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CSNK1A1 [cytosol]
Stable Identifier
R-DME-195263
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
P54367
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Signaling by Hedgehog (Drosophila melanogaster)
Hedgehog 'off' state (Drosophila melanogaster)
GLI3 is processed to GLI3R by the proteasome (Drosophila melanogaster)
CK1 phosphorylates p-GLI3 (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
Signaling by WNT (Drosophila melanogaster)
Degradation of beta-catenin by the destruction complex (Drosophila melanogaster)
AXIN is phosphorylated in the destruction complex (Drosophila melanogaster)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Drosophila melanogaster)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
Association of beta-catenin with the destruction complex (Drosophila melanogaster)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
Beta-catenin phosphorylation cascade (Drosophila melanogaster)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Drosophila melanogaster)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Drosophila melanogaster)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Drosophila melanogaster)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Drosophila melanogaster)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
Degradation of ubiquitinated beta catenin by the proteasome (Drosophila melanogaster)
p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Drosophila melanogaster)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Drosophila melanogaster)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Drosophila melanogaster)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
Phosphorylation of APC component of the destruction complex (Drosophila melanogaster)
CK1alpha (GSK3) [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P54367 CkIalpha
Gene Names
CkIalpha, CKI, CG2028
Chain
chain:1-337
Reference Genes
BioGPS Gene:32221 CkIalpha
CTD Gene:32221 CkIalpha
KEGG:dme:Dmel_CG2028 CkIalpha
Monarch:32221 CkIalpha
NCBI Gene:32221 CkIalpha
UCSC:P54367 CkIalpha
Reference Transcript
RefSeq:NM_078585.6 CkIalpha
RefSeq:NM_001169266.3 CkIalpha
RefSeq:NM_167331.4 CkIalpha
RefSeq:NM_167332.3 CkIalpha
RefSeq:NM_001298235.1 CkIalpha
RefSeq:NM_001298234.1 CkIalpha
Other Identifiers
143778_at
1623403_s_at
32221
GO:0000902
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0006281
GO:0006468
GO:0007165
GO:0016055
GO:0016740
GO:0018105
GO:0030877
GO:0030949
GO:0032436
GO:0035313
GO:0035331
GO:0042593
GO:0043226
GO:0043227
GO:0043229
GO:0045879
GO:0045880
GO:0048870
GO:0090090
GO:0106310
GO:0140096
GO:1901800
Participates
as a component of
p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
as a member of
CK1alpha (GSK3) [cytosol] (Drosophila melanogaster)
Other forms of this molecule
CKIalpha [cytosol]
CSNK1A1 [cilium]
Inferred From
CSNK1A1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_727632.1
,
NP_001285164.1
,
NP_511140.1
,
NP_001285163.1
,
NP_727631.1
,
NP_001162737.1
ENSEMBL
FBtr0300380
,
FBpp0073515
,
FBpp0311373
,
FBtr0073682
,
FBpp0311372
,
FBpp0309354
,
FBtr0345162
,
FBtr0073680
,
FBpp0073513
,
FBpp0289609
,
FBtr0345163
,
FBtr0340408
FlyBase
FBgn0015024
PRO
P54367
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P18824 arm
20
arm [nucleoplasm]
(R-DME-3451168)
arm [cytosol]
(R-DME-448839)
arm [cytosol]
(R-DME-202930)
arm [cytosol]
(R-DME-202950)
arm [plasma membrane]
(R-DME-9038440)
arm [plasma membrane]
(R-DME-437260)
phospho-arm [cytosol]
(R-DME-8942374)
phospho-arm [cytosol]
(R-DME-8942369)
phospho-arm [cytosol]
(R-DME-8942367)
phospho-arm [cytosol]
(R-DME-8942363)
phospho-arm [cytosol]
(R-DME-3134933)
phospho-arm [nucleoplasm]
(R-DME-3134926)
arm [specific granule lumen]
(R-DME-6799534)
arm [extracellular region]
(R-DME-6806309)
arm [ficolin-1-rich granule lumen]
(R-DME-6801028)
arm [cytosol]
(R-DME-201598)
Phospho (4 sites) ARM [cytosol]
(R-DME-205960)
ARM [cytosol]
(R-DME-205774)
Phospho ARM [cytosol]
(R-DME-206159)
ARM [nucleoplasm]
(R-DME-205878)
0.508
2
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