)
Dissociation of free ubiquitinated and phosphorylated ARM from SLMB and the 'destruction complex' (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
UBI-P63E:Phospho (4 sites) ARM [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
Ubiquitinated and phosphorylated ARM binds to and is degraded by the proteasome complex (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
UBI-P63E:Phospho (4 sites) ARM [cytosol] (Drosophila melanogaster)
UBI-P63E [cytosol] (Drosophila melanogaster)
UBI-P63E 12 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P18101 RpL40
Gene Names
RpL40, Ubi-f, UBI-F52, CG2960
Chain
chain:1-76, chain:77-128
Reference Genes
BioGPS Gene:33629 RpL40
CTD Gene:33629 RpL40
KEGG Gene (Drosophila melanogaster):Dmel_CG2960 RpL40
Monarch:33629 RpL40
NCBI Gene:33629 RpL40
Reference Transcript
RefSeq:NM_001273089.2 RpL40
RefSeq:NM_057428.4 RpL40
Other Identifiers
143397_at
1633277_at
33629
GO:0002181
GO:0003735
GO:0005198
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0005840
GO:0006412
GO:0006511
GO:0008152
GO:0016567
GO:0019941
GO:0022625
GO:0022627
GO:0030163
GO:0031386
GO:0031625
GO:0036211
GO:0043226
GO:1990904
Participates
as a member of
UBI-P63E [cytosol] (Drosophila melanogaster)
Cross References
RefSeq
NP_476776.1
,
NP_001260018.1
Flybase
FBgn0003941
PRO
P18101
PDB
6XU8
,
6XU7
,
6XU6
,
4V6W
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