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fzr [cytosol]
Stable Identifier
R-DME-174249
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
FZR1, Q9W4H9
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
Regulation of mitotic cell cycle (Drosophila melanogaster)
APC/C-mediated degradation of cell cycle proteins (Drosophila melanogaster)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Drosophila melanogaster)
Association of cell cycle proteins with the APC/C:Cdh1 complex (Drosophila melanogaster)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
Degradation of multiubiquitinated cell cycle proteins (Drosophila melanogaster)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Drosophila melanogaster)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Drosophila melanogaster)
Association of Cdh1 with the APC/C (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
Dephosphorylation of phospho-Cdh1 (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
Regulation of APC/C activators between G1/S and early anaphase (Drosophila melanogaster)
SCF-beta-TrCP mediated degradation of Emi1 (Drosophila melanogaster)
Ubiquitination of Emi1 by SCF-beta-TrCP (Drosophila melanogaster)
SCF-associated multiubiquitinated Emi1complexes [cytosol] (Drosophila melanogaster)
SCF-beta-TrCP:phospho-Emi1 complexes [cytosol] (Drosophila melanogaster)
phospho-Emi1:Cdc20/Cdh1 complexes [cytosol] (Drosophila melanogaster)
phospho-Emi1(Ser 145, Ser 149):Cdc20/Cdh1 complexes [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
phospho-Emi1(Ser 182):Cdc20/Cdh1:complexes [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
SCF-beta-TrCP:phospho-Emi1 complexes [cytosol] (Drosophila melanogaster)
phospho-Emi1:Cdc20/Cdh1 complexes [cytosol] (Drosophila melanogaster)
phospho-Emi1(Ser 145, Ser 149):Cdc20/Cdh1 complexes [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
phospho-Emi1(Ser 182):Cdc20/Cdh1:complexes [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
S Phase (Drosophila melanogaster)
Synthesis of DNA (Drosophila melanogaster)
Switching of origins to a post-replicative state (Drosophila melanogaster)
CDK-mediated phosphorylation and removal of Cdc6 (Drosophila melanogaster)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
DNA Replication (Drosophila melanogaster)
Synthesis of DNA (Drosophila melanogaster)
Switching of origins to a post-replicative state (Drosophila melanogaster)
CDK-mediated phosphorylation and removal of Cdc6 (Drosophila melanogaster)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Class I MHC mediated antigen processing & presentation (Drosophila melanogaster)
Antigen processing: Ubiquitination & Proteasome degradation (Drosophila melanogaster)
Interaction of E3 with substrate and E2-Ub complex (Drosophila melanogaster)
Ag-substrate:E3:E2:Ub [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
Polyubiquitination of substrate (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
E3:K48-polyubiquitinated substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
E3:Ub:substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
Release of E3 from polyubiquitinated substrate (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
E3:K48-polyubiquitinated substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
Transfer of Ub from E2 to substrate and release of E2 (Drosophila melanogaster)
Ag-substrate:E3:E2:Ub [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
E3:Ub:substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
APC/C E3 ligase complex [cytosol] (Drosophila melanogaster)
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
fzr [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9W4H9
Gene Names
fzr
Reference Genes
BioGPS Gene:45922 fzr
CTD Gene:45922 fzr
ENSEMBL:FBgn0262699
Flybase:FBgn0262699
KEGG Gene (Drosophila melanogaster):Dmel_CG3000 fzr
Monarch:45922 fzr
NCBI Gene:45922 fzr
UCSC:Q9W4H9 fzr
Reference Transcript
RefSeq:NM_080113.3 fzr
RefSeq:NM_167013.2 fzr
Other Identifiers
142823_at
1629844_s_at
45922
GO:0000278
GO:0001745
GO:0005515
GO:0005634
GO:0005680
GO:0005737
GO:0005813
GO:0005814
GO:0005815
GO:0005819
GO:0005856
GO:0007088
GO:0007455
GO:0008347
GO:0010001
GO:0010997
GO:0030154
GO:0030163
GO:0030424
GO:0031145
GO:0031536
GO:0036211
GO:0043226
GO:0048856
GO:0048870
GO:0097027
GO:0098772
GO:0140014
GO:1904668
GO:1905786
GO:1990757
Participates
as an output of
Dephosphorylation of phospho-Cdh1 (Drosophila melanogaster)
as an input of
Association of Cdh1 with the APC/C (Drosophila melanogaster)
as a component of
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
as a member of
Cdc20/Cdh1 [cytosol] (Drosophila melanogaster)
Other forms of this molecule
phospho-fzr [cytosol]
phospho-fzr [nucleoplasm]
fzr [nucleoplasm]
Inferred From
FZR1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_726941.1
,
NP_524852.2
Flybase
FBgn0262699
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