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ARY [cytosol]
Stable Identifier
R-DME-192142
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
AKR1C4, D2A6K3
Locations in the PathwayBrowser
Expand all
Drug ADME (Drosophila melanogaster)
Prednisone ADME (Drosophila melanogaster)
AKR1C1 hydrogenates PREDN,PREDL (Drosophila melanogaster)
Homologues of AKR1C4 [cytosol] (Drosophila melanogaster)
ARY [cytosol] (Drosophila melanogaster)
Metabolism (Drosophila melanogaster)
Metabolism of lipids (Drosophila melanogaster)
Fatty acid metabolism (Drosophila melanogaster)
Arachidonic acid metabolism (Drosophila melanogaster)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Drosophila melanogaster)
PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Drosophila melanogaster)
Homologues of AKR1C4 [cytosol] (Drosophila melanogaster)
ARY [cytosol] (Drosophila melanogaster)
PGH2 is reduced to PGF2a by AKR1C3 (Drosophila melanogaster)
Homologues of AKR1C4 [cytosol] (Drosophila melanogaster)
ARY [cytosol] (Drosophila melanogaster)
Metabolism of steroids (Drosophila melanogaster)
Bile acid and bile salt metabolism (Drosophila melanogaster)
Synthesis of bile acids and bile salts (Drosophila melanogaster)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Drosophila melanogaster)
5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Drosophila melanogaster)
Homologues of AKR1C4 [cytosol] (Drosophila melanogaster)
ARY [cytosol] (Drosophila melanogaster)
5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol (Drosophila melanogaster)
Homologues of AKR1C4 [cytosol] (Drosophila melanogaster)
ARY [cytosol] (Drosophila melanogaster)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Drosophila melanogaster)
5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol (Drosophila melanogaster)
Homologues of AKR1C4 [cytosol] (Drosophila melanogaster)
ARY [cytosol] (Drosophila melanogaster)
5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Drosophila melanogaster)
Homologues of AKR1C4 [cytosol] (Drosophila melanogaster)
ARY [cytosol] (Drosophila melanogaster)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Drosophila melanogaster)
5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol (Drosophila melanogaster)
Homologues of AKR1C4 [cytosol] (Drosophila melanogaster)
ARY [cytosol] (Drosophila melanogaster)
5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol (Drosophila melanogaster)
Homologues of AKR1C4 [cytosol] (Drosophila melanogaster)
ARY [cytosol] (Drosophila melanogaster)
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of fat-soluble vitamins (Drosophila melanogaster)
Retinoid metabolism and transport (Drosophila melanogaster)
AKRs reduce RBP2:atRAL to RBP2:atROL (Drosophila melanogaster)
AKRs [cytosol] (Drosophila melanogaster)
Homologues of AKR1C4 [cytosol] (Drosophila melanogaster)
ARY [cytosol] (Drosophila melanogaster)
Sensory Perception (Drosophila melanogaster)
Visual phototransduction (Drosophila melanogaster)
Retinoid metabolism and transport (Drosophila melanogaster)
AKRs reduce RBP2:atRAL to RBP2:atROL (Drosophila melanogaster)
AKRs [cytosol] (Drosophila melanogaster)
Homologues of AKR1C4 [cytosol] (Drosophila melanogaster)
ARY [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
Signaling by Retinoic Acid (Drosophila melanogaster)
RA biosynthesis pathway (Drosophila melanogaster)
AKR1C3 reduces atRAL to atROL (Drosophila melanogaster)
Homologues of AKR1C4 [cytosol] (Drosophila melanogaster)
ARY [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:D2A6K3
Gene Names
ARY
Reference Genes
BioGPS Gene:19988923 ARY
ENSEMBL:FBgn0058064
Flybase:FBgn0058064
Monarch:19988923 ARY
NCBI Gene:19988923 ARY
Reference Transcript
RefSeq:NM_001170373.2 ARY
Other Identifiers
1637935_at
19988923
GO:0003824
GO:0004032
GO:0005829
GO:0008106
GO:0016491
GO:0047718
Participates
as a member of
Homologues of AKR1C4 [cytosol] (Drosophila melanogaster)
Other forms of this molecule
ARY [cytosol]
ARY [cytosol]
ARY [mitochondrial matrix]
ARY [cytosol]
ARY [cytosol]
Inferred From
AKR1C4 [cytosol]
(Homo sapiens)
AKR1C1 [cytosol]
(Homo sapiens)
AKR1C2 [cytosol]
(Homo sapiens)
AKR1C3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001163844.1
Flybase
FBgn0058064
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