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active PDGF-BB dimer [extracellular region]
Stable Identifier
R-DME-184206
Type
Complex
Species
Drosophila melanogaster
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Drosophila melanogaster)
Non-integrin membrane-ECM interactions (Drosophila melanogaster)
HSPG2 binds FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer (Drosophila melanogaster)
FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
HSPG2:FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer [extracellular region] (Drosophila melanogaster)
FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
Hemostasis (Drosophila melanogaster)
Platelet activation, signaling and aggregation (Drosophila melanogaster)
Response to elevated platelet cytosolic Ca2+ (Drosophila melanogaster)
Platelet degranulation (Drosophila melanogaster)
Exocytosis of platelet alpha granule contents (Drosophila melanogaster)
Platelet alpha granule contents [extracellular region] (Drosophila melanogaster)
PDGF dimer [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
Negative regulation of the PI3K/AKT network (Drosophila melanogaster)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Drosophila melanogaster)
PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activator:PI3K [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activator:PI3K [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
RAS GEFs promote RAS nucleotide exchange (Drosophila melanogaster)
RAS GEFs [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by PDGF (Drosophila melanogaster)
Autophosphorylation of PDGF alpha receptors (Drosophila melanogaster)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PDGFR:type I PDGFR-binding TKIs [plasma membrane] (Drosophila melanogaster)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
Phospho PDGF alpha receptor:PDGF dimers [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
Autophosphorylation of PDGF alpha/beta receptors (Drosophila melanogaster)
PDGF alpha/beta:PDGF AB and BB dimers [plasma membrane] (Drosophila melanogaster)
PDGF AB or BB homodimers [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
Phospho PDGF alpha-beta dimer:PDGF AB or BB dimers [plasma membrane] (Drosophila melanogaster)
PDGF AB or BB homodimers [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
Autophosphorylation of PDGF beta receptors (Drosophila melanogaster)
PDGF beta receptor:PDGF chain B homodimer [plasma membrane] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
Phospho PDGF beta receptor: PDGF chain B homodimer [plasma membrane] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
Downstream signal transduction (Drosophila melanogaster)
Activated PLC gamma dissociates from the PDGF receptor (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
Activation of Src (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:MyrG-p-Y419-SRC [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
Crk binds to the active PDGF receptor (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
GAP binds to PDGF-beta receptors only (Drosophila melanogaster)
Phospho PDGF beta receptor: PDGF chain B homodimer [plasma membrane] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
Phospho-beta receptor homodimer:GAP [plasma membrane] (Drosophila melanogaster)
Phospho PDGF beta receptor: PDGF chain B homodimer [plasma membrane] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
GRB2:SOS1 complex binds to the active receptor (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
Nck binds to the active PDGF receptor (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PDGF:Phospho-PDGFR receptor dimer:Nck [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PI3-kinase binds to the active receptor (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PLC-gamma binds to the active receptor (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
Phosphorylation of PLCgamma by PDGFR (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
SH2 domain of Src binds to the active receptor (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
STAT binds to the active receptor (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
p130Cas and C3G bind PDGFR bound Crk (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PDGF dimer binds two receptors simultaneously (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PDGF:PDGF receptor dimer [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PDGF-BB clevage by Furin (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PDGFRs bind type I TKI (Drosophila melanogaster)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
PDGFR:type I PDGFR-binding TKIs [plasma membrane] (Drosophila melanogaster)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
active PDGF-BB dimer [extracellular region] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
Pvf1 [extracellular region]
(Drosophila melanogaster)
Participates
as a member of
PDGF dimer [extracellular region] (Drosophila melanogaster)
FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer [extracellular region] (Drosophila melanogaster)
PDGF AB or BB homodimers [extracellular region] (Drosophila melanogaster)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Drosophila melanogaster)
as a component of
Phospho PDGF beta receptor: PDGF chain B homodimer dephosphorylated at Y1021 [plasma membrane] (Drosophila melanogaster)
Phospho PDGF beta receptor: PDGF chain B homodimer [plasma membrane] (Drosophila melanogaster)
PDGF beta receptor:PDGF chain B homodimer [plasma membrane] (Drosophila melanogaster)
as an output of
PDGF-BB clevage by Furin (Drosophila melanogaster)
Inferred From
PDGFB homodimer [extracellular region]
(Homo sapiens)
active PDGF-BB dimer [extracellular region]
(Homo sapiens)
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