Reactome | CDK1 [cytosol]

CDK1 [cytosol]

Stable Identifier

R-DME-170075

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

P23572

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Drosophila melanogaster)

- RNA Polymerase II Transcription (Drosophila melanogaster)
  - Generic Transcription Pathway (Drosophila melanogaster)
    - Transcriptional Regulation by TP53 (Drosophila melanogaster)
      - TP53 Regulates Transcription of Cell Cycle Genes (Drosophila melanogaster)
        
        TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest (Drosophila melanogaster)
        
        SFN dimer binds CDK1 and CCNB1 (Drosophila melanogaster)
        
        CCNB:CDK1 [cytosol] (Drosophila melanogaster)
        
        CDK1 [cytosol] (Drosophila melanogaster)
        
        SFN Dimer:CCNB1:CDK1 [cytosol] (Drosophila melanogaster)
        
        CCNB:CDK1 [cytosol] (Drosophila melanogaster)
        
        CDK1 [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:P23572

Reference Genes

BioGPS Gene:34411

ENSEMBL:FBgn0004106

FlyBase:FBgn0004106

KEGG Gene (Drosophila melanogaster):Dmel_CG5363

Monarch:34411

NCBI Gene:34411

Reference Transcript

RefSeq:NM_057449.4

Other Identifiers

154844_at

1631861_at

34411

GO:0000082

GO:0000086

GO:0000166

GO:0000278

GO:0001700

GO:0003824

GO:0004672

GO:0004674

GO:0004693

GO:0005515

GO:0005524

GO:0005634

GO:0006260

GO:0006351

GO:0006355

GO:0006357

GO:0006468

GO:0007049

GO:0007095

GO:0007140

GO:0007284

GO:0008353

GO:0016301

GO:0016310

GO:0016740

GO:0022414

GO:0023052

GO:0030154

GO:0030174

GO:0030707

GO:0032880

GO:0036211

GO:0043226

GO:0044818

GO:0045169

GO:0048142

GO:0048856

GO:0051301

GO:0055059

GO:0106310

GO:0140013

GO:0140096

GO:1901990

Participates

as an input of

as a component of

Other forms of this molecule

phospho-p-Y4-CDK1 [cytosol]

phospho-p-T14,T161-CDK1 [nucleoplasm]

phospho-p-T14-CDK1 [nucleoplasm]

phospho-p-T14-CDK1 [cytosol]

phospho-p-T14,Y15,T161-CDK1 [cytosol]

phospho-p-T161-CDK1 [cytosol]

phospho-p-T14,Y15,T161-CDK1 [nucleoplasm]

phospho-p-T161-CDK1 [nucleoplasm]

Inferred From

CDK1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_476797.1

Flybase

FBgn0004106

IntEnz

2.7.11.23

PRO

P23572

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P54733	4	CycE [cytosol] (R-DME-157452) CycE [cytosol] (R-DME-157443) CycE [nucleoplasm] (R-DME-68367) CycE [nucleoplasm] (R-DME-68363)	0.785	6
UniProt:Q9VHN1 Q9VHN1			0.712	5
UniProt:P14785	6	CycA [nucleoplasm] (R-DME-6783099) CycA [nucleoplasm] (R-DME-6783068) CycA [cytosol] (R-DME-157444) CycA [cytosol] (R-DME-157446) CycA [nucleoplasm] (R-DME-68891) CycA [nucleoplasm] (R-DME-68905)	0.657	3
UniProt:Q9I7I0 CCNB3			0.623	3
UniProt:Q03019	14	twe [cytosol] (R-DME-6782810-2) phospho-twe [cytosol] (R-DME-69588-2) phospho-twe [nucleoplasm] (R-DME-6802968-2) phospho-twe [nucleoplasm] (R-DME-143488-2) phospho-twe [cytosol] (R-DME-75003-2) phospho-twe [nucleoplasm] (R-DME-156496-2) twe [cytosol] (R-DME-157410-2) twe [nucleoplasm] (R-DME-69741-2) twe [cytosol] (R-DME-157879-2) phospho-twe [cytosol] (R-DME-8981697-2) twe [cytosol] (R-DME-157412-2) phospho-twe [nucleoplasm] (R-DME-156668-2) twe [nucleoplasm] (R-DME-143487-2) twe [nucleoplasm] (R-DME-69734-2)	0.621	4
UniProt:P25008	1	CycC [nucleoplasm] (R-DME-212418)	0.621	4
UniProt:Q961D1	1	CycK [nucleoplasm] (R-DME-6796619)	0.621	4
UniProt:Q24152	1	Cks30A [nucleoplasm] (R-DME-187533)	0.547	2
UniProt:P20439	5	CycB [cytosol] (R-DME-68897) CycB [cytosol] (R-DME-157451) phospho-CycB [nucleoplasm] (R-DME-170049) phospho-CycB [cytosol] (R-DME-170058) CycB [nucleoplasm] (R-DME-68901)	0.527	2

Cite Us!