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ARRB [cytosol]
Stable Identifier
R-DME-1911410
Type
Set [DefinedSet]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
Beta-arrestin
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (s) signalling events (Drosophila melanogaster)
ADRB2:Catecholamine binds ARRB1, ARRB2 (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
pS-ADRB2:Catecholamine:ARRB1,ARRB2 [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
Vesicle-mediated transport (Drosophila melanogaster)
Membrane Trafficking (Drosophila melanogaster)
Clathrin-mediated endocytosis (Drosophila melanogaster)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
BAR domain proteins recruit dynamin (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
Cargo recognition for clathrin-mediated endocytosis (Drosophila melanogaster)
ARBB recruits GPCRs into clathrin-coated pits (Drosophila melanogaster)
ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
ARRB bind GPCRs (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
Clathrin recruits PIK3C2A (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
Endophilins recruit synaptojanins to the clathrin-coated pit (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
F- and N- BAR domain proteins bind the clathrin-coated pit (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
RAB5 and GAPVD1 bind AP-2 (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
Participants
members
Homologues of ARRB1 [cytosol]
(Drosophila melanogaster)
krz [cytosol]
(Drosophila melanogaster)
Participates
as a component of
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
SMO dimer:ARRB:KIF3A [endocytic vesicle membrane] (Drosophila melanogaster)
pS-ADRB2:Catecholamine:ARRB1,ARRB2 [plasma membrane] (Drosophila melanogaster)
as an input of
ARRB bind GPCRs (Drosophila melanogaster)
ADRB2:Catecholamine binds ARRB1, ARRB2 (Drosophila melanogaster)
Inferred From
ARRB [cytosol]
(Homo sapiens)
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