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put [plasma membrane]
Stable Identifier
R-DME-170842
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
plasma membrane
Synonyms
TGFBR2, A0A0B4KG59
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Signaling by TGFB family members (Drosophila melanogaster)
Signaling by TGF-beta Receptor Complex (Drosophila melanogaster)
TGF-beta receptor signaling activates SMADs (Drosophila melanogaster)
Activated type I receptor phosphorylates SMAD2/3 directly (Drosophila melanogaster)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
CBL binds TGFBR2 (Drosophila melanogaster)
TGFBR2:CBL [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
CBL neddylates TGFBR2 (Drosophila melanogaster)
TGFBR2:CBL [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
Dimeric TGF-beta-1 binds to the receptor (Drosophila melanogaster)
Dimeric TGFB1:TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
Downregulation of TGF-beta receptor signaling (Drosophila melanogaster)
Degradation of TGF-beta receptor complex (Drosophila melanogaster)
TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7 [plasma membrane] (Drosophila melanogaster)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Drosophila melanogaster)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Drosophila melanogaster)
TGFB1: p-TGFBR: STRAP: SMAD7 [plasma membrane] (Drosophila melanogaster)
TGFB1:p-TGFBR:STRAP [plasma membrane] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
TGFB1:p-TGFBR:STRAP [plasma membrane] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
Phosphorylated SMAD2/3 dissociates from TGFBR (Drosophila melanogaster)
TGFB1:p-TGFBR:ZFYVE9 [early endosome membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
TGFBR2 phosphorylates TGFBR1 (Drosophila melanogaster)
TGFB1:TGFBR2:TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
TGFBR2 recruits TGFBR1 (Drosophila melanogaster)
Dimeric TGFB1:TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
TGFB1:TGFBR2:TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) (Drosophila melanogaster)
Disassembly of tight junctions (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
SMURF1 binds phosphorylated PARD6A (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
SMURF1 ubiquitinates RHOA (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
put [plasma membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:A0A0B4KG59
Gene Names
put
Reference Genes
BioGPS Gene:41772 put
ENSEMBL:FBgn0003169
Flybase:FBgn0003169
Monarch:41772 put
NCBI Gene:41772 put
Reference Transcript
RefSeq:NM_001275646.1 put
Other Identifiers
154591_at
1631769_at
41772
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0004675
GO:0005024
GO:0005524
GO:0005886
GO:0005975
GO:0006091
GO:0006468
GO:0007178
GO:0007391
GO:0007411
GO:0007424
GO:0007428
GO:0007443
GO:0007476
GO:0008258
GO:0009953
GO:0016020
GO:0016301
GO:0016310
GO:0016323
GO:0016362
GO:0016740
GO:0017002
GO:0022414
GO:0023052
GO:0030154
GO:0030509
GO:0030718
GO:0032924
GO:0034330
GO:0035222
GO:0036122
GO:0036211
GO:0042078
GO:0042593
GO:0043235
GO:0045464
GO:0045705
GO:0045819
GO:0046872
GO:0048179
GO:0048185
GO:0048666
GO:0048856
GO:0060089
GO:0060391
GO:0070724
GO:0071333
GO:0071363
GO:0098821
GO:0140096
GO:1904398
Participates
as an input of
CBL binds TGFBR2 (Drosophila melanogaster)
Dimeric TGF-beta-1 binds to the receptor (Drosophila melanogaster)
as a component of
TGFBR2:CBL [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
Other forms of this molecule
put [plasma membrane]
put [plasma membrane]
put [plasma membrane]
Inferred From
TGFBR2 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_001262575.1
Flybase
FBgn0003169
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