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lic [cytosol]
Stable Identifier
R-DME-168051
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
MAP2K3, O62602
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular Senescence (Drosophila melanogaster)
Oxidative Stress Induced Senescence (Drosophila melanogaster)
MAP3K5 phosphorylates MKK3 and MKK6 (Drosophila melanogaster)
lic [cytosol] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Cytokine Signaling in Immune system (Drosophila melanogaster)
Signaling by Interleukins (Drosophila melanogaster)
Interleukin-17 signaling (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
lic [cytosol] (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Toll-like Receptor Cascades (Drosophila melanogaster)
Toll Like Receptor 10 (TLR10) Cascade (Drosophila melanogaster)
MyD88 cascade initiated on plasma membrane (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
lic [cytosol] (Drosophila melanogaster)
Toll Like Receptor 2 (TLR2) Cascade (Drosophila melanogaster)
Toll Like Receptor TLR1:TLR2 Cascade (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
lic [cytosol] (Drosophila melanogaster)
Toll Like Receptor TLR6:TLR2 Cascade (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
lic [cytosol] (Drosophila melanogaster)
Toll Like Receptor 3 (TLR3) Cascade (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
lic [cytosol] (Drosophila melanogaster)
Toll Like Receptor 4 (TLR4) Cascade (Drosophila melanogaster)
MyD88-independent TLR4 cascade (Drosophila melanogaster)
TRIF (TICAM1)-mediated TLR4 signaling (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
lic [cytosol] (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
lic [cytosol] (Drosophila melanogaster)
Toll Like Receptor 5 (TLR5) Cascade (Drosophila melanogaster)
MyD88 cascade initiated on plasma membrane (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
lic [cytosol] (Drosophila melanogaster)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Drosophila melanogaster)
MyD88 dependent cascade initiated on endosome (Drosophila melanogaster)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
lic [cytosol] (Drosophila melanogaster)
Toll Like Receptor 9 (TLR9) Cascade (Drosophila melanogaster)
MyD88 dependent cascade initiated on endosome (Drosophila melanogaster)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
lic [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:O62602
Gene Names
lic
Reference Genes
BioGPS Gene:32257 lic
CTD Gene:32257 lic
ENSEMBL:FBgn0261524
Flybase:FBgn0261524
KEGG Gene (Drosophila melanogaster):Dmel_CG12244 lic
Monarch:32257 lic
NCBI Gene:32257 lic
UCSC:O62602 lic
Reference Transcript
RefSeq:NM_057814.4 lic
Other Identifiers
141616_at
1633665_at
32257
GO:0000165
GO:0001934
GO:0002376
GO:0002385
GO:0003824
GO:0004672
GO:0004708
GO:0005524
GO:0005737
GO:0006468
GO:0007254
GO:0007309
GO:0007314
GO:0010942
GO:0012501
GO:0016301
GO:0016310
GO:0016740
GO:0022414
GO:0023052
GO:0030154
GO:0031435
GO:0033209
GO:0035313
GO:0035331
GO:0036211
GO:0038066
GO:0040018
GO:0042060
GO:0043068
GO:0045793
GO:0048010
GO:0048082
GO:0048856
GO:0048870
GO:0051403
GO:0090090
GO:0140096
Participates
as an input of
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
MAP3K5 phosphorylates MKK3 and MKK6 (Drosophila melanogaster)
Other forms of this molecule
lic [cytosol]
phospho-lic [cytosol]
phospho-lic [cytosol]
phospho-lic [nucleoplasm]
phospho-lic [nucleoplasm]
Inferred From
MAP2K3,MAP2K6 [cytosol]
(Homo sapiens)
MAP2K3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_477162.1
Flybase
FBgn0261524
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8T3Y0
1
SIAH2 [cytosol]
(R-DME-374566-2)
0.488
2
UniProt:P21461
2
SIAH2 [cytosol]
(R-DME-374566)
SIAH1 [cytosol]
(R-DME-374563)
0.488
2
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