Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Pvf1 [extracellular region]
Stable Identifier
R-DME-184199
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
extracellular region
Synonyms
PDGFA-1, Q9VWP6
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Drosophila melanogaster)
Non-integrin membrane-ECM interactions (Drosophila melanogaster)
HSPG2 binds FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer (Drosophila melanogaster)
FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
HSPG2:FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer [extracellular region] (Drosophila melanogaster)
FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
Hemostasis (Drosophila melanogaster)
Platelet activation, signaling and aggregation (Drosophila melanogaster)
Response to elevated platelet cytosolic Ca2+ (Drosophila melanogaster)
Platelet degranulation (Drosophila melanogaster)
Exocytosis of platelet alpha granule contents (Drosophila melanogaster)
Platelet alpha granule contents [extracellular region] (Drosophila melanogaster)
PDGF dimer [extracellular region] (Drosophila melanogaster)
PDGF AB heterodimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
Negative regulation of the PI3K/AKT network (Drosophila melanogaster)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Drosophila melanogaster)
PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activator:PI3K [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activator:PI3K [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
RAS GEFs promote RAS nucleotide exchange (Drosophila melanogaster)
RAS GEFs [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by PDGF (Drosophila melanogaster)
Autophosphorylation of PDGF alpha receptors (Drosophila melanogaster)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PDGFR:type I PDGFR-binding TKIs [plasma membrane] (Drosophila melanogaster)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
Phospho PDGF alpha receptor:PDGF dimers [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
Downstream signal transduction (Drosophila melanogaster)
Activated PLC gamma dissociates from the PDGF receptor (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
Activation of Src (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:MyrG-p-Y419-SRC [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
Crk binds to the active PDGF receptor (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
GRB2:SOS1 complex binds to the active receptor (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
Nck binds to the active PDGF receptor (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PDGF:Phospho-PDGFR receptor dimer:Nck [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PI3-kinase binds to the active receptor (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PLC-gamma binds to the active receptor (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
Phosphorylation of PLCgamma by PDGFR (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
SH2 domain of Src binds to the active receptor (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
STAT binds to the active receptor (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
p130Cas and C3G bind PDGFR bound Crk (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PDGF dimer binds two receptors simultaneously (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PDGF:PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PDGF-AA clevage by Furin (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PDGFRs bind type I TKI (Drosophila melanogaster)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
PDGFR:type I PDGFR-binding TKIs [plasma membrane] (Drosophila melanogaster)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Pvf1 [extracellular region] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VWP6
Gene Names
Pvf1
Reference Genes
BioGPS Gene:32876 Pvf1
CTD Gene:32876 Pvf1
ENSEMBL:FBgn0030964
FlyBase:FBgn0030964
Monarch:32876 Pvf1
NCBI Gene:32876 Pvf1
UCSC:Q9VWP6 Pvf1
Reference Transcript
RefSeq:NM_078683.3 Pvf1
Other Identifiers
145330_at
1631638_at
32876
GO:0005172
GO:0005576
GO:0005615
GO:0007298
GO:0007391
GO:0007435
GO:0007443
GO:0008083
GO:0008201
GO:0008284
GO:0008347
GO:0012501
GO:0016020
GO:0022414
GO:0023052
GO:0030031
GO:0030154
GO:0030335
GO:0031954
GO:0035099
GO:0035313
GO:0036211
GO:0042060
GO:0044319
GO:0046330
GO:0048010
GO:0048018
GO:0048856
GO:0048870
GO:0060548
GO:0061327
GO:0070851
GO:0098772
GO:1903688
GO:2000683
GO:2001234
Participates
as a component of
PDGF AB heterodimer [extracellular region] (Drosophila melanogaster)
active PDGF-AA dimer [extracellular region] (Drosophila melanogaster)
Other forms of this molecule
Pvf1 [platelet alpha granule lumen]
Pvf1 [platelet alpha granule lumen]
Pvf1 [platelet alpha granule lumen]
Pvf1 [extracellular region]
Pvf1 [extracellular region]
Pvf1 [extracellular region]
Pvf1 [extracellular region]
Pvf1 [extracellular region]
Pvf1 [extracellular region]
Pvf1 [Golgi lumen]
Pvf1 [Golgi lumen]
Pvf1 [Golgi membrane]
Pvf1 [Golgi membrane]
Pvf1 [Golgi membrane]
Pvf1 [endoplasmic reticulum lumen]
Pvf1 [endoplasmic reticulum lumen]
Pvf1 [endoplasmic reticulum lumen]
Pvf1 [endoplasmic reticulum lumen]
Pvf1 [endoplasmic reticulum lumen]
Pvf1 [Golgi lumen]
Pvf1 [Golgi membrane]
Pvf1 [Golgi membrane]
Pvf1 [extracellular region]
Pvf1 [extracellular region]
Pvf1 [extracellular region]
Inferred From
PDGFA [extracellular region]
(Homo sapiens)
Active platelet-derived growth factor A chain isoforms [extracellular region]
(Homo sapiens)
PDGFA-1 [extracellular region]
(Homo sapiens)
Cross References
RefSeq
NP_523407.1
Flybase
FBgn0030964
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
