Reactome | alpha-Cat [plasma membrane]

alpha-Cat [plasma membrane]

Stable Identifier

R-DME-191735-2

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

plasma membrane

Synonyms

CTNNA1, P35220

Locations in the PathwayBrowser

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Signal Transduction (Drosophila melanogaster)

- Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
  - Signaling by VEGF (Drosophila melanogaster)
    - VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
      - VEGFR2 mediated vascular permeability (Drosophila melanogaster)
        
        PAK1-3 phosphorylates VE-cadherin (Drosophila melanogaster)
        
        VE-cadherin-Catenin complex [plasma membrane] (Drosophila melanogaster)
        
        Homologues of CTNNA1 [plasma membrane] (Drosophila melanogaster)
        
        alpha-Cat [plasma membrane] (Drosophila melanogaster)
        
        p-S665-VE-cadherin-Catenin complex [plasma membrane] (Drosophila melanogaster)
        
        Homologues of CTNNA1 [plasma membrane] (Drosophila melanogaster)
        
        alpha-Cat [plasma membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:P35220

Gene Names

alpha-Cat

Reference Genes

BioGPS Gene:40517 alpha-Cat

ENSEMBL:FBgn0010215

FlyBase:FBgn0010215

KEGG:dme:Dmel_CG17947 alpha-Cat

Monarch:40517 alpha-Cat

NCBI Gene:40517 alpha-Cat

UCSC:P35220 alpha-Cat

Reference Transcript

RefSeq:NM_079495.3 alpha-Cat

Other Identifiers

154527_at

1632724_at

40517

GO:0003383

GO:0005198

GO:0005515

GO:0005737

GO:0005856

GO:0005886

GO:0005912

GO:0007155

GO:0008013

GO:0008092

GO:0015629

GO:0016342

GO:0016477

GO:0034330

GO:0034332

GO:0034333

GO:0042802

GO:0043226

GO:0045296

GO:0046664

GO:0048870

GO:0051015

GO:0060323

GO:0070161

GO:0098609

Participates

as a member of

Homologues of CTNNA1 [plasma membrane] (Drosophila melanogaster)

Other forms of this molecule

alpha-Cat [cytosol]

Inferred From

CTNNA1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_524219.1

ENSEMBL

FBtr0070038, FBpp0070037

PRO

P35220

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P18824 arm	20	arm [nucleoplasm] (R-DME-3451168) arm [cytosol] (R-DME-448839) arm [cytosol] (R-DME-202930) arm [cytosol] (R-DME-202950) arm [plasma membrane] (R-DME-9038440) arm [plasma membrane] (R-DME-437260) phospho-arm [cytosol] (R-DME-8942374) phospho-arm [cytosol] (R-DME-8942369) phospho-arm [cytosol] (R-DME-8942367) phospho-arm [cytosol] (R-DME-8942363) phospho-arm [cytosol] (R-DME-3134933) phospho-arm [nucleoplasm] (R-DME-3134926) arm [specific granule lumen] (R-DME-6799534) arm [extracellular region] (R-DME-6806309) arm [ficolin-1-rich granule lumen] (R-DME-6801028) arm [cytosol] (R-DME-201598) Phospho (4 sites) ARM [cytosol] (R-DME-205960) ARM [cytosol] (R-DME-205774) Phospho ARM [cytosol] (R-DME-206159) ARM [nucleoplasm] (R-DME-205878)	0.774	5