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Active mTORC1 complex [lysosomal membrane]
Stable Identifier
R-DME-165678
Type
Complex
Species
Drosophila melanogaster
Compartment
lysosomal membrane
Locations in the PathwayBrowser
Expand all
Autophagy (Drosophila melanogaster)
Macroautophagy (Drosophila melanogaster)
Active MTORC1 binds the ULK1 complex (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
Active MTORC1 phosphorylates ULK1 (Drosophila melanogaster)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
Rheb in the MTORC1 complex hydrolyses GTP (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Drosophila melanogaster)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
TP53 Regulates Metabolic Genes (Drosophila melanogaster)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
PTEN Regulation (Drosophila melanogaster)
Regulation of PTEN gene transcription (Drosophila melanogaster)
MAF1 translocates to the nucleus (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1 phosphorylates MAF1 (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
MTOR signalling (Drosophila melanogaster)
AKT1S1 (PRAS40) binds mTORC1 (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Drosophila melanogaster)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
Energy dependent regulation of mTOR by LKB1-AMPK (Drosophila melanogaster)
AMPK phosphorylates Raptor in the mTORC1 complex (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
Formation of active mTORC1 complex (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1 phosphorylates AKT1S1 (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1-mediated signalling (Drosophila melanogaster)
Phosphorylation of 4E-BP1 by activated mTORC1 (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane]
(Drosophila melanogaster)
RHEB:GTP [lysosomal membrane]
(Drosophila melanogaster)
Participates
as an input of
AKT1S1 (PRAS40) binds mTORC1 (Drosophila melanogaster)
AMPK phosphorylates Raptor in the mTORC1 complex (Drosophila melanogaster)
Rheb in the MTORC1 complex hydrolyses GTP (Drosophila melanogaster)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Drosophila melanogaster)
Active MTORC1 binds the ULK1 complex (Drosophila melanogaster)
as a component of
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
as an output of
Formation of active mTORC1 complex (Drosophila melanogaster)
This entity regulates
Negatively
MAF1 translocates to the nucleus
(Drosophila melanogaster)
Inferred From
Active mTORC1 complex [lysosomal membrane]
(Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane]
(Homo sapiens)
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