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CDC42:GTP [plasma membrane]
Stable Identifier
R-DME-182921
Type
Complex
Species
Drosophila melanogaster
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Developmental Biology (Drosophila melanogaster)
Myogenesis (Drosophila melanogaster)
Nuclear translocation of p38 MAPK (Drosophila melanogaster)
ABL1:JLP:CDO complex [plasma membrane] (Drosophila melanogaster)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Drosophila melanogaster)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
pp38 alpha/beta/gamma:ABL1:JLP:CDO complex [plasma membrane] (Drosophila melanogaster)
ABL1:JLP:CDO complex [plasma membrane] (Drosophila melanogaster)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Drosophila melanogaster)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
EPH-Ephrin signaling (Drosophila melanogaster)
EPHB-mediated forward signaling (Drosophila melanogaster)
CDC42 and PIP2 bind WASL, activating it (Drosophila melanogaster)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Drosophila melanogaster)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
N-WASP binds ARP2/3 and G-actin (Drosophila melanogaster)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Drosophila melanogaster)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] (Drosophila melanogaster)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Drosophila melanogaster)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
Netrin-1 signaling (Drosophila melanogaster)
DCC mediated attractive signaling (Drosophila melanogaster)
Activation of Cdc42 (Drosophila melanogaster)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Costimulation by the CD28 family (Drosophila melanogaster)
CD28 co-stimulation (Drosophila melanogaster)
CD28 dependent Vav1 pathway (Drosophila melanogaster)
Activation of PAKs by RAC1 and CDC42 (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Fcgamma receptor (FCGR) dependent phagocytosis (Drosophila melanogaster)
Regulation of actin dynamics for phagocytic cup formation (Drosophila melanogaster)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Drosophila melanogaster)
Mother filament:branching complex [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
Autophosphorylation of PAK1 (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
Detachment of WASP/WAVE (Drosophila melanogaster)
Mother filament:branching complex [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
WAVE2, WASP, N-WASP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
RAC1 and CDC42 activate PAK1 (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK6/MAPK4 signaling (Drosophila melanogaster)
Activation of PAKs by RAC1 and CDC42 (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
Autophosphorylation of PAK1,2,3 (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Drosophila melanogaster)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G-protein beta:gamma signalling (Drosophila melanogaster)
G beta:gamma signalling through CDC42 (Drosophila melanogaster)
Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated (Drosophila melanogaster)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated (Drosophila melanogaster)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by EGFR (Drosophila melanogaster)
EGFR downregulation (Drosophila melanogaster)
Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 (Drosophila melanogaster)
Beta-Pix:CDC42:GTP [cytosol] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Drosophila melanogaster)
Beta-Pix:CDC42:GTP [cytosol] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Drosophila melanogaster)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
Beta-Pix:CDC42:GTP [cytosol] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
Ub-Beta-Pix:CDC42:GTP [cytosol] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP binds CBL:Beta-Pix (Drosophila melanogaster)
Beta-Pix:CDC42:GTP [cytosol] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CBL:Beta-Pix:CDC42:GTP [cytosol] (Drosophila melanogaster)
Beta-Pix:CDC42:GTP [cytosol] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Drosophila melanogaster)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
Beta-Pix:CDC42:GTP [cytosol] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Drosophila melanogaster)
Beta-Pix:CDC42:GTP [cytosol] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
CDC42:GTP binds PAK2 (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
PAK2 dimer:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
FYN phosphorylates PAK2 (Drosophila melanogaster)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
p-2Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
p-3Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
PAK2 autophorylates (Drosophila melanogaster)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
PAK2 dimer:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
p-2Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
p38 MAPK activation by VEGFR (Drosophila melanogaster)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
p-3Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase Effectors (Drosophila melanogaster)
RHO GTPases Activate Formins (Drosophila melanogaster)
FMNL2 binds CDC42:GTP (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP:FMNL2 [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
RHO GTPases Activate WASPs and WAVEs (Drosophila melanogaster)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Drosophila melanogaster)
Mother filament:branching complex [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
Detachment of WASP/WAVE (Drosophila melanogaster)
Mother filament:branching complex [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
WAVE2, WASP, N-WASP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
RHO GTPases activate PAKs (Drosophila melanogaster)
Autophosphorylation of PAK1,2,3 (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Drosophila melanogaster)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
RAC1 and CDC42 activate PAK1 (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
RAC1 and CDC42 activate PAK2 (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
RAC1 and CDC42 activate PAK3 (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Drosophila melanogaster)
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
RHO GTPase cycle (Drosophila melanogaster)
CDC42 GTPase cycle (Drosophila melanogaster)
CDC42 GAPs stimulate CDC42 GTPase activity (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42 GEFs activate CDC42 (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42 translocates to the endoplasmic reticulum membrane (Drosophila melanogaster)
CDC42:GTP [plasma membrane] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
CDC42 [plasma membrane]
(Drosophila melanogaster)
GTP [cytosol]
Participates
as an input of
CDC42 translocates to the endoplasmic reticulum membrane (Drosophila melanogaster)
CDC42 GAPs stimulate CDC42 GTPase activity (Drosophila melanogaster)
CDC42:GTP binds PAK2 (Drosophila melanogaster)
FMNL2 binds CDC42:GTP (Drosophila melanogaster)
as an output of
CDC42 GEFs activate CDC42 (Drosophila melanogaster)
Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex (Drosophila melanogaster)
as a component of
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Drosophila melanogaster)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Drosophila melanogaster)
p-3Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
p-2Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
PAK2 dimer:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
Ub-Beta-Pix:CDC42:GTP [cytosol] (Drosophila melanogaster)
Beta-Pix:CDC42:GTP [cytosol] (Drosophila melanogaster)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Drosophila melanogaster)
CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Drosophila melanogaster)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
CDC42:GTP:FMNL2 [plasma membrane] (Drosophila melanogaster)
as a member of
CDC42:GTP, RAC1:GTP [plasma membrane] (Drosophila melanogaster)
Inferred From
CDC42:GTP [plasma membrane]
(Homo sapiens)
CDC42:GTP [plasma membrane]
(Homo sapiens)
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