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phospho-Usp8 [cytosol]
Stable Identifier
R-DME-1358714
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
p-T945-USP8, Q9VDD8
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by ERBB2 (Drosophila melanogaster)
Downregulation of ERBB2 signaling (Drosophila melanogaster)
Downregulation of ERBB2:ERBB3 signaling (Drosophila melanogaster)
Deubiquitination of RNF41 by P-USP8 (Drosophila melanogaster)
Ub-RNF41:p-USP8 [cytosol] (Drosophila melanogaster)
phospho-Usp8 [cytosol] (Drosophila melanogaster)
phospho-Usp8 [cytosol] (Drosophila melanogaster)
Phosphorylation of USP8 by P-AKT (Drosophila melanogaster)
phospho-Usp8 [cytosol] (Drosophila melanogaster)
Ubiquitinated RNF41 binds P-USP8 (Drosophila melanogaster)
Ub-RNF41:p-USP8 [cytosol] (Drosophila melanogaster)
phospho-Usp8 [cytosol] (Drosophila melanogaster)
phospho-Usp8 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VDD8
Gene Names
Usp8
Reference Genes
BioGPS Gene:42509 Usp8
ENSEMBL:FBgn0038862
Flybase:FBgn0038862
Monarch:42509 Usp8
NCBI Gene:42509 Usp8
UCSC:Q9VDD8 Usp8
Reference Transcript
RefSeq:NM_142691.2 Usp8
Other Identifiers
141593_at
1630825_at
42509
GO:0001921
GO:0003824
GO:0004843
GO:0005515
GO:0005829
GO:0006508
GO:0006511
GO:0008233
GO:0008234
GO:0008587
GO:0016322
GO:0016579
GO:0016787
GO:0023052
GO:0030154
GO:0030163
GO:0036211
GO:0045880
GO:0048856
GO:0090263
GO:0140096
GO:1905166
Participates
as an output of
Deubiquitination of RNF41 by P-USP8 (Drosophila melanogaster)
Phosphorylation of USP8 by P-AKT (Drosophila melanogaster)
as an input of
Ubiquitinated RNF41 binds P-USP8 (Drosophila melanogaster)
as a component of
Ub-RNF41:p-USP8 [cytosol] (Drosophila melanogaster)
Other forms of this molecule
Usp8 [cytosol]
Inferred From
p-T945-USP8 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 945 (in Homo sapiens)
Coordinate
945
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_650948.2
Flybase
FBgn0038862
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P91682 smo
7
SMO [plasma membrane]
(R-DME-206086)
Phospho (3 sites) SMO [plasma membrane]
(R-DME-206009)
Phospho (9 sites) SMO [plasma membrane]
(R-DME-205802)
smo [ciliary membrane]
(R-DME-5624094)
smo [ciliary tip]
(R-DME-5610419)
smo [endocytic vesicle membrane]
(R-DME-5610422)
phospho-smo [ciliary membrane]
(R-DME-5632528)
0.656
4
UniProt:P07764
6
ALDOA [platelet alpha granule lumen]
(R-DME-349738)
ALDOC [tertiary granule lumen]
(R-DME-6801526)
ALDOC [secretory granule lumen]
(R-DME-6801483)
ALDOA [extracellular region]
(R-DME-349735)
ALDOC [ficolin-1-rich granule lumen]
(R-DME-6801464)
ALDOB [cytosol]
(R-DME-70339)
0.462
2
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