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About
What is Reactome ?
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Team
Scientific Advisory Board
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
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EndoA [cytosol]
Stable Identifier
R-DME-182958
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
SH3GL2, Q8T390
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by EGFR (Drosophila melanogaster)
EGFR downregulation (Drosophila melanogaster)
Assembly of EGFR complex in clathrin-coated vesicles (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
CBL-mediated ubiquitination of CIN85 (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:Ub-CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Drosophila melanogaster)
Ub-CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
EGFR binds EPS15, EPN1, EPS15L1 (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:EPS15:HGS:STAM [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
EGFR phosphorylates EPS15 (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:EPS15:HGS:STAM [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
PTPN3 dephosphorylates EPS15 (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:EPS15:HGS:STAM [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
Sprouty sequesters CBL away from active EGFR (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:SPRY1/2:Endophilin:Epsin:Eps15L1:EPS15 [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
Vesicle-mediated transport (Drosophila melanogaster)
Membrane Trafficking (Drosophila melanogaster)
Clathrin-mediated endocytosis (Drosophila melanogaster)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
BAR domain proteins recruit dynamin (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
Cargo recognition for clathrin-mediated endocytosis (Drosophila melanogaster)
Epsin family proteins bind ubiquitinated cargo (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
Clathrin recruits PIK3C2A (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
Endophilins recruit synaptojanins to the clathrin-coated pit (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
F- and N- BAR domain proteins bind the clathrin-coated pit (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
SNX9 recruits components of the actin polymerizing machinery (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
trans-Golgi Network Vesicle Budding (Drosophila melanogaster)
Golgi Associated Vesicle Biogenesis (Drosophila melanogaster)
trans-Golgi Network Coat Assembly (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
trans-Golgi Network Vesicle Scission (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
Lysosome Vesicle Biogenesis (Drosophila melanogaster)
trans-Golgi Network Lysosomal Vesicle Scission (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Drosophila melanogaster)
EndoA [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q8T390
Gene Names
EndoA
Reference Genes
BioGPS Gene:42265 EndoA
CTD Gene:42265 EndoA
ENSEMBL:FBgn0038659
Flybase:FBgn0038659
KEGG Gene (Drosophila melanogaster):Dmel_CG14296 EndoA
Monarch:42265 EndoA
NCBI Gene:42265 EndoA
Reference Transcript
RefSeq:NM_138767.3 EndoA
RefSeq:NM_169838.2 EndoA
RefSeq:NM_001275788.1 EndoA
Other Identifiers
152475_at
1634452_s_at
42265
GO:0000045
GO:0005515
GO:0005543
GO:0005622
GO:0005737
GO:0005829
GO:0006897
GO:0006914
GO:0008289
GO:0009267
GO:0016020
GO:0016191
GO:0016192
GO:0016740
GO:0042171
GO:0048488
GO:0050803
GO:0061024
GO:0061174
GO:0097320
GO:0097749
GO:0097753
GO:0098793
GO:0098978
GO:0150007
Participates
as an output of
trans-Golgi Network Vesicle Scission (Drosophila melanogaster)
trans-Golgi Network Lysosomal Vesicle Scission (Drosophila melanogaster)
as an input of
trans-Golgi Network Coat Assembly (Drosophila melanogaster)
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Drosophila melanogaster)
as a component of
SH3GL2 dimer [cytosol] (Drosophila melanogaster)
Other forms of this molecule
EndoA [Golgi membrane]
EndoA [plasma membrane]
EndoA [cytosol]
EndoA [cytosol]
Inferred From
SH3GL2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_620122.2
,
NP_732383.1
,
NP_001262717.1
Flybase
FBgn0038659
PRO
Q8T390
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9VE96
4
l(3)05822 [endocytic vesicle membrane]
(R-DME-535014-2)
l(3)05822 [plasma membrane]
(R-DME-202134-2)
l(3)05822 [cytosol]
(R-DME-182926-2)
l(3)05822 [cytosol]
(R-DME-182957-2)
0.621
3
UniProt:Q9W3S4 Q9W3S4
0.488
2
UniProt:Q8T390
5
EndoA [Golgi membrane]
(R-DME-351189)
EndoA [plasma membrane]
(R-DME-177495)
EndoA [cytosol]
(R-DME-182958)
EndoA [cytosol]
(R-DME-8867734)
EndoA [cytosol]
(R-DME-8867732)
0.488
2
UniProt:Q4V5L1 Q4V5L1
0.488
2
UniProt:P21461
2
SIAH2 [cytosol]
(R-DME-374566)
SIAH1 [cytosol]
(R-DME-374563)
0.488
2
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