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fzy [cytosol]
Stable Identifier
R-DME-141412
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
CDC20, Q24044
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle Checkpoints (Drosophila melanogaster)
Mitotic Spindle Checkpoint (Drosophila melanogaster)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Drosophila melanogaster)
Inactivation of APC/C via CDC20 sequestration (Drosophila melanogaster)
MAD2*CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Inactivation of APC/C via direct inhibition of the APC/C complex (Drosophila melanogaster)
Binding of the MCC complex to the APC/C complex (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Formation of the MCC complex (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
M Phase (Drosophila melanogaster)
Mitotic Metaphase and Anaphase (Drosophila melanogaster)
Mitotic Anaphase (Drosophila melanogaster)
Separation of Sister Chromatids (Drosophila melanogaster)
Degradation of multiubiquitinated Securin (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Drosophila melanogaster)
CDC20:p-APC/C:PTTG1 [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Regulation of mitotic cell cycle (Drosophila melanogaster)
APC/C-mediated degradation of cell cycle proteins (Drosophila melanogaster)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Drosophila melanogaster)
Association of cell cycle proteins with the APC/C:Cdh1 complex (Drosophila melanogaster)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Degradation of multiubiquitinated cell cycle proteins (Drosophila melanogaster)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Drosophila melanogaster)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Drosophila melanogaster)
APC/C:Cdc20 mediated degradation of mitotic proteins (Drosophila melanogaster)
APC/C:Cdc20 mediated degradation of Cyclin B (Drosophila melanogaster)
Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Degradation of multiubiquitinated Cyclin B (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Drosophila melanogaster)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Drosophila melanogaster)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Drosophila melanogaster)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
APC/C:Cdc20 mediated degradation of Securin (Drosophila melanogaster)
Degradation of multiubiquitinated Securin (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Drosophila melanogaster)
CDC20:p-APC/C:PTTG1 [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Drosophila melanogaster)
APC-Cdc20 mediated degradation of Nek2A (Drosophila melanogaster)
Association of Nek2A with MCC:APC/C (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Nek2A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Degradation of multiubiquitinated Nek2A (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Multiubiquitinated Nek2A [cytosol] (Drosophila melanogaster)
Nek2A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Multiubiquitination of Nek2A (Drosophila melanogaster)
Multiubiquitinated Nek2A [cytosol] (Drosophila melanogaster)
Nek2A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Nek2A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Drosophila melanogaster)
Association of Cyclin A with the APC/C (Drosophila melanogaster)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Degradation multiubiquitinated Cyclin A (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Drosophila melanogaster)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Drosophila melanogaster)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Drosophila melanogaster)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Drosophila melanogaster)
Dissociation of Cdc20 from APC/C complex (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Regulation of APC/C activators between G1/S and early anaphase (Drosophila melanogaster)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Drosophila melanogaster)
Inactivation of APC/C via CDC20 sequestration (Drosophila melanogaster)
MAD2*CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Inactivation of APC/C via direct inhibition of the APC/C complex (Drosophila melanogaster)
Binding of the MCC complex to the APC/C complex (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Formation of the MCC complex (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
SCF-beta-TrCP mediated degradation of Emi1 (Drosophila melanogaster)
Ubiquitination of Emi1 by SCF-beta-TrCP (Drosophila melanogaster)
SCF-associated multiubiquitinated Emi1complexes [cytosol] (Drosophila melanogaster)
SCF-beta-TrCP:phospho-Emi1 complexes [cytosol] (Drosophila melanogaster)
phospho-Emi1:Cdc20/Cdh1 complexes [cytosol] (Drosophila melanogaster)
phospho-Emi1(Ser 145, Ser 149):Cdc20/Cdh1 complexes [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
phospho-Emi1(Ser 182):Cdc20/Cdh1:complexes [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
SCF-beta-TrCP:phospho-Emi1 complexes [cytosol] (Drosophila melanogaster)
phospho-Emi1:Cdc20/Cdh1 complexes [cytosol] (Drosophila melanogaster)
phospho-Emi1(Ser 145, Ser 149):Cdc20/Cdh1 complexes [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
phospho-Emi1(Ser 182):Cdc20/Cdh1:complexes [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Class I MHC mediated antigen processing & presentation (Drosophila melanogaster)
Antigen processing: Ubiquitination & Proteasome degradation (Drosophila melanogaster)
Interaction of E3 with substrate and E2-Ub complex (Drosophila melanogaster)
Ag-substrate:E3:E2:Ub [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Polyubiquitination of substrate (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
E3:K48-polyubiquitinated substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
E3:Ub:substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Release of E3 from polyubiquitinated substrate (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
E3:K48-polyubiquitinated substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
Transfer of Ub from E2 to substrate and release of E2 (Drosophila melanogaster)
Ag-substrate:E3:E2:Ub [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
E3:Ub:substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzy [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q24044
Gene Names
fzy
Reference Genes
BioGPS Gene:34968 fzy
CTD Gene:34968 fzy
ENSEMBL:FBgn0001086
Flybase:FBgn0001086
KEGG Gene (Drosophila melanogaster):Dmel_CG4274 fzy
Monarch:34968 fzy
NCBI Gene:34968 fzy
UCSC:Q24044 fzy
Reference Transcript
RefSeq:NM_058153.4 fzy
Other Identifiers
155082_at
1636341_at
34968
GO:0000278
GO:0000776
GO:0005515
GO:0005622
GO:0005634
GO:0005680
GO:0005694
GO:0005737
GO:0005813
GO:0005815
GO:0005819
GO:0005856
GO:0007096
GO:0007144
GO:0007147
GO:0010997
GO:0022414
GO:0030162
GO:0030163
GO:0030718
GO:0031145
GO:0032991
GO:0036211
GO:0043226
GO:0060547
GO:0097027
GO:0097150
GO:0098772
GO:0140013
GO:0140014
GO:1904668
GO:1905786
GO:1990757
Participates
as an input of
Inactivation of APC/C via CDC20 sequestration (Drosophila melanogaster)
Formation of the MCC complex (Drosophila melanogaster)
as a component of
MAD2*CDC20 complex [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Drosophila melanogaster)
as an output of
Dissociation of Cdc20 from APC/C complex (Drosophila melanogaster)
as a member of
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
Other forms of this molecule
fzy [nucleoplasm]
Inferred From
CDC20 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_477501.1
Flybase
FBgn0001086
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P14785
6
CycA [nucleoplasm]
(R-DME-6783099)
CycA [nucleoplasm]
(R-DME-6783068)
CycA [cytosol]
(R-DME-157444)
CycA [cytosol]
(R-DME-157446)
CycA [nucleoplasm]
(R-DME-68891)
CycA [nucleoplasm]
(R-DME-68905)
0.553
2
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