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RHEB [lysosomal membrane]
Stable Identifier
R-DME-165190
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
lysosomal membrane
Synonyms
Q9VND8
Locations in the PathwayBrowser
Expand all
Autophagy (Drosophila melanogaster)
Macroautophagy (Drosophila melanogaster)
Active MTORC1 binds the ULK1 complex (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
Active MTORC1 phosphorylates ULK1 (Drosophila melanogaster)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
MTORC1 dissociates from ULK complex (Drosophila melanogaster)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
Rheb in the MTORC1 complex hydrolyses GTP (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Drosophila melanogaster)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular response to starvation (Drosophila melanogaster)
Amino acids regulate mTORC1 (Drosophila melanogaster)
RRAGA,B hydrolyzes GTP (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
mTORC1 binds RHEB:GTP (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
TP53 Regulates Metabolic Genes (Drosophila melanogaster)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
PTEN Regulation (Drosophila melanogaster)
Regulation of PTEN gene transcription (Drosophila melanogaster)
MAF1 translocates to the nucleus (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
mTORC1 phosphorylates MAF1 (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
MTOR signalling (Drosophila melanogaster)
AKT1S1 (PRAS40) binds mTORC1 (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Drosophila melanogaster)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
Energy dependent regulation of mTOR by LKB1-AMPK (Drosophila melanogaster)
AMPK phosphorylates Raptor in the mTORC1 complex (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
Formation of active mTORC1 complex (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
GTP loading by Rheb (Drosophila melanogaster)
RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
mTORC1 phosphorylates AKT1S1 (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
mTORC1-mediated signalling (Drosophila melanogaster)
Phosphorylation of 4E-BP1 by activated mTORC1 (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
RHEB [lysosomal membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VND8 Rheb
Gene Names
Rheb, CG1081
Chain
chain:1-179, propeptide:180-182
Reference Genes
BioGPS Gene:117332 Rheb
KEGG Gene (Drosophila melanogaster):Dmel_CG1081 Rheb
Monarch:117332 Rheb
NCBI Gene:117332 Rheb
Reference Transcript
RefSeq:NM_169069.3 Rheb
RefSeq:NM_169068.3 Rheb
Other Identifiers
117332
152298_at
1630949_s_at
GO:0000082
GO:0000139
GO:0000166
GO:0000278
GO:0002052
GO:0003824
GO:0003924
GO:0005515
GO:0005525
GO:0005737
GO:0005783
GO:0005789
GO:0005794
GO:0005829
GO:0005886
GO:0006914
GO:0007165
GO:0007264
GO:0007430
GO:0008286
GO:0010506
GO:0010507
GO:0010942
GO:0012505
GO:0016020
GO:0016787
GO:0019003
GO:0023052
GO:0030154
GO:0030307
GO:0033500
GO:0034330
GO:0035264
GO:0042254
GO:0042594
GO:0042632
GO:0043226
GO:0045176
GO:0045727
GO:0045793
GO:0045887
GO:0046872
GO:0048856
GO:0055088
GO:0090070
GO:1902669
GO:1903940
GO:1904263
GO:1904503
GO:2000377
Participates
as a component of
RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
Other forms of this molecule
RHEB [plasma membrane]
RHEB [endosome membrane]
Inferred From
RHEB [lysosomal membrane]
(Homo sapiens)
Cross References
RefSeq
NP_730951.2
,
NP_730950.2
Flybase
FBgn0041191
PRO
Q9VND8
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