Reactome | Dredd [cytosol]

Dredd [cytosol]

Stable Identifier

R-DME-141639-5

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

CASP9(331-416), Q8IRY7

Locations in the PathwayBrowser

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Programmed Cell Death (Drosophila melanogaster)

- Apoptosis (Drosophila melanogaster)
  - Intrinsic Pathway for Apoptosis (Drosophila melanogaster)
    - Apoptotic factor-mediated response (Drosophila melanogaster)
      - Cytochrome c-mediated apoptotic response (Drosophila melanogaster)
        
        Activation of caspases through apoptosome-mediated cleavage (Drosophila melanogaster)
        
        Cleavage of Procaspase-3 by the apoptosome (Drosophila melanogaster)
        
        Apoptosome [cytosol] (Drosophila melanogaster)
        
        Cleaved Caspase-9 [cytosol] (Drosophila melanogaster)
        
        Homologues of CASP9(331-416) [cytosol] (Drosophila melanogaster)
        
        Dredd [cytosol] (Drosophila melanogaster)
        
        Cleaved Caspase-9 [cytosol] (Drosophila melanogaster)
        
        Homologues of CASP9(331-416) [cytosol] (Drosophila melanogaster)
        
        Dredd [cytosol] (Drosophila melanogaster)
        
        Formation of apoptosome (Drosophila melanogaster)
        
        Cleavage of Procaspase‑9 to caspase‑9 (Drosophila melanogaster)
        
        Apoptosome [cytosol] (Drosophila melanogaster)
        
        Cleaved Caspase-9 [cytosol] (Drosophila melanogaster)
        
        Homologues of CASP9(331-416) [cytosol] (Drosophila melanogaster)
        
        Dredd [cytosol] (Drosophila melanogaster)
        
        Regulation of the apoptosome activity (Drosophila melanogaster)
        
        XIAP binds CASP9 (Drosophila melanogaster)
        
        Apoptosome [cytosol] (Drosophila melanogaster)
        
        Cleaved Caspase-9 [cytosol] (Drosophila melanogaster)
        
        Homologues of CASP9(331-416) [cytosol] (Drosophila melanogaster)
        
        Dredd [cytosol] (Drosophila melanogaster)
        
        XIAP:apoptosome [cytosol] (Drosophila melanogaster)
        
        Apoptosome [cytosol] (Drosophila melanogaster)
        
        Cleaved Caspase-9 [cytosol] (Drosophila melanogaster)
        
        Homologues of CASP9(331-416) [cytosol] (Drosophila melanogaster)
        
        Dredd [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q8IRY7 Dredd

Gene Names

Dredd, DCP2, CG7486

Chain

propeptide:1-242, chain:243-400, propeptide:401-410, chain:411-494

Reference Genes

BioGPS Gene:31011 Dredd

CTD Gene:31011 Dredd

KEGG:dme:Dmel_CG7486 Dredd

Monarch:31011 Dredd

NCBI Gene:31011 Dredd

UCSC:Q8IRY7 Dredd

Reference Transcript

Other Identifiers

152345_at

1639071_a_at

31011

GO:0002230

GO:0002376

GO:0003824

GO:0004175

GO:0004197

GO:0005515

GO:0005737

GO:0005829

GO:0006508

GO:0006915

GO:0006952

GO:0006955

GO:0006963

GO:0006964

GO:0007291

GO:0008047

GO:0008234

GO:0008656

GO:0012501

GO:0016485

GO:0016787

GO:0022414

GO:0043067

GO:0043069

GO:0043525

GO:0045087

GO:0045089

GO:0048856

GO:0048935

GO:0050829

GO:0051604

GO:0061057

GO:0097153

GO:0097194

GO:0097200

GO:0098542

GO:0098772

GO:0140096

Participates

as a member of

Homologues of CASP9(331-416) [cytosol] (Drosophila melanogaster)

Other forms of this molecule

DREDD [cytosol]

Dredd [cytosol]

phospho-Dredd [cytosol]

Dredd [cytosol]

Inferred From

CASP9(331-416) [cytosol] (Homo sapiens)

Cross References

ENSEMBL

FBgn0020381, FBtr0114560, FBpp0113052

IntEnz

3.4.22.61

FlyBase

FBgn0020381

PRO

Q8IRY7

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9V3B4 Fadd	2	BG4 [cytosol] (R-DME-205887) Fadd [cytosol] (R-DME-54639)	0.502	2