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SRC-2 [cytosol]
Stable Identifier
R-DME-191648
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
P00528
Locations in the PathwayBrowser for interactor UniProt:Q03720
Expand all
Autophagy (Drosophila melanogaster)
Macroautophagy (Drosophila melanogaster)
Selective autophagy (Drosophila melanogaster)
Mitophagy (Drosophila melanogaster)
Receptor Mediated Mitophagy (Drosophila melanogaster)
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Drosophila melanogaster)
SRC-2 [cytosol] (Drosophila melanogaster)
Hemostasis (Drosophila melanogaster)
Platelet activation, signaling and aggregation (Drosophila melanogaster)
Platelet Aggregation (Plug Formation) (Drosophila melanogaster)
Integrin signaling (Drosophila melanogaster)
Autophosphorylation of SRC (Drosophila melanogaster)
SRC-2 [cytosol] (Drosophila melanogaster)
Signal amplification (Drosophila melanogaster)
ADP signalling through P2Y purinoceptor 1 (Drosophila melanogaster)
Src activation following P2Y purinoceptor activation (Drosophila melanogaster)
SRC-2 [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Integrin signaling (Drosophila melanogaster)
Autophosphorylation of SRC (Drosophila melanogaster)
SRC-2 [cytosol] (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase Effectors (Drosophila melanogaster)
RHO GTPases Activate Formins (Drosophila melanogaster)
RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes (Drosophila melanogaster)
SRC-2 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P00528
Reference Genes
BioGPS Gene:48973
CTD Gene:48973
ENSEMBL:FBgn0262733
Flybase:FBgn0262733
KEGG Gene (Drosophila melanogaster):Dmel_CG7524
Monarch:48973
NCBI Gene:48973
Reference Transcript
RefSeq:NM_080195.4
RefSeq:NM_001202122.1
RefSeq:NM_001014562.3
RefSeq:NM_001014561.2
RefSeq:NM_001259700.2
RefSeq:NM_001014564.3
RefSeq:NM_001014563.3
RefSeq:NM_001259699.2
Other Identifiers
143366_at
1634871_s_at
1641253_at
48973
GO:0000166
GO:0002009
GO:0002376
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005102
GO:0005515
GO:0005524
GO:0005829
GO:0005886
GO:0006468
GO:0007010
GO:0007155
GO:0007169
GO:0007293
GO:0007300
GO:0007301
GO:0007349
GO:0007411
GO:0007424
GO:0007435
GO:0007616
GO:0008064
GO:0008302
GO:0008335
GO:0009887
GO:0016043
GO:0016301
GO:0016310
GO:0016319
GO:0016740
GO:0018108
GO:0022414
GO:0023052
GO:0030036
GO:0030046
GO:0030154
GO:0030708
GO:0030717
GO:0030723
GO:0031234
GO:0034330
GO:0034332
GO:0035332
GO:0036058
GO:0036211
GO:0045087
GO:0045172
GO:0045742
GO:0045743
GO:0045874
GO:0045886
GO:0048167
GO:0048468
GO:0048477
GO:0048513
GO:0048856
GO:0050877
GO:0065008
GO:0090136
GO:0098542
GO:0120176
GO:0140096
Participates
as a component of
F2R:ARRB1:active MAPKs:active SRC-1 [plasma membrane] (Drosophila melanogaster)
F2R:ARRB1:MAPKs:SRC-1 [plasma membrane] (Drosophila melanogaster)
F2R:ARRB2:MAPKs:SRC-1 [plasma membrane] (Drosophila melanogaster)
RHOD:GTP:DIAPH2:SRC-1 [endosome membrane] (Drosophila melanogaster)
as an input of
Src activation following P2Y purinoceptor activation (Drosophila melanogaster)
RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes (Drosophila melanogaster)
as a member of
SRC,FYN [cytosol] (Drosophila melanogaster)
SRC,FYN,YES,LYN [cytosol] (Drosophila melanogaster)
Src family tyrosine kinases (SFKs) [cytosol] (Drosophila melanogaster)
Other forms of this molecule
MyrG2-PalmC3-LYN [lysosomal membrane]
MyrG2-PalmC3-LYN [endocytic vesicle membrane]
phospho-p-HCK [cytosol]
FGR [extracellular region]
FGR [secretory granule lumen]
SRC [cytosol]
phospho-p-Y419-SRC [cytosol]
phospho-p-S21,Y420-FYN [cytosol]
MyrG-SRC [plasma membrane]
phospho-p-Y419-SRC-1 [plasma membrane]
phospho-p-Y394-LCK [plasma membrane]
LYN [plasma membrane]
phospho-p-Y397-LYN [cytosol]
phospho-p-Y397-LYN [plasma membrane]
FYN [cytosol]
LCK [cytosol]
phospho-MyrG-p-Y419-SRC [plasma membrane]
phospho-MyrG-p-Y426-YES1 [plasma membrane]
phospho-MyrG-p-Y420-FYN-1 [plasma membrane]
phospho-MyrG,p-Y530-SRC [plasma membrane]
phospho-p-Y420-FYN [cytosol]
LYN [cytosol]
phospho-p-Y419-SRC [cytosol]
SRC-1 [plasma membrane]
FGR [cytosol]
YES1 [cytosol]
HCK [cytosol]
MyrG2-PalmC3-LYN [plasma membrane]
Inferred From
Activated SRC-1 [cytosol]
(Homo sapiens)
SRC-2 [cytosol]
(Homo sapiens)
SRC-1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001014561.1
,
NP_001014563.1
,
NP_524934.2
,
NP_001014562.1
,
NP_001014564.1
,
NP_001246628.1
,
NP_001189051.1
,
NP_001246629.1
Flybase
FBgn0262733
PRO
P00528
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q03720
1
slo [plasma membrane]
(R-DME-2534368)
0.544
3
UniProt:P11346 Raf
20
Phospho PHL [plasma membrane]
(R-DME-205859)
PHL [cytosol]
(R-DME-205713)
phospho-p-S338,Y340,Y341-RAF1 [cytosol]
(R-DME-5624465)
phospho-p-S338-RAF1 [cytosol]
(R-DME-5624469)
BRAF [cytosol]
(R-DME-167224)
phospho-hyperphosphorylated BRAF [plasma membrane]
(R-DME-5675199)
phospho-hyperphosphorylated RAF1 [plasma membrane]
(R-DME-5675193)
phospho-p-S299,S302,T452,T455,S582 ARAF [cytosol]
(R-DME-5672646)
phospho-p-S446,T599,S602,S729 BRAF [cytosol]
(R-DME-5672676)
phospho-p-S338,Y341,T491,S494,S621 RAF1 [cytosol]
(R-DME-5672664)
phospho-p-S446,S729-BRAF [cytosol]
(R-DME-5672673)
phospho-p-S446,T599,S602,S729 BRAF [plasma membrane]
(R-DME-5672679)
phospho-p-S299,S302,T452,T455,S582 ARAF [plasma membrane]
(R-DME-5672648)
phospho-p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane]
(R-DME-5672665)
phospho-p-S582 ARAF [cytosol]
(R-DME-5672681)
phospho-p-S621-RAF1 [cytosol]
(R-DME-206028)
RAF1 [cytosol]
(R-DME-167205)
phospho-p-S214,S582 ARAF [cytosol]
(R-DME-5672639)
phospho-p-S259,S621-RAF1 [cytosol]
(R-DME-109786)
phospho-p-S365,S446,S729 BRAF [cytosol]
(R-DME-5672667)
0.544
3
UniProt:Q9VLA2 GCM2
0.488
2
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